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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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The Bla component of the avermectins is an alpha -L-oleandrosyl- alpha -L-oleandroside macrocyclic lactone. When given to sheep as a single oral dose at 0.1 mg/kg it caused a reduction of >95% in the numbers of Haemonchus contortus, Ostertagia circumcincta (including inhibited 4th-stage larvae),...

Egerton, J. R.; Ostlind, D. A.; Blair, L. S.; Eary, C. H.; Suhayda, D.; Cifelli, S.; Riek, R. F.; Campbell, W. C.
Antimicrobial Agents and Chemotherapy, 1979, 15, 3, pp 372-378