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Cardiac biomarkers and key clinical findings have been identified that can help veterinary practitioners identify dogs with degenerative mitral valve disease that are at highest risk of death.

Date
6 November 2018
Abstract

Alacepril is a relatively novel angiotensin-converting enzyme inhibitor; however, the safety, tolerance, and efficacy of alacepril in terms of cough suppression in dogs with mitral valve disease (MVD) remain unknown. The aim of this study was to investigate the safety, tolerance, and cough...

Author(s)
Hori, Y.; Nakamura, K.; Kanno, N.; Hitomi, M.; Yamashita, Y.; Hosaka, S.; Isayama, N.; Mimura, T.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2018, 80, 8, pp 1212-1218
Abstract

Objectives: To investigate QT instability in dogs with myxomatous mitral valve disease (MMVD) and to determine if this is associated with arrhythmogenesis. Animals: One hundred sixty-seven MMVD dogs that met the study criteria were included. Methods: Echocardiographic and electrocardiographic data...

Author(s)
Brüler, B. C.; Jojima, F. S.; Dittrich, G.; Giannico, A. T.; Sousa, M. G.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Veterinary Cardiology, 2018, 20, 4, pp 254-266
Abstract

Introduction: Serotonin (5-hydroxytryptamine [5-HT]) has several biological functions. In different species, excessive 5-HT has been linked to valvular lesions, similar to those seen in dogs with myxomatous mitral valve disease. Previous studies suggest higher 5-HT in healthy Cavalier King Charles...

Author(s)
Höglund, K.; Häggström, J.; Hanǻs, S.; Merveille, A. C.; Gouni, V.; Wiberg, M.; Willesen, J. L.; K. Mc Entee; Sørensen, L. M.; Tiret, L.; Seppälä, E. H.; Lohi, H.; Chetboul, V.; Fredholm, M.; Lequarré, A. S.; Ljungvall, I.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Veterinary Cardiology, 2018, 20, 4, pp 244-253
Abstract

Currently, separate measures are used to estimate the impact of animal diseases on mortality and animal welfare. This article introduces a novel metric, the Welfare-Adjusted Life Year (WALY), to estimate disease impact by combining welfare compromise and premature death components. Adapting the...

Author(s)
Teng TzuYun [Teng, T. Y. K. ]; Devleesschauwer, B.; Noordhout, C. M. de; Bennett, P.; McGreevy, P. D.; Chiu PoYu; Toribio, J. A. L. M. L.; Dhand, N. K.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2018, 13, 9, pp e0202580
AbstractFull Text

Six dogs were diagnosed with pulmonary hypertension (PH) secondary to chronic degenerative mitral valve disease (CDMVD) on echocardiography. Imatinib (3 mg/kg, every 24 hours, PO) was initiated without any changes to the background therapy to treat the PH. Follow-up evaluations at 1, 3, 5 and 6...

Author(s)
Leong ZiPing; Arita, S.; Hikasa, Y.
Publisher
Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand
Citation
Thai Journal of Veterinary Medicine, 2018, 48, 3, pp 499-505
AbstractFull Text

The clinical benefits of Coenzyme Q10 (CoQ10) have been well documented in heart failure patients. In veterinary medicine, however, the clinical benefits of CoQ10 have not been well established in dogs with heart diseases. This study aimed to determine the effects of CoQ10 supplementation on (1)...

Author(s)
Tachampa, K.; Lertwanakarn, T.; Atchariyasakchai, P.; Pumpitakkul, V.; Kireewan, S.; Buranakarl, C.
Publisher
Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand
Citation
Thai Journal of Veterinary Medicine, 2018, 48, 3, pp 443-452
AbstractFull Text

Myxomatous mitral valve disease (MMVD), an important disease in senile small breed dogs, leads to deterioration of cardiovascular function and impairment of functional capacity resulting in poor quality of life. Submaximal treadmill running has been used as both cardiovascular training and testing...

Author(s)
Sutayatram, S.; Buranakarl, C.; Kijtawornrat, A.; Soontornvipart, K.; Boonpala, P.; Pirintr, P.
Publisher
Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand
Citation
Thai Journal of Veterinary Medicine, 2018, 48, 3, pp 433-441
AbstractFull Text

Degenerative mitral valve disease (DMVD) is the most common acquired cardiac disease in geriatric dogs leading to impaired cardiac autonomic activity and functions. This study aimed to evaluate the heart rate (HR), blood pressure (BP), myocardial oxygen consumption (MVO2) and heart rate variability ...

Author(s)
Pirintr, P.; Saengklub, N.; Limprasutr, V.; Kijtawornrat, A.
Publisher
Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand
Citation
Thai Journal of Veterinary Medicine, 2018, 48, 3, pp 423-431
AbstractFull Text

The most common cause of heart failure in the canine population is myxomatous mitral valve disease, sometimes complicated by chronic kidney disease. Many studies have been done on the use of symmetric dimethylarginine as biomarker of renal impairment in dogs affected by chronic kidney disease, few...

Author(s)
Savarese, A.; Probo, M.; Locatelli, C.; Zanzani, S. A.; Gazzonis, A. L.; Papa, M.; Brambilla, P. G.
Publisher
Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya
Citation
Open Veterinary Journal, 2018, 8, 3, pp 318-324

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