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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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Abstract

Objectives: To evaluate the efficacy and safety of topiramate as an add-on therapy in dogs with refractory idiopathic epilepsy. Method: Prospective, open label, non-comparative clinical trial of topiramate in dogs with idiopathic epilepsy and poor seizure control despite therapeutic serum...

Author(s)
Kiviranta, A. M.; Laitinen-Vapaavuori, O.; Hielm-Björkman, A.; Jokinen, T.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Small Animal Practice, 2013, 54, 10, pp 512-520
Abstract

To date there is no evidence-based data for efficacious treatment of neuropathic pain in dogs with Chiari-like malformation (CM) and syringomyelia (SM). The objective of this prospective cross-over study was to compare the effect of gabapentin versus topiramate, as an add-on treatment to carprofen, ...

Author(s)
Plessas, I. N.; Volk, H. A.; Rusbridge, C.; Vanhaesebrouck, A. E.; Jeffery, N. D.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record, 2015, 177, 11, pp 288
AbstractFull Text

This paper presents practical tips to approach seizures in dogs focusing on antiepileptic therapy. Also, a brief discussion of the use of phenobarbital, potassium bromide, zonisamide, levetiracetam, topiramate was presented.

Author(s)
Duque, C.
Publisher
Ontario Veterinary Medical Association (OVMA), Milton, Canada
Citation
2019 OVMA (Ontario Veterinary Medical Association) Conference, Toronto, Canada, 31 January-2 February 2019, 2019, pp 88-92
Abstract

Rationale: Barriers to developing treatments for human status epilepticus include the inadequacy of experimental animal models. In contrast, naturally occurring canine epilepsy is similar to the human condition and can serve as a platform to translate research from rodents to humans. The objectives ...

Author(s)
Vuu, I.; Coles, L. D.; Maglalang, P.; Leppik, I. E.; Worrell, G.; Crepeau, D.; Usha Mishra; Cloyd, J. C.; Patterson, E. E.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2016, 3, December, pp 107
CABI Book Chapter Info
Cover for Topiramate.

The mechanism of action, metabolism, administration methods, adverse reactions, and pharmacokinetics of topiramate as an anticonvulsant agent in treating epilepsy in dogs and cats are discussed.

Author(s)
Platt, S.
ISBN
2014 CABI (H ISBN 9781780641096)
Type
Book chapter
AbstractFull Text

Author(s)
DeBoer, D. J.
Publisher
Ontario Veterinary Medical Association (OVMA), Milton, Canada
Citation
2019 OVMA (Ontario Veterinary Medical Association) Conference, Toronto, Canada, 31 January-2 February 2019, 2019, pp 58-59
Abstract

Over the last decade, experience was gained with the use of newer human anticonvulsive medications for treating epilepsy in dogs. In addition, a new drug (imepitoin) was introduced on the European veterinary market. This paper provides an overview of the characteristics, advantages and...

Author(s)
Flegel, T.
Publisher
Federation of European Companion Animal Veterinary Associations (FECAVA), Paris, France
Citation
European Journal of Companion Animal Practice, 2014, 24, 1, pp 48-55
Abstract

Author(s)
Charalambous, M.; Brodbelt, D.; Volk, H.
Publisher
RCVS Knowledge, London, UK
Citation
Veterinary Evidence, 2016, 1, 1, pp 9
CABI Book Info
Cover for Canine and feline epilepsy: diagnosis and management.

The authors of this 591-paged book collaborated in order to provide information on multiple aspects of canine and feline seizures and epilepsy such as pathophysiology, classification, aetiologies and differential diagnoses, epidemiology, diagnostic investigations and emergency and maintenance...

Author(s)
Risio, L. de; Platt, S.
ISBN
2014 CABI (H ISBN 9781780641096)
Type
Book
Abstract

Author(s)
Trevail, R.
Publisher
Veterinary Business Development Ltd, Peterborough, UK
Citation
Veterinary Times, 2015, 45, 17, pp 10, 12

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