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Abstract

Characterizing transcription start sites is essential for understanding the regulatory mechanisms that control gene expression. Recently, a new bovine genome assembly (ARS-UCD1.2) with high continuity, accuracy, and completeness was released; however, the functional annotation of the bovine genome...

Author(s)
Goszczynski, D. E.; Halstead, M. M.; Islas-Trejo, A. D.; Zhou HuaiJun; Ross, P. J.
Publisher
Cold Spring Harbor Laboratory Press, New York, USA
Citation
Genome Research, 2021, 31, 4, pp 732-744
Abstract

ZNFO is a Krüppel-associated box (KRAB) containing zinc finger transcription factor, which is exclusively expressed in bovine oocytes. Previous studies have demonstrated that ZNFO possesses an intrinsic transcriptional repressive activity and is essential for early embryonic development in cattle....

Author(s)
Zhang MingXiang; Chaney, H. L.; Current, J. Z.; Yao JianBo
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2021, 791,
Abstract

Analysing the molecular regulation mechanism of fat deposition in yellow cattle can provide a theoretical basis for the breeding of excellent beef cattle. ANGPTL8 (angiopoietin-like protein 8) promotes the formation of lipid droplets during adipocyte differentiation. To explore the promoter active...

Author(s)
Wei XueFeng; Zhu YunChang; Du Jie; Ma XiaoJie; Zhao Xue; Ma YaoYao; Han Shuang; Ma Yun
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2021, 784,
Abstract

Alpha/beta hydrolase domain 5 (ABHD5) plays a significant role in intracellular lipid metabolism, which is regulated by a complex network of transcription factors. The transcriptional regulation of the ABHD5 gene in cattle and other livestock, however, has not been previously investigated....

Author(s)
Wang XiaoYu; Li AnNing; Raza, S. H. A.; Liang ChengCheng; Zhang Song; Mei ChuGang; Yang WuCai; Zan LinSen
Publisher
Mary Ann Liebert, Inc., New Rochelle, USA
Citation
DNA and Cell Biology, 2021, 40, 2, pp 219-230
Abstract

Anti-angiogenic therapy is a cancer treatment strategy targeting new blood vessel formation. Microvessel density (MVD) is a histopathological method for evaluating angiogenesis and endoglin is used as an activated endothelial marker in human medicine. The assessment of the treatment effect using...

Author(s)
Kimura, M.; Yamasaki, M.; Satoh, H.; Uchida, N.
Publisher
Wiley, Oxford, UK
Citation
Veterinary and Comparative Oncology, 2020, 19, 1, pp 34-43
Abstract

OBJECTIVE: To characterize transcription of profibrotic mediators in renal tissues of cats with ischemia-induced chronic kidney disease (CKD). SAMPLE Banked renal tissues from 6 cats with experimentally induced CKD (RI group) and 8 healthy control cats. PROCEDURES: For cats of the RI group, both...

Author(s)
Lourenço, B. N.; Coleman, A. E.; Schmiedt, C. W.; Brown, C. A.; Rissi, D. R.; Stanton, J. B.; Giguère, S.; Berghaus, R. D.; Brown, S. A.; Tarigo, J. L.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2020, 81, 2, pp 180-189
Abstract

Previous studies suggest a negative relationship between hepatic oxidative stress and productivity in beef cattle. Uncoupling protein 2 (UCP2) is involved in the disappearance of reactive oxygen species, suggesting the defensive role of UCP2 against oxidative stress. The present study examined the...

Author(s)
Kim, D. H.; Sadakane, H.; Nishikiori, Y.; Matsumura, M.; Ikeda, M.; Diao, Z.; Jha, R.; Murakami, M.; Matsui, T.; Funaba, M.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2020, 82, 12, pp 1734-1741
Abstract

This study was conducted to investigate the molecular mechanism of bta-miR-677 regulating the expression of type I interferon (IFN). Bta-miR-677 was transfected into MDBK cells to detect the transcription level of type I IFN and interferon stimulating genes (ISGs). Then we predicted the target gene ...

Author(s)
Liao Zheng; Ji XinQin; Li JiZong; Xiao Fang; Liu MaoJun; Mao Li; Li WenLiang; Sun Min
Publisher
Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China
Citation
Acta Veterinaria et Zootechnica Sinica, 2020, 51, 1, pp 150-158
Abstract

Proper oocyte maturation is a prerequisite for successful reproduction and requires the resumption of meiosis to the metaphase II stage (MII). In bovine oocytes, nuclear maturation has been shown to occur in in vitro maturing cumulus-enclosed oocytes (COCs) in the absence of transcription, but...

Author(s)
Gegenfurtner, K.; Flenkenthaler, F.; Fröhlich, T.; Wolf, E.; Arnold, G. J.
Publisher
Oxford University Press, Cary, USA
Citation
Biology of Reproduction, 2020, 103, 5, pp 1000-1011
Abstract

The purpose of this study was to assess the effects of acetate and β-hydroxybutyrate alone or in combination on lipogenic genes and their associated regulatory proteins in dairy cow mammary epithelial cells (DCMEC) using quantitative reverse transcription polymerase chain reaction (qRT-PCR),...

Author(s)
Ali Ilyas; Li ChengMin; Li Lian; Kuang MeiQian; Shafiq Muhammad; Wang YiRu; Yang Min; Wang GenLin
Publisher
Springer, Dordrecht, Netherlands
Citation
In Vitro Cellular & Developmental Biology - Animal, 2021, 57, 1, pp 66-75

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