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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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A method for assessing the cross-vaccinating dose 50 (CVD50) in g.pigs is described. By this technique it is possible to differentiate variants, which it is not possible to do in a statistically significant manner by the qualitative test in cattle. It is possible to express, by coefficients, the...

Fontaine, J.; Terre, J.; Roumiantzeff, M.; Dubouclard, C.; Bornarel, P.; Favre, H.
Societe des Sciences Veterinaires de Lyon, Lyon, France
Bulletin de la Societe des Sciences Veterinaires de Lyon, 1966, 68, pp 161-172

The method, for monovalent vaccines, consists in: vaccinating cattle with varying doses; administering challenge dose-criterion of protection being absence of secondary foot lesions up to 5 days after challenge; and estimation of the D50, by Litchfield's method. Thus, the efficacy of a vaccine can...

Terré, J.; Bornarel, P.; Stellmann, C.; Soulebot, J.
Recueil de Medecine Veterinaire, 1965, 141, pp 1109-1130