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The One Health Hub is a knowledge, evidence, and learning platform that promotes a cross-sectoral One Health agenda encompassing human, animal, plant, and ecosystem health. It identifies gaps in knowledge, analyses evidence, and helps to shape policies for a more interconnected approach to health. The platform works with global and regional organizations to help mainstream a One Health approach in sustainable development. It also supports global development initiatives by helping them to embed One Health thinking in their programming. The One Health Hub is managed by CABI with funding from UK International Development from the UK government, and works in partnership with the Juno Evidence Alliance.