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Abstract

Theileria parva causes acute, usually fatal, disease of cattle characterized by widespread parasitism and destruction of cells of the lymphoid system. Animals which recover from infection are immune to challenge with the homologous stock of the parasite. Immunity can also be induced by various...

Author(s)
Morrison, W. I.; Emery, D. L.; Teale, A. J.; Goddeeris, B. M.
Publisher
Cambridge University Press, Cambridge, UK
Citation
The ruminant immune system in health and disease., 1986, pp 555-570
Abstract

Author(s)
Emery, D. L.; Morrison, W. I.; Eugui, E. M.
Publisher
Plenum Press, New York, USA
Citation
The ruminant immune system. (Proc. Internat. Symp., 7-10 July 1980, Plymouth, New Hampshire.) (Advances in experimental medicine and biology, Vol. 137), 1981, pp 834
Abstract

Protection against challenge with T. parva was conferred on 3 of 4 calves given 3 or 4 inocula of plasma membranes prepared from a total of 6 to 12 × 105 autologous parasitized lymphoblasts from cultured cell lines. In contrast, calves remained susceptible to infection following immunization with...

Author(s)
Emery, D. L.; Morrison, W. I.; Jack, R. M.
Citation
Veterinary Parasitology, 1986, 19, 3/4, pp 321-327
Abstract

Examination of the specificity of cytotoxicity generated in vitro and in vivo against infected bovine lymphocytes revealed that cytotoxic T lymphocytes (CTL) obtained from cattle immune to T. parva recognized parasite-induced alterations associated with major histocompatibility complex antigens on...

Author(s)
Emery, D. L.; Kar, S. K.
Citation
Immunology, 1983, 48, 4, pp 723-731
Abstract

The participation of genetically restricted cell-mediated lympholysis (CML) in protective immunity against Theileria parva was examined in cattle inoculated with autologous and allogeneic parasitized lymphoblasts. Most cattle given 107 infected allogeneic cells were protected against infection with ...

Author(s)
Emery, D. L.; Morrison, W. I.; Buscher, G.; Nelson, R. T.
Citation
Journal of Immunology, 1982, 128, 1, pp 195-200
Abstract

During the course of a lethal infection with T. parva in susceptible cattle the dissemination of the parasite was examined in central lymph efferent from superficial lymph nodes in the thoracic duct. Lymphocytes containing macroschizonts were detected in efferent lymph from the regional node 8 days ...

Author(s)
Emery, D. L.
Citation
Veterinary Parasitology, 1981, 9, 1, pp 1-16
Abstract

During the course of East Coast Fever (ECF) in cattle, due to Theileria parva, an examination was made of the development of autologous mixed leucocyte reactions (MLR) between normal responder lymphocytes collected before infection and stimulator cells prepared from infected lymphoid organs at...

Author(s)
Emery, D. L.; Morrison, W. I.
Citation
Immunology, 1980, 40, 2, pp 229-237
Abstract

Resistance to a lethal challenge with Theileria parva (Muguga) was transferred between 2 pairs of chimeric bovine co-twins with 5 to 9 X 1010 syngeneic thoracic duct leucocytes from the immunized partner. In one recipient, the infection became established and was eliminated. In the 2nd recipient,...

Author(s)
Emery, D. L.
Citation
Research in Veterinary Science, 30, 3, pp 364-367
Abstract

Leukocytes from cattle with lethal or sublethal infections with T. parva were examined for responses in autologous mixed lymphocyte reactions (MLR) and for specific and nonspecific cytotoxicity against cultured cell lines. During lethal infections, lymphoblasts isolated from central lymph from days ...

Author(s)
Emery, D. L.; Eugui, E. M.; Nelson, R. T.; Tenywa, T.
Citation
Immunology, 43, 2, pp 323-336
Abstract

The peripheral blood leucocytes of cattle immunized against Theileria parva were fractionated and depleted. Judging by the results, the effector cells, which mediated cytotoxicity against parasitized autologous lymphocytes, were considered to be thymus-derived lymphocytes.

Author(s)
Emery, D. L.; Tenywa, T.; Jack, R. M.
Citation
Infection and Immunity, 32, 3, pp 1301-1304

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