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Abstract

Although the post-mortem diagnosis of bovine tuberculosis is mainly achieved through microbiological culture, the development of other techniques to detect Mycobacterium tuberculosis complex (MTBC) members directly from tissue samples has been pursued. The present study describes the development,...

Author(s)
Lorente-Leal, V.; Liandris, E.; Castellanos, E.; Bezos, J.; Domínguez, L.; Juan, L. de; Romero, B.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2019, 6, March, pp 61
Abstract

We evaluated the sensitivity (Se) of the single cervical intradermal tuberculin (SIT) test, two interferon-gamma (IFN-γ) assays and three different antibody detection techniques for bovine tuberculosis (bTB) diagnosis in 131 mixed beef breed cattle. The results of the diagnostic techniques...

Author(s)
Casal, C.; Infantes, J. A.; Risalde, M. A.; Díez-Guerrier, A.; Domínguez, M.; Moreno, I.; Romero, B.; Juan, L. de; Sáez, J. L.; Juste, R.; Gortázar, C.; Domínguez, L.; Bezos, J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2017, 112, pp 214-221
Abstract

Background: Serum antibody detection has potential as a complementary diagnostic tool in animal tuberculosis (TB) control, particularly in multi-host systems. The objective of the present study was to assess the specificity (Sp) of an enzyme-linked immunosorbent assay (ELISA) based on the new...

Author(s)
Infantes-Lorenzo, J. A.; Moreno, I.; Roy, A.; Risalde, M. A.; Balseiro, A.; Juan, L. de; Romero, B.; Bezos, J.; Puentes, E.; Ǻkerstedt, J.; Tessema, G. T.; Gortázar, C.; Domínguez, L.; Domínguez, M.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2019, 15, 70, pp (1 March 2019)
Abstract

The Eurasian wild boar (Sus scrofa) is the main wild reservoir of the Mycobacterium tuberculosis complex in Mediterranean woodlands and a key risk factor for cattle tuberculosis (TB) breakdowns. Wild boar vaccination therefore has the potential to be a valuable tool for TB control. We tested two...

Author(s)
Díez-Delgado, I.; Sevilla, I. A.; Romero, B.; Tanner, E.; Barasona, J. A.; White, A. R.; Lurz, P. W. W.; Boots, M.; Fuente, J. de la; Dominguez, L.; Vicente, J.; Garrido, J. M.; Juste, R. A.; Aranaz, A.; Gortazar, C.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Preventive Veterinary Medicine, 2018, 155, pp 11-20
Abstract

The official technique for diagnosis of bovine tuberculosis (bTB) worldwide is the tuberculin skin test, based on the evaluation of the skin thickness increase after the intradermal inoculation of a purified protein derivative (PPD) in cattle. A number of studies performed on experimentally...

Author(s)
Casal, C.; Alvarez, J.; Bezos, J.; Quick, H.; Díez-Guerrier, A.; Romero, B.; Saez, J. L.; Liandris, E.; Navarro, A.; Perez, A.; Domínguez, L.; Juan, L. de
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Preventive Veterinary Medicine, 2015, 121, 1/2, pp 86-92
Abstract

Vaccination against tuberculosis (TB) is prohibited in cattle or other species subjected to specific TB eradication campaigns, due to the interference that it may cause with the official diagnostic tests. However, immunization with a heat-inactivated (HI) Mycobacterium bovis vaccine via the oral...

Author(s)
Roy, A.; Risalde, M. A.; Casal, C.; Romero, B.; Juan, L. de; Menshawy, A. M.; Díez-Guerrier, A.; Juste, R. A.; Garrido, J. M.; Sevilla, I. A.; Gortázar, C.; Domínguez, L.; Bezos, J.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2017, 4, August, pp 124
Abstract

Despite great effort and investment incurred over decades to control bovine tuberculosis (bTB), it is still one of the most important zoonotic diseases in many areas of the world. Test-and-slaughter strategies, the basis of most bTB eradication programs carried out worldwide, have demonstrated its...

Author(s)
Álvarez, J.; Perez, A.; Marqués, S.; Bezos, J.; Grau, A.; Cruz, M. L. de la; Romero, B.; Saez, J. L.; Esquivel, M. del R.; Martínez, M. del C.; Mínguez, O.; Juan, L. de; Domínguez, L.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2014, 10, 14, pp (13 January 2014)
Abstract

Goats can act as reservoirs for tuberculosis (TB) infection. The main etiological agents of TB in goats are Mycobacterium caprae and Mycobacterium bovis and they infect also a wide range of domestic and wild animals and humans. Control programmes based mainly on the application of single and...

Author(s)
Bezos, J.; Marqués, S.; Álvarez, J.; Casal, C.; Romero, B.; Grau, A.; Mínguez, O.; Domínguez, L.; Juan, L. de
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2014, 96, 1, pp 39-46
Abstract

Mycobacterium bovis is the main causative agent of bovine tuberculosis. This zoonotic disease produces important economic losses and must be considered a threat to endangered animal species and public health. This study was performed (1) to assess the degree of diversity of the Spanish M. bovis...

Author(s)
Rodríguez, S.; Romero, B.; Bezos, J.; Juan, L. de; Álvarez, J.; Castellanos, E.; Moya, N.; Lozano, F.; González, S.; Sáez-Llorente, J. L.; Mateos, A.; Domínguez, L.; Aranaz, A.
Publisher
Elsevier Inc., New York, USA
Citation
Veterinary Microbiology, 2010, 141, 1/2, pp 89-95
Abstract

South American camelids are susceptible to tuberculosis, caused mainly by Mycobacterium bovis and M. microti. Despite the tuberculin skin test being the official test for tuberculosis, it has a very low sensitivity in these species (14-20%). Serological tests present the advantages of being rapid,...

Author(s)
Infantes-Lorenzo, J. A.; Whitehead, C. E.; Moreno, I.; Bezos, J.; Roy, A.; Domínguez, L.; Domínguez, M.; Salguero, F. J.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, August, pp 189

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