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Abstract

Osteoarthritis commonly causes lameness in the horse and has a great impact in performance animals. Due to the limitations of current medical therapies, allogenic mesenchymal stem cells (MSCs) may become an alternative method to control inflammation, reduce tissue damage and pain, and therefore...

Author(s)
Mariñas-Pardo, L.; García-Castro, J.; Rodríguez-Hurtado, I.; Rodríguez-García, M. I.; Núñez-Naveira, L.; Hermida-Prieto, M.
Publisher
Mary Ann Liebert, Inc., New Rochelle, USA
Citation
Stem Cells and Development, 2018, 27, 17, pp 1147-1160
Abstract

Due to limited possibilities to diagnose degenerative joint diseases (DJD) such as osteoarthritis at early stages, potential biomarkers are frequently investigated. The relationship of activity of matrix metalloproteinase (proMMP)-9 to clinical, arthroscopic and synovial fluid (SF) parameters, and...

Author(s)
Lerchbacher, J.; Häussler, V.; Bräuning, C.; Richter, I. G.; Barnewitz, D.
Publisher
Hippiatrika Verlag GmbH, Baden-Baden, Germany
Citation
Pferdeheilkunde, 2018, 34, 6, pp 563-573
Abstract

OBJECTIVE: To characterize delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) features of healthy hyaline cartilage of the distal interphalangeal joint (DIPJ) of horses, to determine whether dGEMRIC can be used to differentiate various stages of naturally occurring osteoarthritis of the DIPJ,...

Author(s)
Bischofberger, A. S.; Fürst, A. E.; Torgerson, P. R.; Carstens, A.; Hilbe, M.; Kircher, P.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2018, 79, 3, pp 287-298
Abstract

We report the results of a symposium aimed at identifying validated biomarkers that can be used to complement clinical observations for diagnosis and prognosis of joint injury leading to equine osteoarthritis (OA). Biomarkers might also predict pre-fracture change that could lead to catastrophic...

Author(s)
McIlwraith, C. W.; Kawcak, C. E.; Frisbie, D. D.; Little, C. B.; Clegg, P. D.; Peffers, M. J.; Karsdal, M. A.; Ekman, S.; Laverty, S.; Slayden, R. A.; Sandell, L. J.; Lohmander, L. S.; Kraus, V. B.
Publisher
Wiley, Hoboken, USA
Citation
Journal of Orthopaedic Research, 2018, 36, 3, pp 823-831
Abstract

This study was aimed to describe the extremity temperature alterations of horses with bucked shin complex, splints, carpal osteoarthritis and sesamoiditis. In this study, 27 race horses with different breed (24 Arabian, three Thoroughbred), sex (23 males, four mares) and age (avg. 3.5-year-old)...

Author(s)
Yanmaz, L. E.; Okumuș, Z.
Publisher
Erciyes University, Faculty of Veterinary Medicine, Kayseri, Turkey
Citation
Erciyes Üniversitesi Veteriner Fakültesi Dergisi, 2018, 15, 1, pp 41-45
Abstract

Background: There is limited information available concerning normal equine meniscal morphology, its degeneration and role in osteoarthritis (OA). Objectives: To characterise normal equine meniscal morphology and lesions and to explore the relationship between equine meniscal degeneration and...

Author(s)
Dubuc, J.; Girard, C.; Richard, H.; Lasalle, J. de; Laverty, S.
Publisher
Wiley, Oxford, UK
Citation
Equine Veterinary Journal, 2018, 50, 1, pp 133-140
Abstract

We hypothesised that shorter treatment intervals of intraarticular autologous conditioned serum (ACS) injections would more beneficially affect the synovial fluid (SF) concentrations of IL-1ra, IL-1β and cartilage biomarkers, compared with the traditional weekly treatment intervals in joints...

Author(s)
Lasarzik, J.; Bondzio, A.; Rettig, M.; Estrada, R.; Klaus, C.; Ehrle, A.; Einspanier, R.; Lischer, C. J.
Publisher
Elsevier, New York, USA
Citation
Journal of Equine Veterinary Science, 2018, 60, pp 35-42
Abstract

Subchondral bone plays a critical role in the pathogenesis of osteochondral disease across veterinary species. The subchondral bone is highly adaptable, with the ability to model and remodel in response to loading stresses experienced by the joint. Repetitive stress injuries within the joint can...

Author(s)
Stewart, H. L.; Kawcak, C. E.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, August, pp 178
Abstract

Background: This study aimed at assessing the effectiveness and safety of repeated administrations of allogeneic bone marrow-derived mesenchymal stem cells (BM-MSCs) primed with tumor necrosis factor (TNF)-α and interferon-γ in an equine model of chemically-induced osteoarthritis. Arthritis was...

Author(s)
Barrachina, L.; Remacha, A. R.; Romero, A.; Vitoria, A.; Albareda, J.; Prades, M.; Roca, M.; Zaragoza, P.; Vázquez, F. J.; Rodellar, C.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2018, 14, 241, pp (17 August 2018)
AbstractFull Text

Author(s)
Cruz, A. M.
Publisher
North American Veterinary Community (NAVC), Orlando, USA
Citation
NAVC Conference Proceedings, Orlando, Florida, USA, 4-8 February 2017. Large Animal, 2017, pp 90-96

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