Tuberculosis is a chronic and contagious infectious disease caused by multi-host species of the genus Mycobacterium grouped within the Mycobacterium tuberculosis complex. These pathogenic bacteria mainly affect mammals, including humans. The most recognized species is Mycobacterium bovis, the...
Author(s)
Ponce, L. C.; Gallardo, M. J.; Marfil, M. J.; Petta, A.; Vivot, M. M.; Barandiaran, S.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Indian Journal of Tuberculosis, 2023, 70, 1, pp 120-123
Interest in host-directed therapies as alternatives/adjuncts to antibiotic treatment has resurged with the increasing prevalence of antibiotic-resistant tuberculosis (TB). Immunotherapies that reinvigorate immune responses by targeting immune checkpoints like PD-1/PD-L1 have proved successful in...
Author(s)
Zheng Nan; Fleming, J.; Hu PeiLei; Jiao JianJian; Zhang GuoQin; Yang RuiFang; Li ChuanYou; Liu Yi; Bi LiJun; Zhang HongTai
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Microbiology Spectrum, 2022, 10, 1,
Tuberculosis, an infectious disease, is one of the leading causes of death worldwide. Drug-resistant tuberculosis exacerbates its threat. Despite long-term and costly treatment with second-line drugs, treatment failure rates and mortality remain high. Therefore, new strategies for developing new...
Author(s)
Seo, H.; Kim, S.; Mahmud, H. A.; Sultana, O. F.; Lee, Y.; Yoon, Y.; Rahim, M. A.; Jo, S.; Choi, J.; Lee, S.; Song, H. Y.
Publisher
MDPI AG, Basel, Switzerland
Citation
Antibiotics, 2022, 11, 10,
Tuberculosis (TB) is caused by the Mycobacterium tuberculosis complex (MTBC), a bacterial group of clonally evolved pathogens that infect humans and animals. Despite a high genetic similarity, MTBC members demonstrate different host tropism and virulence. While Mycobacterium tuberculosis is the...
Publisher
Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, Brazil
Citation
Adaptação de Mycobacterium tuberculosis e Mycobacterium bovis a hospedeiros: uma análise genômica e transcricional, 2022, pp 185 pp.
Pathogenic mycobacteria induce and accelerate blood vessel formation driven by extensive inflammation during granuloma formation, which is a central feature of mycobacterial pathogenesis. Tumor necrosis factor-alpha (TNF-α) enhances the expression of vascular endothelial growth factor (VEGF) and...
Author(s)
Davuluri, K. S.; Singh, A. K.; Vimal Kumar; Singh, S. V.; Singh, A. V.; Santhosh Kumar; Rajbala Yadav; Shweta Kushwaha; Chauhan, D. S.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Tuberculosis, 2022, 135,
Bovine tuberculosis is a zoonosis that has a chronic evolution, caused by the bacterium Mycobacterium bovis, whose definitive host is the bovine. However, this agent can infect other hosts, including man. Bovine tuberculosis is responsible for significant economic losses to livestock and is an...
Author(s)
Hoffmann, E. R.; Buss, B.; Pereira, M. M.; Reis, D.; Teixeira, M. C.; Moscon, L. A.; Rondon, D. A.; Pereira, C. M.
Publisher
Pubvet, Maringá, Brazil
Citation
PUBVET, 2022, 16, 6,
Tuberculosis remains a public health crisis and a health security threat. There is an urgent need to develop new antituberculosis drugs with novel modes of action to cure drug-resistant tuberculosis and shorten the chemotherapy period by sterilizing tissues infected with dormant bacteria. Lysocin E ...
Author(s)
Geberetsadik, G.; Inaizumi, A.; Nishiyama, A.; Yamaguchi, T.; Hamamoto, H.; Panthee, S.; Tamaru, A.; Hayatsu, M.; Mizutani, Y.; Kaboso, S. A.; Hakamata, M.; Ilinov, A.; Ozeki, Y.; Tateishi, Y.; Sekimizu, K.; Matsumoto, S.
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Antimicrobial Agents and Chemotherapy, 2022, 66, 9,
The Mycobacterium tuberculosis complex (MTBC) contains the causative agents of tuberculosis (TB) in mammals. The archetypal members of the MTBC, Mycobacterium tuberculosis and Mycobacterium bovis, cause human tuberculosis and bovine tuberculosis, respectively. Although M. tuberculosis and M. bovis...
Author(s)
Ma RuoYao; Farrell, D.; Gonzalez, G.; Browne, J. A.; Nakajima, C.; Suzuki, Y.; Gordon, S. V.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Microbiology, 2022, 13, April,
Linezolid (LZD) was the first oxazolidinone approved for treating drug-resistant tuberculosis. A newly approved regimen combining LZD with bedaquiline (BDQ) and pretomanid (PMD) (BPaL regimen) is the first 6-month oral regimen that is effective against multidrug- and extensively drug-resistant ...
Author(s)
Liu HaiTing; Zhu Hui; Fu Lei; Zhang WeiYan; Chen Xi; Wang Bin; Guo ShaoChen; Ding YangMing; Wang Ning; Li DongShuo; Lu Yu
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Antimicrobial Agents and Chemotherapy, 2023, 67, 2,
Brucellosis and tuberculosis are important zoonotic diseases with high economic and public health importance mainly in low income countries. In Burkina Faso, studies have been implemented to assess prevalence of these diseases but data remain scare about the prevalence in extensive husbandry...
Author(s)
Dahourou, L. D.; Ouoba, L. B.; Minoungou, L. B. G.; Tapsoba, A. R. S.; Savadogo, M.; Yougbaré, B.; Traoré, A.; Alambédji, R. B.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Scientific African, 2023, 19,