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Abstract

Background: Perinuclear antineutrophil cytoplasmic antibodies (pANCA) previously have been shown to be serum markers in dogs with chronic enteropathies, with dogs that have food-responsive disease (FRD) having higher frequencies of seropositivity than dogs with steroid-responsive disease (SRD). The ...

Author(s)
Florey, J.; Viall, A.; Streu, S.; DiMuro, V.; Riddle, A.; Kirk, J.; Perazzotti, L.; Affeldt, K.; Wagner, R.; Vaden, S.; Harris, T.; Allenspach, K.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2017, 31, 4, pp 1062-1066
Abstract

Circulating antinuclear antibodies (ANA) are commonly present in the systemic autoimmune disease Systemic Lupus Erythematosus (SLE) and in other systemic rheumatic diseases, in humans as well as in dogs. The indirect immunofluorescence (IIF)-ANA test is the standard method for detecting ANA....

Author(s)
Bremer, H. D.; Lattwein, E.; Renneker, S.; Lilliehöök, I.; Rönnelid, J.; Hansson-Hamlin, H.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2015, 168, 3/4, pp 233-241
Abstract

This case report describes the clinical presentation, diagnosis and management of marked eosinophilic polysynovitis in a five-year-old male neutered kelpie dog. The dog was referred following a three-month history of multifocal lameness and intermittent fever that was unresponsive to NSAIDs or...

Author(s)
Birckhead, A.; Combs, M.; Croser, E.; Jermyn, K.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record Case Reports, 2019, 7, 1, pp e000763
AbstractFull Text

Nova Scotia Duck Tolling Retrievers (NSDTRs) are a dog breed often affected by immune-mediated rheumatic disease (IMRD), a disorder characterised by chronic stiffness and joint pain. Most, but not all, dogs with IMRD, have antinuclear antibodies (ANA), which are also commonly present in the...

Author(s)
Bremer, H. D.; Hillström, A.; Kånåhols, M.; Hagman, R.; Hansson-Hamlin, H.
Publisher
BioMed Central Ltd, London, UK
Citation
Acta Veterinaria Scandinavica, 2017, 59, 21, pp (17 April 2017)
Abstract

The senile female dog suffering from rheumatoid arthritis was clinically and clinicopathologically examined. The articular lesions localized in the elbows, stifles, and the carpal and tarsal joints. The dog with clinical signs of arthritis developed draining nodular lesions in the involved joints....

Author(s)
Kimura, T.
Publisher
PAGEPress Publications, Pavia, Italy
Citation
Veterinary Science Development, 2017, 7, 1, pp 6463
Abstract

Background: Immune-modulating drugs show limited therapeutic efficacy in canine exfoliative cutaneous lupus erythematosus (ECLE); over half of ECLE dogs are eventually euthanized for their lack of response to therapy. Objective: To describe a case of generalized ECLE in a dog in which mycophenolate ...

Author(s)
Ferrigno, A.; Hoover, K.; Blubaugh, A.; Rissi, D.; Banovic, F.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Dermatology, 2019, 30, 4, pp 350-e102
Abstract

In recent years, serologic markers for diagnosis and classification of inflammatory bowel disease (IBD) have been used in human medicine. Perinuclear, antineutrophil, cytoplasmic antibodies (p-ANCA) are the most important of these markers. Because of their similar pattern of fluorescence, ...

Author(s)
Mancho, C.; Sainz, Á.; García-Sancho, M.; Villaescusa, A.; Tesouro, M. A.; Rodríguez-Franco, F.
Publisher
American Association of Veterinary Laboratory Diagnosticians, Davis, USA
Citation
Journal of Veterinary Diagnostic Investigation, 2010, 22, 4, pp 553-558
Abstract

A modified indirect immunofluorescence method, using rat liver as substrate, was developed to determine the immunoglobulin isotypes forming antinuclear antibodies in sera from 12 antinuclear antibody-positive dogs out of 121 dogs with natural leishmania infection. IgM antinuclear antibodies were...

Author(s)
Lucena, R.; Ginel, P. J.
Citation
Research in Veterinary Science, 1998, 65, 3, pp 205-207
Abstract

Specific immune reaction to the own antigens of the organism is the basis of autoimmunity. The immuno-pathological process, resulting in the onset of non-regulated immune response to auto-antigens, is considered as autoimmunity. In these cases the cells and tissues carrying a given antigen stop...

Author(s)
Fialkovičová, M.; Pistl, J.; Karasová, M.; Polláková, J.
Publisher
Institute for Postgraduate Education of Veterinary Surgeons, Košice, Slovakia
Citation
Slovenský Veterinársky Časopis, 2011, 36, 1, pp 24-26
Abstract

Background: Immune system involvement is suggested as an underlying cause for Doberman hepatitis (DH) based on female predisposition, lymphocyte infiltration, abnormal hepatocyte expression of major histocompatibility complex class II antigens, and homozygosity for dog leukocyte antigen DRB1*00601. ...

Author(s)
Dyggve, H.; Meri, S.; Spillmann, T.; Jarva, H.; Speeti, M.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2017, 31, 6, pp 1717-1723

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