The aim of this study was to investigate the cytotoxicity effect of amyloid fibrils of hen egg-white lysozyme (HEWL) on SH-SY5Y cells. The 100 µmol.L^-1 HEWL protein was incubated with agitation at 57°C in glycine solution of pH 2.0. The ultrastructure of HEWL amyloid fibrils was observed under...

Mycotoxin is widely found in feed, the detection rate of mycotoxin in feed in China is as high as 90%, and among them the most harmful mycotoxin to animal husbandry mainly has 6 kinds. When livestock and poultry consume such feed, mycotoxin will cause chronic poisoning, disease and even death of...

With the advent of molecular technology, several isothermal techniques for rapid detection of zoonotic pathogens have been developed. Among them, recombinase polymerase amplification (RPA) is becoming an important technology for rapid, sensitive, and economical detection of zoonotic pathogens. RPA...

Trichomonas gallinae (T. gallinae) is an infectious parasite that is prevalent worldwide in poultry and can cause death in both poultry and wild birds. Although studies have shown that T. gallinae damages host cells through direct contact, the mechanism is still unclear. In this study, we found...

Objective: To learn about the infection status of Anisakis larvae in the major economic marine products in the Yellow Sea and Bohai Sea, and provide baseline data for systematic monitoring of Anisakis and prevention and control of related diseases. Methods: From April 2016 to September 2020, the...

Zearalenone (ZEN), a mycotoxin is frequently detected in different food products and has been widely studied for its toxicity. However, the underlying mechanisms of hepatotoxic effects, relationship between gut microbiome and liver metabolite mediated hepatotoxicity mechanisms induced by ZEN are...

Baylisascaris procyonis is an intestinal nematode that uses raccoons as its definitive host, but larvae can infect more than 130 types of animals, including humans (as a paratenic host). B. procyonis is a serious zoonotic parasite that can cause fatal neural larva migrans (NLM), ocular larva...

The present experiment was conducted to evaluate the effects of single and combined exposure of deoxynivalenol (DON) and aflatoxin B₁ (AFB₁) on intestinal microflora diversity and species abundance in mice. Ninety-six Kunming mice (male, 18-day-old) were randomly divided into 4 groups with 24 mice...

Chemical drugs, such as antibiotics, were still important materials to prevent and cure diseases of aquatic organisms. However, antibiotics abuse do not only make the effects little, but also cause other bad problems, such as bacterial resistance and drug residues. Therefore, seeking the effective...

Vibrio alginolyticus, a Gram-negative halophilic zoonotic pathogen, can cause bacterial hemorrhagic septicemia in various aquaculture species and wound infections in humans. V. alginolyticus brings about huge economic losses in aquaculture all around the world. Hfq, a ubiquitous RNA-binding...