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Abstract

Blastomycosis is a systemic fungal disease of humans and other animals produced by the thermally dimorphic fungal organism, Blastomyces dermatitidis. Recent studies have focused on the utilization of antibody and antigen detection in the development of immunoassays for the diagnosis of...

Author(s)
Hammon, J. T.; Kennell, B. C.; Scalarone, G. M.
Publisher
Springer, Dordrecht, Netherlands
Citation
Mycopathologia, 2019, 184, 5, pp 661-666
Abstract

Objective - To evaluate the sensitivity and specificity of an enzyme immunoassay (EIA) for antibodies to a recombinant Blastomyces adhesin-1 repeat antigen (rBAD-1) to aid in the diagnosis of blastomycosis in dogs and compare the findings with results from other tests used for this purpose. Design...

Author(s)
Mourning, A. C.; Patterson, E. E.; Kirsch, E. J.; Renschler, J. S.; Wolf, L. A.; Paris, J. K.; Durkin, M. M.; Wheat, L. J.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
Journal of the American Veterinary Medical Association, 2015, 247, 10, pp 1133-1138
Abstract

Background: Hypovitaminosis D is common in humans with tuberculosis, and adequate serum 25-hydroxyvitamin D [25(OH)D] concentrations may improve response to therapy. The pathomechanism of Blastomyces dermatitidis is similar to that of Mycobacterium tuberculosis, but the 25(OH)D status of dogs with...

Author(s)
O'Brien, M. A.; McMichael, M. A.; Boedec, K. le
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2018, 32, 5, pp 1684-1691
AbstractFull Text

Blastomycosis and histoplasmosis manifest as lung and systemic fungal infections in mammals caused by Histoplasma capsulatum, and Blastomyces dermatitidis. These infections exhibit cross reactivity of antibodies which makes a correct diagnosis potentially elusive. The purpose of this study was to...

Author(s)
Wright, J. C.; Harrild, T. E.; Scalarone, G. M.
Publisher
Scientific Research Publishing, Irvine, USA
Citation
Open Journal of Veterinary Medicine, 2012, 2, 4, pp 237-241
Abstract

Background: Several studies have shown that Blastomyces dermatitidis, the etiologic agent of blastomycosis, is a genetically diverse pathogen. Blastomycosis is a significant health issue in humans and other mammals. Veterinary and human isolates matched with epidemiological case data from the same...

Author(s)
Anderson, J. L.; Sloss, B. L.; Meece, J. K.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2013, 9, 84, pp (22 April 2013)
Abstract

Dogs are common hosts to the fungal organism Blastomyces dermatitidis, which causes the systemic disease blastomycosis. The goal of our study was to compare the reactivity of two B. dermatitidis yeast lysate antigens prepared from dog isolates (ERC-2, Wisconsin; T-58, Tennessee) and two lysate...

Author(s)
Mondada, K.; Fullmer, J.; Hungerford, E.; Novack, K.; Vickers, K.; Scalarone, G.
Publisher
Hindawi Publishing Corporation, New York, USA
Citation
Veterinary Medicine International, 2014, 2014, pp Article ID 376725
AbstractFull Text

Meningoencephalitis (ME) is a common inflammatory disorder of the central nervous system in dogs. Clinically, ME has both infectious and non-infectious causes. In the present study, a multiplex quantitative real-time polymerase chain reaction (mqPCR) panel was optimized for the detection of eight...

Author(s)
Han JaeIk; Chang DongWoo; Na KiJeong
Publisher
Korean Society of Veterinary Science, Seoul, Korea Republic
Citation
Journal of Veterinary Science, 2015, 16, 3, pp 341-347
Abstract

The systemic fungal infection, blastomycosis, which infects both humans and animals has presented a diagnostic challenge for clinicians for many years. The aim of this study was to evaluate the diagnostic sensitivity of Blastomyces dermatitidis yeast lysate antigens with respect to antibody...

Author(s)
Boyd, A. R.; VanDyke, J. L.; Scalarone, G. M.
Publisher
Hindawi Publishing Corporation, New York, USA
Citation
Veterinary Medicine International, 2013, 2013, pp Article ID 940126
Abstract

The nasal cavities of domestic animals may concentrate and allow isolation of environmentally acquired fungal pathogens. We obtained two swabs each from the nares of 110 asymptomatic, physically normal dogs from a veterinary practice in Eagle River, WI, USA, an area highly endemic for...

Author(s)
Varani, N.; Baumgardner, D. J.; Czuprynski, C. J.; Paretsky, D. P.
Publisher
Informa Healthcare, London, UK
Citation
Medical Mycology, 2009, 47, 7, pp 780-782
Abstract

This was a retrospective case study of eight dogs diagnosed with prostatic or testicular B. dermatitidis infection. Signalment, clinical presentation, diagnostic procedures, and treatment options were evaluated. Review of medical records of dogs diagnosed with blastomycosis at the University of...

Author(s)
Totten, A. K.; Ridgway, M. D.; Sauberli, D. S.
Publisher
American Animal Hospital Association, Denver, USA
Citation
Journal of the American Animal Hospital Association, 2011, 47, 6, pp 413-418

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