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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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Abstract

A series of 28 controlled anthelmintic studies, involving 634 cattle, was conducted throughout North America and Europe to evaluate the efficacy of doramectin against a broad range of gastrointestinal parasitic nematode species and lungworms in naturally and experimentally infected animals. Within...

Author(s)
Jones, R. M.; Logan, N. B.; Weatherley, A. J.; Little, A. S.; Smothers, C. D.
Citation
Veterinary Parasitology, 1993, 49, 1, pp 27-37
Abstract

Doramectin, 25-cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1a, was selected as the best of a series of novel avermectins prepared by mutational biosynthesis. The primary evaluation of its in vivo antiparasitic activity was carried out using a rat Trichostrongylus colubriformis model...

Author(s)
Goudie, A. C.; Evans, N. A.; Gration, K. A. F.; Bishop, B. F.; Gibson, S. P.; Holdom, K. S.; Kaye, B.; Wicks, S. R.; Lewis, D.; Weatherley, A. J.; Bruce, C. I.; Herbert, A.; Seymour, D. J.
Citation
Veterinary Parasitology, 1993, 49, 1, pp 5-15
Abstract

Three studies were conducted involving cattle exposed to experimental nematode infections. These studies were designed to investigate the prophylactic activity of a single s.c. treatment of doramectin at 200 µg/kg bwt against infections of Ostertagia ostertagi, Cooperia oncophora and Dictyocaulus...

Author(s)
Weatherley, A. J.; Hong, C.; Harris, T. J.; Smith, D. G.; Hammet, N. C.
Citation
Veterinary Parasitology, 1993, 49, 1, pp 45-50