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Abstract

An overview of the chemotherapy research programme against trypanosomiasis undertaken at the International Laboratory for Research on Animal Diseases in Kenya, is given. Work carried out is grouped under the following 8 broad topics: development of in vitro culture techniques for identifying and...

Author(s)
Peregrine, A. S.; Sutherland, I. A.; Mutharia, L.; Jamnadass, R.; Gray, M. A.; Codjia, V.; Aliu, Y. O.; Mamman, M.; Silayo, R.; D'Ieteren, G. D. M.; Moloo, S. K.; Murphy, N. B.
Publisher
International Laboratory for Research on Animal Diseases, Nairobi, Kenya
Citation
Chemotherapy for trypanosomiasis. Proceedings of a workshop held at ILRAD, Nairobi, Kenya, 21-24 August, 1989., 1990, pp 3-8
Abstract

The development of improved control strategies for Glossina-transmitted bovine trypanosomiasis is discussed. The use of sterile insect release (SIR) and of attractive insecticide-impregnated targets may replace insecticidal spraying. It is considered that chemotherapy must continue to play a role...

Author(s)
Moloo, S. K.
Publisher
Universiti Pertanian Malaysia, Serdang, Malaysia
Citation
Livestock production and diseases in the Tropics. Proceedings of the 5th International Conference, Kuala Lumpur, Malaysia, 18-22 August 1986., 1986, pp 133-135
Abstract

The exploitation of trypanotolerant cattle and their use in the integrated control of trypanosomiasis is discussed with regard to the possible use of such a system to collect data on the cost-effectiveness, efficacy of control measures and livestock production in areas with East Coast Fever.

Author(s)
Murray, M.; Trail, J. C. M.; D'Ieteren, G.; Paling, R. W.; Leak, S. G. A.; Maehl, J. H. H.; Moloo, S. K.
Publisher
International Laboratory for Research on Animal Diseases, P.O. Box 30709, Nairobi, Kenya
Citation
Immunization against theileriosis in Africa. Proceedings of a Joint Workshop, 1-5 October 1984, Nairobi, Kenya, ILRAD & FAO., 1985, pp 129-132
Abstract

Four Boran cattle were infected with Trypanosoma brucei using Glossina morsitans centralis and were left untreated throughout the experimental period of 18 months. During this period, sequential blood samples were collected and examined for the presence of antitrypanosome antibodies and their...

Author(s)
Masake, R. A.; Moloo, S. K.; Nantulya, V. M.; Minja, S. H.; Makau, J. M.; Njuguna, J. T.
Citation
Veterinary Parasitology, 1995, 56, 1/3, pp 37-46
Abstract

Glossina morsitans centralis infected with metacyclic T. congolense were allowed to feed on cattle which were treated with Berenil 17 days later. 13 days after treatment they were given an homologous challenge (by tsetse fly bite). In the first experiment, 11 N'Dama cattle (3 to 4 years old) were...

Author(s)
Mawuena, K.; Karbe, E.; Fimmen, H. O.; Moloo, S. K.
Publisher
Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), Eschborn, GFR,
Citation
Trypanotolerance and animal production. Proceedings of the Workshop 10-14 May 1982, Lome et Avetonou, Togo. (Schriftenreihe der GTZ No.116)., 1982, pp 168-172
Abstract

Local skin reactions (termed chancres) were elicited in susceptible cattle and goats after challenge with Glossina morsitans morsitans infected with Trypanosoma congolense, T. brucei or T. vivax. The development of the chancre and the detection of parasites within the lesion preceded the appearance ...

Author(s)
Emery, D. L.; Akol, G. W. O.; Murray, M.; Morrison, W. I.; Moloo, S. K.
Publisher
Elsevier/North Holland Biomedical Press., Amsterdam, Netherlands
Citation
The host-invader interplay. Proceedings of the Third International Symposium on the Biochemistry of Parasites and Host-Parasite Relationships, Beerse, Belgium, 30 June-3 July, 1980, 1980, pp 345-356
Abstract

Trypanosome-free eland, waterbuck, East African goats and cattle were exposed to tsetse flies infected with Trypanosoma congolense, T. brucei or T. vivax; buffalo and oryx were similarly exposed to T. congolense. The wild species exhibited more resistance to infection than the domestic controls (...

Author(s)
Grootenhuis, J. G.; Varma, Y.; Black, S.; Moloo, S. K.; Akol, G. W. O.; Emery, D. L.; Murray, M.
Publisher
Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), Eschborn, GFR,
Citation
Trypanotolerance and animal production. Proceedings of the Workshop 10-14 May 1982, Lome et Avetonou, Togo. (Schriftenreihe der GTZ No.116)., 1982, pp 37-42
Abstract

Twelve calves, approximately 10 months of age, of the N'Dama, Zebu and Braunvieh breeds were kept in a fly-proof stable and cyclically infected for the first time with cloned Trypanosoma congolense ILRAD 1323 using G. morsitans centralis at 18 skin sites/animal. All animals became parasitaemic and...

Author(s)
Karbe, E.; Mawuena, K.; Kissling, K.; Moloo, S. K.
Publisher
Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), Eschborn, GFR,
Citation
Trypanotolerance and animal production. Proceedings of the Workshop 10-14 May 1982, Lome et Avetonou, Togo. (Schriftenreihe der GTZ No.116)., 1982, pp 162-167
Abstract

Four African buffalo (Syncerus caffer) and 4 Boran cattle (Bos indicus) were each exposed to the bites of 10 G. morsitans centralis infected with T. congolense (IL 1180). Although both groups of animals became infected, the buffalo showed no clinical signs of trypanosomiasis while the cattle...

Author(s)
Grootenhuis, J. G.; Dwinger, R. H.; Dolan, R. B.; Moloo, S. K.; Murray, M.
Citation
Veterinary Parasitology, 1990, 35, 3, pp 219-231
Abstract

5 cattle were treated intramuscularly with isometamidium chloride at a dose rate of 0.5mg/kg body weight (bw) and challenged 28 days later with 5 Glossina morsitans centralis infected with T. congolense IL 3580 (a clone which exhibits a low level of resistance to isometamidium chloride). All 5 ...

Author(s)
Sutherland, I. A.; Codjia, V.; Moloo, S. K.; Holmes, P. H.; Peregrine, A. S.
Citation
Tropical Animal Health and Production, 1992, 24, 3, pp 157-163

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