Zoonotic tuberculosis in humans is caused by infection with bacteria of the Mycobacterium tuberculosis complex acquired from animals, most commonly cattle. India has the highest burden of human tuberculosis in the world and any zoonotic risk posed by tuberculosis in bovines needs to be managed at...

Tuberculosis is a chronic and contagious infectious disease caused by multi-host species of the genus Mycobacterium grouped within the Mycobacterium tuberculosis complex. These pathogenic bacteria mainly affect mammals, including humans. The most recognized species is Mycobacterium bovis, the...

Antibacterial peptides are an important part of the innate immune system, and LL-37 is the only antimicrobial peptide known to be expressed in humans. LL-37 has anti-tuberculosis activity and immunomodulatory functions, and it has been found to be a diagnostic marker for tuberculosis. This research ...

Mycobacterium tuberculosis (M. tuberculosis) can replicate in the macrophage by interfering with many host protein functions. While it is far from known these host proteins for controlling M. tuberculosis infection. Herein, we infected macrophages including THP-1 and Raw264.7 cells with M. ...

A questionnaire survey was conducted on the knowledge, attitude and practices of butchers on tuberculosis in small ruminants in selected areas of Katsina State, Nigeria. All respondents had some level of formal education. Animals slaughtered included cattle (18.0%), sheep (34.0%), goats (53.0%) and ...

Tuberculosis in animals is an infectious and contagious disease, caused by acid-fast bacilli of the Mycobacterium tuberculosis complex. The disease has been confirmed in Poland in farm and wild animals. Among the latter the largest number of cases was diagnosed in free-ranging European bison in the ...

We aimed to assess the proportion of tuberculosis in humans and tuberculosis (TB)-associated abattoir condemnations from the animal sector, as well as determine risk factors of zoonotic tuberculosis at the animal-human interface in Zambia. The study involved 255 presumptive TB patients and 156...

Tuberculosis (TB) remains among the most serious infectious diseases worldwide. Existing TB diagnostic methods cannot effectively distinguish latent infection from active TB cases, thus delaying follow-up intervention and treatment. The content of biomarkers varies in different stages of latent ...

Background: Tuberculosis affects millions of people worldwide. The emergence of drug-resistant Mycobacterium tuberculosis strains has made treatment more difficult. A drug discovery project initiated to screen natural products identified a lead stilbene compound, and structure function analysis of...

Introduction: Diabetes is a potent risk factor for the activation of latent tuberculosis and worsens the tuberculosis (TB) treatment outcome. The major reason for mortality and morbidity in diabetic patients is due to their increased susceptibility to TB. Thus, the study was conducted to understand ...