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Abstract

Insulin glargine 300 U/mL and insulin detemir are synthetic long-acting insulin analogs associated with minimal day-to-day variability or episodes of hypoglycemia in people. Here, 8 healthy purpose-bred dogs each received 2.4 nmol/kg subcutaneous injections of insulin detemir (0.1 U/kg) and insulin ...

Author(s)
Fink, H.; Herbert, C.; Gilor, C.
Publisher
Elsevier Inc, New York, USA
Citation
Domestic Animal Endocrinology, 2018, 64, pp 17-30
Abstract

Objective - To investigate the effects of insulin detemir in dogs with diabetes mellitus. Design - Prospective, uncontrolled clinical trial. Animals - 10 client-owned dogs with naturally occurring diabetes mellitus. Procedures - Dogs were treated with insulin detemir SC every 12 hours for 6 months. ...

Author(s)
Fracassi, F.; Corradini, S.; Hafner, M.; Boretti, F. S.; Sieber-Ruckstuhl, N. S.; Reusch, C. E.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
Journal of the American Veterinary Medical Association, 2015, 247, 1, pp 73-78
Abstract

Insulin detemir is the first member of a new class of long-acting soluble insulin analogues capable of maintaining the basal level of insulin in humans. In this preliminary study, we investigated the time-action profiles of insulin detemir in normal and diabetic dogs since the use of insulin ...

Author(s)
Sako, T.; Mori, A.; Lee, P.; Oda, H.; Saeki, K.; Miki, Y.; Kurishima, M.; Mimura, K.; Nozawa, S.; Mizutani, H.; Makino, Y.; Ishioka, K.; Arai, T.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2011, 90, 3, pp 396-403
Abstract

Diabetes mellitus is a common endocrine disease of dogs and cats. Treatment is mainly based on insulin administration and dietary modifications. The aim of this review is to provide updated information on insulin treatment of dogs and cats with non-complicated diabetes mellitus. During the last...

Author(s)
Saridomichelakis, M. N.; Chatzis, M. K.
Publisher
Hellenic Veterinary Medical Society, Athens, Greece
Citation
Deltion tes Ellenikes Kteniatrikes Etaireias = Journal of the Hellenic Veterinary Medical Society, 2016, 67, 2, pp 83-98
Abstract

Diabetes is often associated with pituitary-dependent hyperadrenocorticism (PDH). Hypercortisolism causes insulin resistance and affects β-cell function. The purpose of this study was to test if daily administration of a long-acting insulin analogue during the first month of anti-PDH treatment can...

Author(s)
Miceli, D. D.; Gallelli, M. F.; Blatter, M. F. C.; Martiarena, B.; Brañas, M. M.; Ortemberg, L. R.; Gómez, N. V.; Castillo, V. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2012, 93, 1, pp 114-120
Abstract

Human recombinant synthetic insulin analogs allow better control of blood glucose concentrations while minimizing the risk of hypoglycemic events in diabetic human patients. Little information is available regarding the use of insulin analogs in cats and dogs. Insulin lispro is an ultrashort-acting ...

Author(s)
Gilor, C.; Graves, T. K.
Publisher
W.B. Saunders, Philadelphia, USA
Citation
Veterinary Clinics of North America, Small Animal Practice, 2010, 40, 2, pp 297-307
Abstract

Monitoring of blood glucose concentration is important to evaluate the diabetic status of dogs. Continuous glucose monitoring systems (CGMS) have been applied in veterinary medicine for glucose monitoring in diabetic dogs. The purpose of the study was to evaluate the daily glycemic profiles...

Author(s)
Mori, A.; Kurishima, M.; Oda, H.; Saeki, K.; Arai, T.; Sako, T.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2013, 75, 1, pp 113-117
Abstract

Polyuria, polydipsia, polyphagia and weight loss are indicative for the presence of diabetes mellitus in dogs and cats. The diagnosis is straightforward: hyperglycaemia and glucosuria are evidentiary if the symptoms mentioned beforehand are present und stress hyperglycaemia can be excluded. The...

Author(s)
Wehner, A.; Geist, S.
Publisher
Verlag M. & H, Schaper Gmbh, Hannover, Germany
Citation
Kleintierpraxis, 2014, 59, 8, pp 443-459

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