Metabolic syndrome, or metabolic dysfunction related to obesity in dogs, is a set of factors that may predispose comorbidities secondary to obesity. Adjuvant therapy with an energy-restricted diet, especially with low levels of carbohydrate and fat, is essential for weight loss, in addition to...

Background: Mammary tumors are the most common type of tumor in female dogs and account for 50% of all tumors in dogs. The clinical prognosis of canine mammary tumors is strongly affected by the size, stages, histological type, and grade of tumor; mitotic index; and nearby and distant metastasis....

Lipid disorders are relatively common in dogs. Hyperlipidemia can be primary or secondary to other diseases. In humans, fenofibrate is used to control hypertriglyceridemia. In dogs, there are no studies evaluating fenofibrate in hypertriglyceridemia. The aim of the study was to evaluate the safety...

The aim of this study was to evaluate the relationship between obesity and adipokines and also to determine subclinical myocardial injury by cardiac biomarkers. Twenty-five healthy obese (HO) and 15 healthy normal weight (HN) mixed breed dogs were enrolled in the study. Blood sampling and...

In several species, intermittent fasting (IF) has been shown to have beneficial effects, including delayed aging, increased lifespan, increased insulin sensitivity, reduced ischemic tissue damage, delayed onset of neurodegenerative disease and improved neuronal repair following injury. However, the ...

Aging is a process that includes natural and time-dependent changes in the body. Dogs whose quality of life is not adversely affected are classified as healthy elderly dogs. Behavioral and cognitive status should be taken into consideration together with blood analyzes in the health evaluation of...

To evaluate the interference of postprandial lipemia on blood gas parameters and to assess the acid-base status by the quantitative approach of the strong ion model blood samples of 15 healthy dogs were collected during fasting (0 h) and at one (1 h), three (3 h) and five (5 h) hours after the...

BACKGROUND: Homocysteine (Hcy) is a sulfur-containing amino acid derived from methionine. Several studies have suggested that plasma Hcy may be a useful biomarker of cardiovascular disease in human. There is limited information about serum homocysteine in heart diseases of dogs. OBJECTIVES: The...

Obesity in dogs is increasingly present in the veterinary practice. In humans, it's known that there is a significant correlation between obesity and the development of hypertension and insulin resistance, a clinical picture called metabolic syndrome. In dogs, however, there is only anecdotal about ...

The measurement of serum sialic acid concentration is of importance to indicate damage in cells or tissues. Dirofilaria immitis causes cardiovascular, pulmonary, hepatic and kidney lesions. Therefore, present study was planned to investigate the potential changes in the levels of serum total sialic ...