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Abstract

In our previous study, we demonstrated that the repair efficiency of DNA double-strand breaks declines with increasing age in rat primordial follicles. In the present study, we extended our studies to buffalo (Bubalus bubalis) wherein we studied the expression of BRCA-1 related DNA repair genes in...

Author(s)
Vijayakumar Govindaraj; Harshini Krishnagiri; Chauhan, M. S.; Rao, A. J.
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2017, 28, 2, pp 94-103
Abstract

To test the hypothesis that increased circulating estradiol increases hepatic glutamine synthetase (GS) content in young and aged cows, and two nonclassical nongenomic estradiol pathway intermediates [β-catenin, G protein-coupled receptor 30 (GPR30)], 12 young (3-4 yr) and 12 aged (≥8 yr) cows were ...

Author(s)
Miles, E. D.; McBride, B. W.; Bridges, P. J.; Matthews, J. C.
Publisher
NRC Research Press, Ottawa, Canada
Citation
Canadian Journal of Animal Science, 2017, 97, 2, pp 281-289
Abstract

Background: Autophagy is a highly regulated process involving the bulk degradation of cytoplasmic macromolecules and organelles in mammalian cells via the lysosomal system. Dysregulation of autophagy is implicated in the pathogenesis of many neurodegenerative diseases and integrity of the...

Author(s)
Biase, D. de; Costagliola, A.; Pagano, T. B.; Piegari, G.; Wojcik, S.; Dziewiątkowski, J.; Grieco, E.; Raso, G. M.; Russo, V.; Papparella, S.; Paciello, O.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2017, 13, 102, pp (13 April 2017)
Abstract

The study on 919 rural Murrah adult buffaloes aging between 39 to 89 months belonging to 846 farmers spread in 555 villages of 5 districts in Uttar Pradesh was conducted to estimate body surface area (BSA) using 2D photographic image by digital camera and using computer software BIOVIS PSM_L1000....

Author(s)
Gokhale, S. B.; Shirsath, T. V.; Sonawane, D. R.; Shinde, D. N.
Publisher
Indian Council of Agricultural Research, New Delhi, India
Citation
Indian Journal of Animal Sciences, 2017, 87, 6, pp 775-777
Abstract

Background: Understanding gene expression changes over lifespan in diverse animal species will lead to insights to conserved processes in the biology of aging and allow development of interventions to improve health. Rotifers are small aquatic invertebrates that have been used in aging studies for...

Author(s)
Gribble, K. E.; Welch, D. B. M.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2017, 18, 217, pp (1 March 2017)
Abstract

Scope: Studies suggest diets rich in fruit and vegetables reduce bone loss, although the specific compounds responsible are unknown. Substrates for endogenous nitric oxide (NO) production, including organic nitrates and dietary nitrate, may support NO production in age-related conditions, including ...

Author(s)
Conley, M. N.; Roberts, C.; Sharpton, T. J.; Iwaniec, U. T.; Hord, N. G.
Publisher
Wiley, Weinheim, Germany
Citation
Molecular Nutrition & Food Research, 2017, 61, 5, pp 1600372
Abstract

Prevention of Alzheimer's disease (AD) is a major goal of biomedical sciences. In previous studies we showed that high intake of the essential nutrient, choline, during gestation prevented age-related memory decline in a rat model. In this study we investigated the effects of a similar treatment on ...

Author(s)
Mellott, T. J.; Huleatt, O. M.; Shade, B. N.; Pender, S. M.; Liu, Y. B.; Slack, B. E.; Blusztajn, J. K.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2017, 12, 1, pp e0170450
Abstract

Developmental and aging changes in testicular factors related to steroidogenesis are unknown in dogs. Using reverse transcription quantitative real-time PCR, this study examined testicular mRNA levels of CYP11A1 (P450 cholesterol side-chain cleavage enzyme, P450scc), CYP17A1 (P450...

Author(s)
Ogawa, E.; Kawate, N.; Inaba, T.; Tamada, H.
Publisher
Elsevier, New York, USA
Citation
Theriogenology, 2017, 90, pp 42-48
Abstract

Parkinson's disease (PD) is an age-related neurological disorder characterized by a loss of dopaminergic neurons within the midbrain. Neuroinflammation has been nominated as one of the key pathogenic features of PD. Recently, the inadequate pharmacotherapy and adverse effects of conventional drugs...

Author(s)
Sandeep More; Choi DongKug
Publisher
MDPI AG, Basel, Switzerland
Citation
Nutrients, 2017, 9, 5, pp 451
Abstract

Background: Modern imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI) have the advantage of producing images without superimposition. Whilst CT is a well-established technique for dental diagnostics, MRI examinations are rarely used for the evaluation of dental ...

Author(s)
Schoppe, C.; Hellige, M.; Rohn, K.; Ohnesorge, B.; Bienert-Zeit, A.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2017, 13, 280, pp (6 September 2017)

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