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Abstract

The test was performed by a micro-method, using g.pig hyperimmune serum and virus antigen of high titre produced in tissue culture Two hours at room temp. or one hour at 37°C gave the best results. The test was suitable for measuring the antibody response to a vaccine.-RM.

Author(s)
Roumiantzeff, M.; Salvatori, J.; CaillèRe, F.
Citation
Recueil de Medecine Veterinaire, 1969, 145, pp 455-463
Abstract

It is concluded that g.-pigs are suitable for assay provided they weigh about 500 g. each, are in good health, come from known breeding establishments and are kept under constant conditions of husbandry during experiments. A good immune response was elicited by i/m injection; antibody titres...

Author(s)
Mackowiak, C.; Lang, R.; Petermann, H. G.; Roumiantzeff, M.; Fontaine, J.; Stellman, C.
Publisher
Institut de la Fièvre Aphteuse, Lyon.,
Citation
Revue de Medicine Veterinaire, 1965, 116, pp 497-507
Abstract

It is concluded that g.-pigs are suitable for assay provided they weigh about 500 g. each, are in good health, come from known breeding establishments and are kept under constant conditions of husbandry during experiments. A good immune response was elicited by i/m injection; antibody titres...

Author(s)
Roumiantzeff, M.; Fontaine, J.; Stellman, C.; Mackowiak, C.
Publisher
Institut de la Fièvre Aphteuse, Lyon.,
Citation
Revue de Medicine Veterinaire, 1965, 116, pp 597-607
Abstract

It is concluded that g.-pigs are suitable for assay provided they weigh about 500 g. each, are in good health, come from known breeding establishments and are kept under constant conditions of husbandry during experiments. A good immune response was elicited by i/m injection; antibody titres...

Author(s)
Stellmann, C.; Terre, J.; Roumiantzeff, M.; Bornarel, P.
Publisher
Institut de la Fièvre Aphteuse, Lyon.,
Citation
Revue de Medicine Veterinaire, 1965, 116, pp 609-615
Abstract

A method for assessing the cross-vaccinating dose 50 (CVD50) in g.pigs is described. By this technique it is possible to differentiate variants, which it is not possible to do in a statistically significant manner by the qualitative test in cattle. It is possible to express, by coefficients, the...

Author(s)
Fontaine, J.; Terre, J.; Roumiantzeff, M.; Dubouclard, C.; Bornarel, P.; Favre, H.
Publisher
Societe des Sciences Veterinaires de Lyon, Lyon, France
Citation
Bulletin de la Societe des Sciences Veterinaires de Lyon, 1966, 68, pp 161-172
Abstract

According to results of cross immunity tests on cattle the "Flanders" and the "Spain 64" strains cannot be regarded as true variants, although differences in immunogenicity were observed. It is considered that in studies on variants quantitative methods should be used exclusively. Under present...

Author(s)
Fontaine, J.; Gayot, G.; Dubouclard, C.; Dhennin, Leone; Roumiantzeff, M.; Terre, J.; Dhennin, Louis
Publisher
Office International des Epizooties, Paris, France
Citation
Bulletin de l'Office International des Epizooties, 1966, 65, pp 2051-2062
Abstract

The authors discussed in detail the culture technique employed at the Foot and Mouth Disease Intitute, Lyon, and elsewhere (38 references). In the 'multiculture' method the first stage of culture is terminated after 14-20 hours (depending on the strain of virus). The medium is changed and...

Author(s)
Mackowiak, C.; Dubouclard, C.; Favre, H.; Roumiantzeff, M.; Fontaine, J.; Terré, J.; Bornarel, P.
Publisher
Office International des Epizooties, Paris, France
Citation
Bulletin de l'Office International des Epizooties, 1969, 71, pp 3-45
Abstract

This method eliminates the permanent focus of infection created by infected cattle; it is of value for studies of the different factors of virus multiplication; it requires relatively simple equipment and enables large-scale production of vaccine in case of epidemics caused by new strains of the...

Author(s)
Dubouclard, C.; Roumiantzeff, M.; Fontaine, J.; Mackowiak, C.
Publisher
Societe des Sciences Veterinaires de Lyon, Lyon, France
Citation
Bulletin de la Societe des Sciences Veterinaires de Lyon, 1966, 68, pp 243-253
Abstract

The method of growing F & M disease virus on bovine tongue epithelium cultures [see V.B. 37, abst. 1233] gave insufficient yield of virus. Replacement of the first tissue culture fluid by a second equal volume was shown to increase the yield. Reasons for this are discussed.-RRS.

Author(s)
Dubouclard, C.; Roumiantzeff, M.; Fontaine, J.; Mackowiak, C.
Citation
Bulletin de l'Academie Veterinaire de France, 1968, 41, pp 251-258

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