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Abstract

This study examines correlations among serum proteins, clinical score, body weight and kidney function biomarkers after a standard treatment course (meglumine antimoniate plus allopurinol) in twelve Canine leishmaniosis (CanL) patients at the three times points pre treatment, after treatment and...

Author(s)
Daza González, M. A.; Miró, G.; Fermín Rodríguez, M.; Rupérez Noguer, C.; Fragío Arnold, C.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2019, 126, pp 131-138
Abstract

Background: Visceral leishmaniosis is a potentially life-threatening illness caused by a protozoan parasite of the genus Leishmania. It is found mainly in areas where both the parasite and its vector are endemic and is one of the most challenging infectious diseases in the world to control. HIV...

Author(s)
Manna, L.; Corso, R.; Galiero, G.; Cerrone, A.; Muzj, P.; Gravino, A. E.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2015, 8, 289, pp (28 May 2015)
Abstract

Canine leishmaniosis (CanL) caused by Leishmania infantum is a zoonotic disease of global concern. Antileishmanial drug therapies commonly used to treat sick dogs improve their clinical condition, although when discontinued relapses can occur. Thus, the current study aims to evaluate the effect of...

Author(s)
Santos, M. F.; Alexandre-Pires, G.; Pereira, M. A.; Marques, C. S.; Gomes, J.; Correia, J.; Duarte, A.; Gomes, L.; Rodrigues, A. V.; Basso, A.; Reisinho, A.; Meireles, J.; Santos-Mateus, D.; Brito, M. T. V.; Tavares, L.; Santos-Gomes, G. M.; Fonseca, I. P. da
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2019, 6, October, pp 362
Abstract

Hepatic fibropoiesis in canine visceral leishmaniasis (CVL) were evaluated by histological (morphometrical collagen deposition) and immunohistochemical assays characterizing alpha-actin (α-SMA), vimentin, calprotectin (L1 antigen), and TGF-β in 46 naturally infected dogs with Leishmania infantum...

Author(s)
Castro, R. S.; Amorim, I. F. G. de; Pereira, R. A.; Silva, S. M.; Pinheiro, L. J.; Pinto, A. J. W.; Azevedo, E. G.; Demicheli, C.; Caliari, M. M. V.; Mosser, D. M.; Michalick, M. S. M.; Frezard, F. J. G.; Tafuri, W. L.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2018, 250, pp 22-29
Abstract

In canine leishmaniosis (CanL), kidneys are affected in virtually all dogs. Treatment of CanL is limited in Europe to meglumine antimoniate and miltefosine. This study evaluated the pharmacological, toxicological, and pathological effects of both drugs in healthy beagle dogs. Four male and four...

Author(s)
Bianciardi, P.; Brovida, C.; Valente, M.; Aresu, L.; Cavicchioli, L.; Vischer, C.; Giroud, L.; Castagnaro, M.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Toxicologic Pathology, 2009, 37, 6, pp 770-775
Abstract

A retrospective study was performed using 53 client owned dogs with leishmaniasis to determine whether the degree of proteinuria, evaluated by the urine protein/creatinine ratio (UP/C), changes following treatment with meglumine antimoniate and allopurinol. Medical records of dogs with...

Author(s)
Pierantozzi, M.; Roura, X.; Paltrinieri, S.; Poggi, M.; Zatelli, A.
Publisher
American Animal Hospital Association, Denver, USA
Citation
Journal of the American Animal Hospital Association, 2013, 49, 4, pp 231-236
Abstract

Introduction: Pentavalent antimony is the first choice drug for leishmaniasis in dog. Leishmaniasis has a complex pathogenesis and it manifests various clinical signs, some of which are often similar to those associated with the toxicity induced by antimonial treatment. Among the reasons for this...

Author(s)
Rambaldi, J.; Barbarossa, A.; Morbidelli, E.; Zaghini, A.
Publisher
Open Learning on Enteric Pathogens (OLOEP), Sassari, Italy
Citation
Journal of Infection in Developing Countries, 2018, 12, 4, pp 279-283
AbstractFull Text

In Canine leishmaniosis (CanL) kidneys are affected in virtually all dogs. Treatment of CanL is limited in Europe to two registered drugs: meglumine antimoniate and miltefosine. This study evaluated the clinical, toxicological and pathological effects of both drugs in eight healthy Beagle dogs...

Author(s)
Bianciardi, P.; Vischer, C.; Brovida, C.; Valente, M.; Aresu, L.; Cavicchioli, L.; Castagnaro, M.
Publisher
Edizioni SCIVAC, Cremona, Italy
Citation
Veterinaria (Cremona), 2009, 23, 4, pp 33-39
Abstract

Leishmania are vector-borne protozoan parasites. Infection with these parasites can result in a range of clinical diseases, dependent upon the infecting species. Leishmania infantum is the main species causing leishmaniosis in dogs and cats in Europe, as well as visceral and cutaneous forms of...

Author(s)
Elsheikha, H.; Wright, I.
Publisher
MA Healthcare Limited, London, UK
Citation
Companion Animal, 2019, 24, Suppl. 3, pp 8-12
Abstract

An 18-month-old intact female crossbred Labrador with four months history of haemorrhagic diarrhoea and vomiting is reported. Histopathological findings on endoscopic biopsies from the stomach, ileum, and colon revealed moderate to severe lymphoplasmatic and histiocytic inflammation with erosion of ...

Author(s)
Ruiz, G.; Laloy, E.; Benchekroun, G.
Publisher
Taylor & Francis, Abingdon, UK
Citation
Veterinary Quarterly, 2015, 35, 4, pp 236-239

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