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Abstract

Nutrigenomics in dairy cows is a relatively new area of research. It is defined as the study of the genomewide influences of nutrition altering the expression of genes. Dietary compounds affect gene expression directly or indirectly via interactions with transcription factors. Among those, the most ...

Author(s)
Bionaz, M.; Osorio, J.; Loor, J. J.
Publisher
American Society of Animal Science, Savoy, USA
Citation
Journal of Animal Science, 2015, 93, 12, pp 5531-5553
Abstract

Recent studies demonstrating a higher incidence of metabolic disorders after calving have challenged the management practice of increasing dietary energy density during the last ∼3 wk prepartum. Despite our knowledge at the whole-animal level, the tissue-level mechanisms that are altered in...

Author(s)
Vailati-Riboni, M.; Kanwal, M.; Bulgari, O.; Meier, S.; Priest, N. V.; Burke, C. R.; Kay, J. K.; McDougall, S.; Mitchell, M. D.; Walker, C. G.; Crookenden, M.; Heiser, A.; Roche, J. R.; Loor, J. J.
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Journal of Dairy Science, 2016, 99, 1, pp 758-770
Abstract

Peripartum, and especially during the transition period, dairy cows undergo dramatic physiological changes. These coincide with an increased risk of disease during the first 2 wk after calving and have been linked to dairy cows failing to achieve production as well as reproductive targets. Previous ...

Author(s)
Heiser, A.; McCarthy, A.; Wedlock, N.; Meier, S.; Kay, J.; Walker, C.; Crookenden, M. A.; Mitchell, M. D.; Morgan, S.; Watkins, K.; Loor, J. J.; Roche, J. R.
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Journal of Dairy Science, 2015, 98, 2, pp 937-946
Abstract

Objectives were to (1) determine the feasibility of performing hoof biopsies without impairing locomotion; (2) evaluate the feasibility of using biopsied tissue for quantitative PCR; and (3) compare relative gene expression among claws for several target genes. Biopsies were performed on 6 Holstein ...

Author(s)
Osorio, J. S.; Fraser, B. C.; Graugnard, D. E.; Singh, S. S.; Drackley, J. K.; Garrett, E. F.; Loor, J. J.
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Journal of Dairy Science, 2012, 95, 11, pp 6388-6396
Abstract

Dietary lipid supplements affect mammary lipid metabolism partly through changes in lipogenic gene expression. Quantitative PCR (qPCR) is a sensitive, reliable, and accurate technique for gene expression analysis. However, variation introduced in qPCR data by analytical or technical errors needs to ...

Author(s)
Kadegowda, A. K. G.; Bionaz, M.; Thering, B.; Piperova, L. S.; Erdman, R. A.; Loor, J. J.
Publisher
American Dairy Science Association, Savoy, USA
Citation
Journal of Dairy Science, 2009, 92, 5, pp 2007-2019

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