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Abstract

OBJECTIVE: To characterize delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) features of healthy hyaline cartilage of the distal interphalangeal joint (DIPJ) of horses, to determine whether dGEMRIC can be used to differentiate various stages of naturally occurring osteoarthritis of the DIPJ,...

Author(s)
Bischofberger, A. S.; Fürst, A. E.; Torgerson, P. R.; Carstens, A.; Hilbe, M.; Kircher, P.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2018, 79, 3, pp 287-298
Abstract

We report the results of a symposium aimed at identifying validated biomarkers that can be used to complement clinical observations for diagnosis and prognosis of joint injury leading to equine osteoarthritis (OA). Biomarkers might also predict pre-fracture change that could lead to catastrophic...

Author(s)
McIlwraith, C. W.; Kawcak, C. E.; Frisbie, D. D.; Little, C. B.; Clegg, P. D.; Peffers, M. J.; Karsdal, M. A.; Ekman, S.; Laverty, S.; Slayden, R. A.; Sandell, L. J.; Lohmander, L. S.; Kraus, V. B.
Publisher
Wiley, Hoboken, USA
Citation
Journal of Orthopaedic Research, 2018, 36, 3, pp 823-831
Abstract

This study was aimed to describe the extremity temperature alterations of horses with bucked shin complex, splints, carpal osteoarthritis and sesamoiditis. In this study, 27 race horses with different breed (24 Arabian, three Thoroughbred), sex (23 males, four mares) and age (avg. 3.5-year-old)...

Author(s)
Yanmaz, L. E.; Okumuș, Z.
Publisher
Erciyes University, Faculty of Veterinary Medicine, Kayseri, Turkey
Citation
Erciyes Üniversitesi Veteriner Fakültesi Dergisi, 2018, 15, 1, pp 41-45
Abstract

Background: There is limited information available concerning normal equine meniscal morphology, its degeneration and role in osteoarthritis (OA). Objectives: To characterise normal equine meniscal morphology and lesions and to explore the relationship between equine meniscal degeneration and...

Author(s)
Dubuc, J.; Girard, C.; Richard, H.; Lasalle, J. de; Laverty, S.
Publisher
Wiley, Oxford, UK
Citation
Equine Veterinary Journal, 2018, 50, 1, pp 133-140
Abstract

We hypothesised that shorter treatment intervals of intraarticular autologous conditioned serum (ACS) injections would more beneficially affect the synovial fluid (SF) concentrations of IL-1ra, IL-1β and cartilage biomarkers, compared with the traditional weekly treatment intervals in joints...

Author(s)
Lasarzik, J.; Bondzio, A.; Rettig, M.; Estrada, R.; Klaus, C.; Ehrle, A.; Einspanier, R.; Lischer, C. J.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2018, 60, pp 35-42
Abstract

Objective: The purpose of this study was to determine whether there was a correlation between circulating and intra-synovial Dkk-1 and radiographic signs of equine osteoarthritis. Methods: Circulating and intra-synovial Dkk-1 levels were measured in clinical cases using a commercially available...

Author(s)
Mills, J. S.; Kinsley, M. A.; Peters, D. F.; Weber, P. S. D.; Shearer, T. R.; Pease, A. P.
Publisher
Schattauer GmbH, Stuttgart, Germany
Citation
Veterinary and Comparative Orthopaedics and Traumatology, 2017, 30, 5, pp 311-317
Abstract

A great deal of research is done for decades to elucidate the complexity of osteoarthritis pathology and to develop therapeutic strategies with symptom and diseases modifying ability. In the recent years, basic knowledge of the synthesis and mechanism of 1L-1β and IL-1ra was determined, which are...

Author(s)
Lasarzik, J.
Publisher
Freien Universität Berlin, Berlin, Germany
Citation
Interleukin-1 receptor antagonist and interleukin-1 beta levels in equine synovial fluid of normal and osteoarthritic joints and the influence of two different autolougous conditioned serum treatment intervals on cytokine and cartilage biomarker levels in equine osteoarthritic joints, 2017, pp 41 pp.
AbstractFull Text

Author(s)
Cruz, A. M.
Publisher
North American Veterinary Community (NAVC), Orlando, USA
Citation
NAVC Conference Proceedings, Orlando, Florida, USA, 4-8 February 2017. Large Animal, 2017, pp 90-96
Abstract

Introduction: The study aimed to clarify the changes in the concentration of inflammatory mediators, proteases, and cartilage degradation biomarkers in the synovial fluid of joints in an equine osteoarthritis model. Material and Methods: Osteoarthritis was induced in eight Mongolian horses by a...

Author(s)
Ma TianWen; Li Yue; Wang GuanYing; Li XinRan; Jiang RenLi; Song XiaoPeng; Zhang ZhiHeng; Bai Hui; Li Xin; Gao Li
Publisher
De Gruyter Open, Warsaw, Poland
Citation
Journal of Veterinary Research, 2017, 61, 4, pp 503-508
Abstract

Background: Clinical tools to diagnose the early changes of osteoarthritis (OA) that occur in the articular cartilage are lacking. Objectives: We sought to identify and quantify a novel cartilage oligomeric matrix protein (COMP) neoepitope in the synovial fluid from the joints of healthy horses and ...

Author(s)
Skiöldebrand, E.; Ekman, S.; Hultén, L. M.; Svala, E.; Björkman, K.; Lindahl, A.; Lundqvist, A.; Önnerfjord, P.; Sihlbom, C.; Rüetschi, U.
Publisher
Wiley, Oxford, UK
Citation
Equine Veterinary Journal, 2017, 49, 5, pp 662-667

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