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Abstract

Background: Occult (or atypical) hyperadrenocorticism (HAC) shows clinical signs and laboratory abnormalities similar to classic hyperadrenocorticism, but normal signs in routine screening tests such as the corticotropin (ACTH) stimulation test and low-dose dexamethasone suppression test (LDDST)....

Author(s)
Park SuMin; Kim KyeongBo; Song WooJin; Youn HwaYoung
Publisher
Wiley, Oxford, UK
Citation
Veterinary Medicine and Science, 2021, 7, 4, pp 1150-1153
Abstract

Background: Lowering the cosyntropin dose needed for ACTH stimulation would make the test more economical. Objectives: To compare the cortisol response to 1 and 5 µg/kg cosyntropin IV in dogs being screened for hyperadrenocorticism (HAC) and in dogs receiving trilostane or mitotane for...

Author(s)
Aldridge, C.; Behrend, E. N.; Kemppainen, R. J.; Lee-Fowler, T. M.; Martin, L. G.; Ward, C. R.; Bruyette, D.; Pannu, J.; Gaillard, P.; Lee, H. P.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2016, 30, 5, pp 1637-1641
Abstract

Background: Maximal aldosterone secretion in healthy dogs occurs 30 minutes postadrenocorticotropin (ACTH; 5 µg/kg IV) stimulation. The effect of trilostane and mitotane on aldosterone at that time is unknown. Objectives: To assess the effect of trilostane and mitotane in dogs with...

Author(s)
Reid, L. E.; Behrend, E. N.; Martin, L. G.; Kemppainen, R. J.; Ward, C. R.; Lurye, J. C.; Donovan, T. C.; Lee, H. P.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2014, 28, 2, pp 443-450
Abstract

Adrenalectomy is a surgical method of removing one or both adrenal glands that is chosen in cases of adrenal neoplasms and the consequent hyperadrenocorticism Three approaches are described: ventral median, lateral and laparoscopic. Adrenal neoplasms can be divided into adrenal carcinomas, adrenal...

Author(s)
Domančić, M. D. V.
Publisher
Hrvatska Veterinarska Komora, Zagreb, Croatia
Citation
Hrvatski Veterinarski Vjesnik, 2020, 28, 3, pp 29-35
Abstract

Background: Treatment of adrenal-dependent hyperadrenocorticism (ADH) involves either surgical resection of the adrenal tumor or medical therapy. For many years, mitotane has been considered the medical treatment of choice for dogs with ADH. Objectives: The aim of this study was to determine...

Author(s)
Arenas, C.; Melián, C.; Pérez-Alenza, M. D.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2014, 28, 2, pp 473-480
Abstract

Objective - To evaluate the effects of mitotane administration on the function and morphology of pituitary corticotrophs in clinically normal dogs. Animals - 12 clinically normal adult Beagles. Procedures - Dogs were randomly assigned to the control group or the mitotane treatment group. In ...

Author(s)
Taoda, T.; Hara, Y.; Takekoshi, S.; Itoh, J.; Teramoto, A.; Osamura, R. Y.; Tagawa, M.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2006, 67, 8, pp 1385-1394
Abstract

A retrospective study was conducted to determine the factors that might influence the survival in dogs with adrenal-dependent hyperadrenocorticism (ADH) medically managed with either trilostane or mitotane. Clinical data were analysed for all dogs with ADH diagnosed at 4 participating referral...

Publisher
Advanstar Communications Inc, Duluth, USA
Citation
Veterinary Medicine, 2011, 106, 7, pp 328-329
AbstractFull Text

A 5-year-old, Terrier breed dog having the complaints of anestrus, polyuria, polydipsia and alopecia referred to Small Animal Veterinary Teaching Hospital. Paraclinical and clinical assessments confirmed the diagnosis of pituitary-dependent hyperadrenocorticism and Mitotane (25 mg/kg BID 5 days)...

Author(s)
Çolakoğlu, E. Ç.; Haydardedeoğlu, A. E.; Alİhosseİnİ, H.; Kurtdede, A.
Publisher
Kafkas Üniversitesi, Veteriner Fakültesi Dergisi, Kars, Turkey
Citation
Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 2015, 21, 1, pp 135-137
Abstract

We report a case of pituitary-dependent hyperadrenocorticism in a 10-year-old, female, terrier dog. The animal was admitted due to polyphagia, weight gain, polyuria, polydipsia, hair loss, exercise intolerance and panting at rest. On physical examination, abdominal distention, truncal and...

Author(s)
Rezaei, M.; Rostami, S.; Saberi, M.; Vosugh, D.
Publisher
Journal of Coastal Life Medicine, Haikou, China
Citation
Journal of Coastal Life Medicine, 2016, 4, 6, pp 502-504
Abstract

Background: Trilostane is a recognized treatment for canine pituitary-dependent hyperadrenocorticism (PDH); however, its efficacy in dogs with adrenal-dependent hyperadrenocorticism (ADH) is unknown. Objectives: To examine factors that might influence survival in the medical management of ADH, with ...

Author(s)
Helm, J. R.; McLauchlan, G.; Boden, L. A.; Frowde, P. E.; Collings, A. J.; Tebb, A. J.; Elwood, C. M.; Herrtage, M. E.; Parkin, T. D. H.; Ramsey, I. K.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2011, 25, 2, pp 251-260

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