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Abstract

Onchocerciasis, a neglected tropical disease prevalent in western and central Africa, is a major health problem and has been targeted for elimination. The causative agent for this disease is the human parasite Onchocerca volvulus. Onchocerca ochengi and Litomosoides sigmodontis, infectious agents...

Author(s)
Wewer, V.; Makepeace, B. L.; Tanya, V. N.; Peisker, H.; Pfarr, K.; Hoerauf, A.; Dörmann, P.
Publisher
Elsevier Ltd, Oxford, UK
Citation
International Journal for Parasitology, 2017, 47, 14, pp 903-912
Abstract

Background: Recent reports of transmission interruption of Onchocerca volvulus, the causing agent of river blindness, in former endemic foci in the Americas, and more recently in West and East Africa, raise the question whether elimination of this debilitating disease is underway after long-term...

Author(s)
Eisenbarth, A.; Achukwi, M. D.; Renz, A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS Neglected Tropical Diseases, 2016, 10, 2, pp e0004392
Abstract

Background: microRNAs (miRNAs), a class of short, non-coding RNA can be found in a highly stable, cell-free form in mammalian body fluids. Specific miRNAs are secreted by parasitic nematodes in exosomes and have been detected in the serum of murine and dog hosts infected with the filarial nematodes ...

Author(s)
Quintana, J. F.; Makepeace, B. L.; Babayan, S. A.; Ivens, A.; Pfarr, K. M.; Blaxter, M.; Debrah, A.; Wanji, S.; Ngangyung, H. F.; Bah, G. S.; Tanya, V. N.; Taylor, D. W.; Hoerauf, A.; Buck, A. H.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2015, 8, 58, pp (27 January 2015)
Abstract

Previous studies have demonstrated that the presence of larvae of other filarial species in Simulium damnosum sensu lato can distort estimates of transmission potential for Onchocerca volvulus in West Africa. However, studies conducted in foci of onchocerciasis in West Central Uganda indicated that ...

Author(s)
Verocai, G. G.; Hassan, H. K.; Lakwo, T.; Habomugisha, P.; Katabarwa, M. N.; Begumisa, S.; Clouds, P.; Katamanywa, J.; Nahabwe, C.; Unnasch, T. R.
Publisher
American Society of Tropical Medicine and Hygiene, Deerfield, USA
Citation
American Journal of Tropical Medicine and Hygiene, 2017, 97, 6, pp 1843-1845
Abstract

Onchocerca ochengi is a nodule-forming filarial nematode parasite of cattle in tropical Africa and closely related to the human pathogen Onchocerca volvulus. The adult worms reside in intradermal nodules. While females are sedentary, males may move between nodules. The first stage larvae...

Author(s)
Hildebrandt, J. C.; Eisenbarth, A.; Renz, A.; Streit, A.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2014, 205, 1/2, pp 318-329
Abstract

Human onchocerciasis (river blindness), caused by the filarial nematode Onchocerca volvulus, has been successfully controlled by a single drug, ivermectin, for over 25 years. Ivermectin prevents the disease symptoms of severe itching and visual impairment by killing the microfilarial stage, but...

Author(s)
Bah, G. S.; Tanya, V. N.; Makepeace, B. L.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2015, 212, 1/2, pp 25-34
Abstract

Onchocerca ochengi, a filarial nematode parasite from African Zebu cattle is considered to be the closest relative of Onchocerca volvulus, the causative agent of river blindness. Both Onchocerca species share the vector, black flies of the Simulium damnosum complex. Correct identification of their...

Author(s)
Eisenbarth, A.; Ekale, D.; Hildebrandt, J.; Achukwi, M. D.; Streit, A.; Renz, A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Acta Tropica, 2013, 127, 3, pp 261-265
Abstract

Onchocerciasis (river blindness), caused by the filarial nematode Onchocerca volvulus, is a major cause of visual impairment and dermatitis in sub-Saharan Africa. As O. volvulus contains an obligatory bacterial symbiont (Wolbachia), it is susceptible to antibiotic chemotherapy, although current...

Author(s)
Bah, G. S.; Ward, E. L.; Srivastava, A.; Trees, A. J.; Tanya, V. N.; Makepeace, B. L.
Publisher
American Society for Microbiology (ASM), Washington, USA
Citation
Antimicrobial Agents and Chemotherapy, 2014, 58, 2, pp 801-810
Abstract

Haemoparasites of animals reduce livestock productivity and could lead to high mortality. This study aims at determining the prevalence of haemoparasites as well as the effect of the parasites on blood parameters in ruminants and pigs slaughtered at Bodija abattoir, Ibadan. A total of three hundred ...

Author(s)
Ademola, I. O.
Publisher
University of Ibadan, Ibadan, Nigeria
Citation
African Journal of Biomedical Research, 2013, 16, 2, pp 101-105
Abstract

Human onchocerciasis, also known as River Blindness, is a debilitating disease caused by the filarial nematode Onchocerca volvulus. Many, but not all, filarial nematodes carry within their tissues endosymbiotic, Rickettsia-like bacteria of the genus Wolbachia. Onchocerca spp. infections in cattle...

Author(s)
Neary, J. M.; Trees, A. J.; Ekale, D. D.; Tanya, V. N.; Hetzel, U.; Makepeace, B. L.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Parasitology, 2010, 174, 3/4, pp 267-276

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