Background: The guaiac-based fecal occult blood test (gFOBt) has been used for human colorectal cancer screening. It can detect the fecal occult blood (FOB) in dogs after oral administration of 20 mg of hemoglobin/kg body weight of blood and is influenced by diet. Objectives: The aims were to...
Author(s)
Pierini, A.; Bartoletti, F.; Lubas, G.; Gori, E.; Marchetti, V.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2020, 49, 1, pp 71-77
Background: The risk of occult gastrointestinal bleeding (OGIB) is known to be increased among human dialysis patients suffering from end-stage renal disease. However, there are no studies to date that investigate the incidence of OGIB in either dogs or people with chronic kidney disease (CKD),...
Author(s)
Crivellenti, L. Z.; Borin-Crivellenti, S.; Fertal, K. L.; Contin, C. M.; Miranda, C. M. J.; Santana, A. E.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2017, 46, 1, pp 132-137
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Advances in Small Animal Medicine and Surgery, 2020, 33, 10, pp 4-4
Introduction: Combining an antiplatelet drug, clopidogrel, with the direct oral Factor Xa inhibitor, apixaban, could provide an effective antithrombotic strategy in dogs. Thus, a limited 3 + 3 phase I dose-escalation clinical trial in healthy dogs was conducted to evaluate bleeding (primary...
Author(s)
Gagnon, A. L.; Scansen, B. A.; Olver, C.; Shropshire, S.; Hess, A.; Orton, E. C.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Veterinary Cardiology, 2021, 36, pp 105-114
This study was undertaken to investigate whether the concentration of carbonic anhydorase isoenzyme I (CA-I) in canine faeces and urine is useful as a temporary marker of occult blood. Concentrations of CA-I were measured by enzyme-linked immunosorbent assay (ELISA). Faecal CA-I concentrations in...
Author(s)
Iguchi, K.; Kawato, K.; Seita, T.; Kuribayashi, T.; Shimada, T.; Matsumoto, M.; Yamamoto, Y.; Yamada, M.; Yamamoto, S.
Publisher
Japanese Association for Laboratory Animal Science, Tokyo, Japan
Citation
Experimental Animals, 2007, 56, 1, pp 43-49
Despite the extensive application of nonsteroidal anti-inflammatory drugs (NSAIDs), the use of these drugs is limited due to their adverse effects especially on gastric mucosa. Dual inhibitors that inhibit both cyclooxygenase (COX) and lipoxygenase (LOX) metabolites are considered to have less...
Author(s)
Tabrizi, A. S.; Azizzadeh, M.; Esfandiari, A.
Publisher
PAGEPress Publications, Pavia, Italy
Citation
Veterinary Science Development, 2017, 7, 1, pp 6245
This study was undertaken to investigate whether the concentration of carbonic anhydorase isoenzyme I (CA-I) in canine faeces and urine is useful as a temporary marker of occult blood. Concentrations of CA-I were measured by enzyme linked immunosorbent assay (ELISA). The reactivity of canine CA-I...
Author(s)
Yamamoto, S.; Kuribayashi, T.; Honda, M.
Publisher
Azabu University, Sagamihara, Japan
Citation
Journal of Azabu University, 2007, 15/16, pp 267-273
The interaction between oral non-steroidal anti-inflammatory drugs (NSAIDs) and prednisolone administered concurrently for 30 days was studied in 18 healthy dogs divided into 3 groups of 6 dogs each: a drug-free negative control group (NC group) given 2 gelatin capsules; a group given meloxicam...
Author(s)
Narita, T.; Sato, R.; Motoishi, K.; Tani, K.; Naito, Y.; Hara, S.
Publisher
Japanese Society of Veterinary Science, Tokyo, Japan
Citation
Journal of Veterinary Medical Science, 2007, 69, 4, pp 353-363
Background: Daxocox® [Ecuphar/Animalcare Group] contains the selective COX-2 inhibitor enflicoxib, approved in the EU for the treatment of pain and inflammation associated with osteoarthritis in dogs. The safety of Daxocox® was evaluated in a target animal safety study: Groups of 4 dogs per sex...
Author(s)
Homedes, J.; Salichs, M.; Guzman, A.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2021, 17, 205, pp (3 June 2021)
Six dogs were fed each of 9 diets to evaluate the effects of diet on faecal occult blood test results. The diets represented a range of different type (canned, dry or semi-moist), protein and vegetable constituents, and fibre contents. Each diet was fed twice daily for 5 consecutive days; faecal...
Author(s)
Rice, J. E.; Ihle, S. L.
Citation
Canadian Journal of Veterinary Research, 1994, 58, 2, pp 134-137