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Abstract

Background: The American Heartworm Society currently recommends the use of a monthly macrocyclic lactone, a 28-day course of 10 mg/kg doxycycline BID, and the 3-dose protocol of melarsomine dihydrochloride for the treatment of canine heartworm disease. Doxycycline is necessary for the reduction of...

Author(s)
Savadelis, M. D.; Day, K. M.; Bradner, J. L.; Wolstenholme, A. J.; Dzimianski, M. T.; Moorhead, A. R.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2018, 11, 671, pp (27 December 2018)
Abstract

Background: Minocycline has been used in the treatment of Ehrlichia canis infection in dogs as an alternative to doxycycline, the recommended treatment. However, efficacy of this alternative therapy is unknown. Objective: To assess the efficacy of minocycline in the treatment of natural occurring ...

Author(s)
Jenkins, S.; Ketzis, J. K.; Dundas, J.; Scorpio, D.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2018, 32, 1, pp 217-221
Abstract

Background: Doxycycline has been considered the first drug of choice for treating Wolbachia, a member of the Rickettsiaceae, which has a symbiotic relationship with filarial worms, including heartworms. Wolbachia, is susceptible to tetracyclines, which have been used as adjunctive treatments for...

Author(s)
Papich, M. G.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2017, 10, Suppl. 2, pp (9 November 2017)
Abstract

Calcinosis cutis is a chronic condition characterized by insoluble calcified deposits in the skin and subcutaneous tissue. Although there is no uniformly effective treatment for calcinosis cutis, minocycline therapy has demonstrated varying degrees of benefit in humans. Five client-owned dogs with...

Author(s)
Cho DaeHee; Lee WangHui; Park SeongJun
Publisher
Korean Society of Veterinary Clinics, Seoul, Korea Republic
Citation
Journal of Veterinary Clinics, 2017, 34, 2, pp 119-122
Abstract

Sucralfate and minocycline may be administered concurrently to dogs. The relative bioavailability of tetracyclines may be reduced if administered with sucralfate, but studies confirming these interactions in dogs are not available. This study evaluated the pharmacokinetics of oral minocycline in ...

Author(s)
Kukanich, K.; Kukanich, B.; Harris, A.; Heinrich, E.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2014, 37, 5, pp 451-456
Abstract

Background: Using the US Clinical and Laboratory Standards Institute (CLSI) human tetracycline breakpoints to predict minocycline and doxycycline susceptibility of Staphylococcus pseudintermedius (SP) isolates from dogs is not appropriate because they are too high to meet...

Author(s)
Hnot, M. L.; Cole, L. K.; Lorch, G.; Papich, M. G.; Rajala-Schultz, P. J.; Daniels, J. B.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Dermatology, 2015, 26, 5, pp e71
Abstract

Background: The effect of food on minocycline oral absorption in dogs is unknown. Objective: The objective was to determine the pharmacokinetics of minocycline after administration of a single oral dose in fed and fasted dogs. Methods: Ten research hounds were administered oral minocycline...

Author(s)
Hnot, M. L.; Cole, L. K.; Lorch, G.; Rajala-Schultz, P. J.; Papich, M. G.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Dermatology, 2015, 26, 6, pp e93
Abstract

Background: Although minocycline is not licensed for use in dogs, this tetracycline has therapeutic potential against meticillin-resistant Staphylococcus pseudintermedius. Hypothesis/Objectives: The aim of this study was to establish rational dosage recommendations for minocycline use in dogs....

Author(s)
Maaland, M. G.; Guardabassi, L.; Papich, M. G.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Dermatology, 2014, 25, 3, pp 182-e47
Abstract

Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is an increasingly important cause of opportunistic infections in dogs and cats. Treatment options are often limited because of the high level of antimicrobial resistance. Doxycycline resistance is common, but variable mechanisms of...

Author(s)
Weese, J. S.; Sweetman, K.; Edson, H.; Rousseau, J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Microbiology, 2013, 162, 2/4, pp 968-971
Abstract

The primary objective of the 2019 Shelter Heartworm Management Practices Survey was to identify the current practices employed for the prevention, diagnosis, and management of heartworm disease in animal shelters. Survey questions were developed to collect the information of interest for dogs,...

Author(s)
DiGangi, B. A.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2020, 282,

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