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Veterinary information to support practice, based on evidence and continuing education

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Using alternating passage between HeLa and bovine embryo kidney cultures, infectious bovine rhinotracheitis virus was adapted to HeLa cells and propagated through 26 serial transfers. The adapted virus rapidly destroyed HeLa cells and yielded, when measured in bovine kidney cell cultures, virus...

Cabasso, V. J.; Brown, R. G.; Cox, H. R.
Proceedings of the Society for Experimental Biology and Medicine, 1957, 95, pp 471-476

The defects of existing killed vaccines, namely short duration of immunity necessitating annual revaccination, post vaccinal paralytic accidents and high cost are discussed. Work done with the chick-embryo adapted Flury strain of the virus is then described. This strain was originally isolated from ...

Cox, H. R.
Proc. 53rd Meet. U.S. Live Stk. sanit. Ass., 1949, pp 8-16 pp.