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Abstract

Canine osteoarthritis is a common disorder seen in veterinary clinical practice and causes considerable morbidity in dogs as they age. Synovial fluid analysis is an important tool for diagnosis and treatment of canine joint disease and obtaining a total nucleated cell count (TNCC) is particularly...

Author(s)
Dusick, A.; Young, K. M.; Muir, P.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2014, 202, 3, pp 550-554
Abstract

Background: Although normal synovial fluid has been well characterized in domestic animals such as dogs, cats, horses, and cows, the available information on larger rodents is scarce. Objectives: The purpose of the study was to analyze the physical, chemical, and cytologic characteristics of the ...

Author(s)
Brombini, G. C.; Rahal, S. C.; Bergamini, B. C. S.; Lopes, R. S.; Santos, I. F. C.; Schimming, B. C.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2017, 46, 1, pp 179-182
Abstract

Background: Rapid and precise measurement of total and differential nucleated cell counts is a crucial diagnostic component of cavitary and synovial fluid analyses. Objectives: The objectives of this study included (1) evaluation of reliability and precision of canine and equine fluid total...

Author(s)
Brudvig, J. M.; Swenson, C. L.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Veterinary Clinical Pathology, 2015, 44, 4, pp 570-579
Abstract

Objective: To determine polarization of synovial macrophages during development of cruciate ligament rupture (CR) and determine whether differences in synovial macrophage polarization in CR, osteoarthritis (OA), and healthy joints exist. Study design: Prospective case-controlled study. Animals:...

Author(s)
Yarnall, B. W.; Chamberlain, C. S.; Hao ZhengLing; Muir, P.
Publisher
Wiley, Boston, USA
Citation
Veterinary Surgery, 2019, 48, 6, pp 1005-1012
Abstract

Objective: To report synovial fluid lactate concentrations in normal and pathological canine joints. Study design: Controlled, prospective study. Methods: Lactate was measured in synovial fluid using a hand-held meter and the rest of the fluid was sent to a commercial laboratory for analysis....

Author(s)
Proot, J. L. J.; Vicente, F. de; Sheahan, D. E.
Publisher
Schattauer GmbH, Stuttgart, Germany
Citation
Veterinary and Comparative Orthopaedics and Traumatology, 2015, 28, 5, pp 301-305
Abstract

OBJECTIVE: To evaluate the clinical features and pathological joint changes in dogs with erosive immune-mediated polyarthritis (IMPA). DESIGN: Retrospective case series. ANIMALS 13 dogs with erosive IMPA and 66 dogs with nonerosive IMPA. PROCEDURES: The medical record database of a veterinary...

Author(s)
Shaughnessy, M. L.; Sample, S. J.; Abicht, C.; Heaton, C.; Muir, P.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
Journal of the American Veterinary Medical Association, 2016, 249, 10, pp 1156-1164
Abstract

Background: Despite the importance of inflammation during the pathogenesis of cranial cruciate ligament disease (CCLD) in dogs and despite the latest knowledge suggesting a significant role of adipose tissue in osteoarthritis, the infrapatellar fat pad (IFP) was up to now mostly disregarded in...

Author(s)
Schmidli, M. R.; Fuhrer, B.; Kurt, N.; Senn, D.; Drögemüller, M.; Rytz, U.; Spreng, D. E.; Forterre, S.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2018, 14, 161, pp (16 May 2018)
Abstract

Cruciate ligament rupture (CR) and associated osteoarthritis (OA) is a common condition in dogs. Dogs frequently develop a second contralateral CR. This study tested the hypothesis that the degree of stifle synovitis and cranial cruciate ligament (CrCL) matrix damage in dogs with CR is correlated...

Author(s)
Sample, S. J.; Racette, M. A.; Hans, E. C.; Volstad, N. J.; Holzman, G.; Bleedorn, J. A.; Schaefer, S. L.; Waller, K. R., III; Hao ZhengLing; Block, W. F.; Muir, P.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2017, 12, 6, pp e0178086
Abstract

Objectives: The aim of this study was to evaluate the safety and collect pilot data measuring clinical effects of intravenously administered, adipose-derived, culture-expanded, allogeneic mesenchymal stem cells in dogs with elbow osteoarthritis. Materials and Methods: Dogs (n=13) with naturally...

Author(s)
Olsen, A.; Johnson, V.; Webb, T.; Santangelo, K. S.; Dow, S.; Duerr, F. M.
Publisher
Georg Thieme Verlag KG, Stuttgart, Germany
Citation
Veterinary and Comparative Orthopaedics and Traumatology, 2019, 32, 3, pp 173-181
Abstract

This cross-sectional clinical study compared inflammation, including expression of the chemokine interleukin (IL)-8 and intercellular cell adhesion molecule-1 (ICAM-1), in the stifle joints of 4 control dogs and 23 dogs with cranial cruciate ligament rupture (CCLR). The CCL, synovial membrane,...

Author(s)
El-Hadi, M.; Chandarshekhar Charavaryamath; Aebischer, A.; Smith, C. W.; Shmon, C.; Baljit Singh
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Journal of Veterinary Research, 2012, 76, 1, pp 8-15

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