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Abstract

OBJECTIVE: To determine the physiochemical properties and pharmacokinetics of 3 midazolam gel formulations following buccal administration to dogs. ANIMALS: 5 healthy adult hounds. PROCEDURES: In phase 1 of a 2-phase study, 2 gel formulations were developed that contained 1% midazolam in a...

Author(s)
Aldawsari, M. F.; Lau, V. W.; Babu, R. J.; Arnold, R. D.; Platt, S. R.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2018, 79, 1, pp 73-82
Abstract

Objectives: To determine the frequency, severity and duration of adverse events including myoclonus, pain on injection, hypersalivation, regurgitation and apnoea after administration of midazolam or saline followed by etomidate in hydromorphone premedicated dogs. Materials and Methods: Dogs...

Author(s)
Jones, T. L.; Calbay, R.; Cunha, A. F. da; Hofmeister, E. H.
Publisher
Wiley, Oxford, UK
Citation
Journal of Small Animal Practice, 2021, 62, 6, pp 437-441
Abstract

Background: Midazolam delivered by continuous rate infusion (CRI) might be effective in dogs with cluster seizures (CS) or status epilepticus (SE). Objective: To describe the use and safety of midazolam CRI in dogs with CS or SE. Animals: One-hundred six client-owned dogs presenting to a veterinary ...

Author(s)
Bray, K. Y.; Mariani, C. L.; Early, P. J.; Muñana, K. R.; Olby, N. J.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2020, 35, 1, pp 388-396
AbstractFull Text

Six dogs irrespective of age and sex, categorised as class I or II as per American Society of Anaesthesiologists (ASA) classification, presented to Department of Veterinary Surgery & Radiology for various elective surgeries were selected for this study. All the animals under study were...

Author(s)
Kenjale Lalit; Varghese Reji; Dinesh, P. T.; Sooryadas, S.; Umesh, C. G.
Publisher
Indian Veterinary Association, Kerala, Thiruvananthapuram, India
Citation
Journal of Indian Veterinary Association, Kerala (JIVA), 2022, 20, 2, pp 51-59
Abstract

PICO question: In healthy dogs, does the use of diazepam or midazolam administered in co-induction with propofol result in a reduction in the dose of propofol required to induce anaesthesia and a decrease in adverse cardiovascular and respiratory events? Clinical bottom line: Category of research...

Author(s)
Coward, J. T.; Raillard, M.
Publisher
RCVS Knowledge, London, UK
Citation
Veterinary Evidence, 2022, 7, 2,
Abstract

The purpose of this study was to compare the hemodynamic effects of four different combinations of midazolam and opioids in healthy dogs. Twenty-four healthy dogs were divided in four groups (n = 6) using intramuscular midazolam 0.3 mg/kg and morphine 0.3 mg/kg (GMOR), methadone 0.3 mg/kg (GMET),...

Author(s)
Ferreira, M. de A.; Possidônio, G.; Afonso, C. S.; Ribeiro, I. V.; Moreira, T. F.; Marques, M. G.; Abimussi, C. J. X.; Floriano, B. P.
Publisher
Elsevier Inc, Orlando, USA
Citation
Topics in Companion Animal Medicine, 2022, 46,
Abstract

Objective: To determine the alfaxalone dose reduction during total intravenous anaesthesia (TIVA) when combined with ketamine or midazolam constant rate infusions and to assess recovery quality in healthy dogs. Study design: Prospective, blinded clinical study. Animals: A group of 33 healthy,...

Author(s)
Bustamante, R.; Gómez Segura, I. A. de; Canfrán, S.; Aguado, D.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2020, 47, 4, pp 437-446
Abstract

Objective: To evaluate drug interactions between fluconazole and the intravenous (IV) anesthetic induction agents, ketamine and midazolam. Study design: Randomized parallel study. Animals: A group of 12 adult healthy Beagle dogs. Methods: Dogs were randomly allocated to two groups of six dogs. Dogs ...

Author(s)
Berke, K.; KuKanich, B.; Orchard, R.; Rankin, D.; Joo Hyun
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2019, 46, 6, pp 745-752
Abstract

The purpose of this study was to assess the effects of midazolam combined with morphine or butorphanol on echocardiographic variables of healthy dogs. Twenty-four dogs of various breeds aged 34.33 ± 23.41 months and weighing 8.1 ± 4.7 kg were enrolled in the study. Subjects were randomly allocated...

Author(s)
Possidonio, G.; Santos, C. A.; Ferreira, M. A.; Floriano, B. P.; Almeida, B. F. M. de; Marques, A. E. G. W.; Marques, M. G.
Publisher
Elsevier Inc, Orlando, USA
Citation
Topics in Companion Animal Medicine, 2021, 45,
Abstract

This blinded, randomized, prospective study evaluated the sedative and physiologic effects of a combination of alfaxalone and methadone with or without midazolam in adult dogs. Sixteen dogs received methadone (0.5 mg/kg body weight) and alfaxalone (1 mg/kg body weight), either with or without ...

Author(s)
Micieli, F.; Chiavaccini, L.; Paré, M. D.; Chagas, J. B.; Vesce Giancarlo; Gianotti, G.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Veterinary Journal, 2019, 60, 10, pp 1060-1064

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