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Abstract

Background: Cumulating evidence from rodent models points to a pathophysiological role of inflammatory signaling in the epileptic brain with Toll-like receptor-4 signaling acting as one key factor. However, there is an apparent lack of information about expression alterations affecting this pathway ...

Author(s)
Rüden, E. L. von; Gualtieri, F.; Schönhoff, K.; Reiber, M.; Wolf, F.; Baumgärtner, W.; Hansmann, F.; Tipold, A.; Potschka, H.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2020, 16, 18, pp (20 January 2020)
Abstract

Background: High epilepsy prevalence and incidence have been reported in areas with high onchocerciasis transmission. Recent findings suggest that proper community-directed treatment with ivermectin (CDTI) is potentially able to prevent onchocerciasis-associated epilepsy (OAE). We assessed the ...

Author(s)
Siewe, J. N. F.; Ukaga, C. N.; Nwazor, E. O.; Nwoke, M. O.; Nwokeji, M. C.; Onuoha, B. C.; Nwanjor, S. O.; Okeke, J.; Osahor, K.; Chimechefulam, L.; Ogomaka, A. I.; Amaechi, A. A.; Ezenwa, C. I.; Ezike, M. N.; Ikpeama, C.; Nwachukwu, O.; Eriama-Joseph, A. I.; Nwoke, B. E. B.; Colebunders, R.
Publisher
BioMed Central Ltd, London, UK
Citation
Infectious Diseases of Poverty, 2019, 8, 8, pp (23 January 2019)
Abstract

Background: Onchocerciasis-endemic regions are known to have a high epilepsy prevalence. Limited resources in these areas and poor access to healthcare by persons with epilepsy (PWE) result in a wide anti-epileptic treatment gap, poor seizure control and a high burden of seizure-related...

Author(s)
Fodjo, J. N. S.; Dekker, M. C. J.; Idro, R.; Mandro, M. N.; Preux, P. M.; Njamnshi, A. K.; Colebunders, R.
Publisher
BioMed Central Ltd, London, UK
Citation
Infectious Diseases of Poverty, 2019, 8, 11, pp (10 February 2019)
Abstract

Background: In onchocerciasis-endemic areas, particularly in those with a sub-optimal onchocerciasis control programme, a high prevalence of epilepsy is observed. Both onchocerciasis and epilepsy are stigmatizing conditions. The first international workshop on onchocerciasis-associated epilepsy...

Author(s)
O'Neill, S.; Irani, J.; Fodjo, J. N. S.; Nono, D.; Abbo, C.; Sato, Y.; Mugarura, A.; Dolo, H.; Ronse, M.; Njamnshi, A. K.; Colebunders, R.
Publisher
BioMed Central Ltd, London, UK
Citation
Infectious Diseases of Poverty, 2019, 8, 34, pp (20 May 2019)
Abstract

Background: A high prevalence of epilepsy has been observed in many onchocerciasis endemic regions. This study is to estimate the prevalence of active epilepsy and exposure to Onchocerca volvulus infection in a rural population in Ituri province, Democratic Republic of Congo. Methods: In August...

Author(s)
Lenaerts, E.; Mandro, M.; Mukendi, D.; Suykerbuyk, P.; Dolo, H.; Wonya'Rossi, D.; Ngave, F.; Ensoy-Musoro, C.; Laudisoit, A.; Hotterbeekx, A.; Colebunders, R.
Publisher
BioMed Central Ltd, London, UK
Citation
Infectious Diseases of Poverty, 2018, 7, 68, pp (1 August 2018)
Abstract

Temporal lobe epilepsy is a chronic disorder of nerve system, mainly characterized by hippocampal sclerosis with massive neuronal loss and severe gliosis. Aberrant neurogenesis has been shown in the epileptogenesis process of temporal lobe epilepsy. However, the molecular mechanisms underlying...

Author(s)
Qu ZhengYi; Su Fang; Qi XueTing; Sun JianBo; Wang HongCai; Qiao ZhenKui; Zhao Hong; Zhu YuLan
Publisher
Wiley, Copenhagen, Denmark
Citation
Cell Biochemistry and Function, 2017, 35, 7, pp 472-476
Abstract

To evaluate the localization of functional deficit area in epileptogenic zones of the brain in seven refractory and seven non-refractory epilepsy dogs using technetium 99 m labeled with ethyl cysteinate dimer and interictal single photon emission computed tomography [99 mTc-ECD SPECT]...

Author(s)
Huaijantug, S.; Theeraphun, W.; Suwanna, N.; Thongpraparn, T.; Chanachai, R.; Aumarm, W.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2020, 82, 5, pp 553-558
Abstract

Epilepsy is one of the most common diseases of the nervous system. Neuronal apoptosis is closely involved in the development and progression of epilepsy. Triptolide is a widely used immunosuppressive agent in traditional Chinese medicine. However, a neuroprotective role of triptolide in epilepsy...

Author(s)
Jiang JingZi; Feng JunLin; Wu Lan; Liang Jing; He YuChan; Li ChaoQian
Publisher
New Century Health Publishers, LLC, New Orleans, USA
Citation
Current Topics in Nutraceutical Research, 2020, 18, 3, pp 284-291
Abstract

Epilepsy is a common, complex and often challenging neurological disorder to treat in the dog, with 20-30% of dogs resistant to conventional medical therapies, and associated with cognitive and behavioral comorbidities and early death. Behavioral interventions are an emerging area of focus in the...

Author(s)
Packer, R. M. A.; Hobbs, S. L.; Blackwell, E. J.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2019, 6, January, pp 3
Abstract

Epilepsy is one of the most common neurologic disorders in dogs. The breed related prevalence can reach up to 5-6% in the canine population. In the past decade the veterinary availability of several new diagnostic methods has dramatically improved and this has opened new horizons in the diagnostic...

Author(s)
Lőrincz, B. A.; Csébi, P.; Bajzik, G.; Garamvölgyi, R.
Publisher
NAKVI, Budapest, Hungary
Citation
Magyar Állatorvosok Lapja, 2017, 139, 9, pp 553-566

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