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Abstract

An overview of the chemotherapy research programme against trypanosomiasis undertaken at the International Laboratory for Research on Animal Diseases in Kenya, is given. Work carried out is grouped under the following 8 broad topics: development of in vitro culture techniques for identifying and...

Author(s)
Peregrine, A. S.; Sutherland, I. A.; Mutharia, L.; Jamnadass, R.; Gray, M. A.; Codjia, V.; Aliu, Y. O.; Mamman, M.; Silayo, R.; D'Ieteren, G. D. M.; Moloo, S. K.; Murphy, N. B.
Publisher
International Laboratory for Research on Animal Diseases, Nairobi, Kenya
Citation
Chemotherapy for trypanosomiasis. Proceedings of a workshop held at ILRAD, Nairobi, Kenya, 21-24 August, 1989., 1990, pp 3-8
Abstract

Four Boran cattle were infected with Trypanosoma brucei using Glossina morsitans centralis and were left untreated throughout the experimental period of 18 months. During this period, sequential blood samples were collected and examined for the presence of antitrypanosome antibodies and their...

Author(s)
Masake, R. A.; Moloo, S. K.; Nantulya, V. M.; Minja, S. H.; Makau, J. M.; Njuguna, J. T.
Citation
Veterinary Parasitology, 1995, 56, 1/3, pp 37-46
Abstract

5 cattle were treated intramuscularly with isometamidium chloride at a dose rate of 0.5mg/kg body weight (bw) and challenged 28 days later with 5 Glossina morsitans centralis infected with T. congolense IL 3580 (a clone which exhibits a low level of resistance to isometamidium chloride). All 5 ...

Author(s)
Sutherland, I. A.; Codjia, V.; Moloo, S. K.; Holmes, P. H.; Peregrine, A. S.
Citation
Tropical Animal Health and Production, 1992, 24, 3, pp 157-163
Abstract

Author(s)
Williams, D. J. L.; Naessens, J.; Moloo, S. K.; Scott, J. R.
Citation
Publication - International Scientific Council for Trypanosomiasis Research and Control, 1991, No.115, pp 152-161
Abstract

Author(s)
Sutherland, I. A.; Moloo, S. K.; Holmes, P. H.; Peregrine, A. S.
Citation
Publication - International Scientific Council for Trypanosomiasis Research and Control, 1991, No.115, pp 514-515
Abstract

Glossina morsitans centralis were fed on the flanks of African buffalo, N'Dama or Boran cattle from Kenya, experimentally infected with T. vivax IL 2337. The infected tsetse were maintained on goats and on day 25 after the infected feed, the surviving tsetse were dissected to determine the...

Author(s)
Moloo, S. K.; Gettinby, G.; Olubayo, R. O.; Kabata, J. M.; Okumu, I. O.
Citation
Parasitology, 1993, 106, 3, pp 277-282
Abstract

Author(s)
Peregrine, A. S.; Fasogbon, A. I.; Scott, J.; Knowles, G.; Moloo, S. K.
Citation
Publication - International Scientific Council for Trypanosomiasis Research and Control, 1991, No.115, pp 371-372
Abstract

Teneral G. morsitans centralis were fed on the flanks of the African buffalo (Synceros caffer), N'Dama (Bos taurus) or Boran (B. indicus) cattle infected with T. congolense. The infected tsetse were maintained on rabbits and on day 30 after the infected feed, the surviving tsetse were dissected to...

Author(s)
Moloo, S. K.; Olubayo, R. O.; Kabata, J. M.; Okumu, I. O.
Citation
Medical and Veterinary Entomology, 1992, 6, 3, pp 225-230
Abstract

Isometamidium chloride was administered as a single prophylactic dose of 0.5 mg/kg bwt to each of 10 Boran (Bos indicus) steers. At monthly intervals following drug administration, groups of 5 cattle each were challenged with one of 2 different T. vivax populations (stock IL 2982 from Galana, Kenya ...

Author(s)
Peregrine, A. S.; Moloo, S. K.; Whitelaw, D. D.
Citation
Tropical Animal Health and Production, 1991, 23, 1, pp 29-38
Abstract

In experimental infections of N'Dama cattle with T. congolense, it was shown that the animals demonstrated a capacity to control anaemia, which improved following each subsequent challenge (by infected G. m. centralis) and was not related to an improvement in parasite control (with Berenil...

Author(s)
Paling, R. W.; Moloo, S. K.; Scott, J. R.
Citation
Publication - International Scientific Council for Trypanosomiasis Research and Control, 1988, No. 144, pp 256-264

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