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VetMed Resource

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Abstract

The tests for trypanocidal drug resistance currently in use or in development are briefly reviewed under the headings: in vivo assays for resistance in cattle and mice; in vitro drug assays; drug incubation infectivity tests; measurement of circulating levels of trypanocidal compounds in treated ...

Author(s)
Sutherland, I. A.; Holmes, P. H.
Publisher
Merck & Co. Inc., Rahway, NJ, USA
Citation
Resistance of parasites to antiparasitic drugs: Round Table Conference, ICOPA VII Paris 1990., 1990, pp 25-31
Abstract

An ELISA was developed to measure accurately levels of the trypanocidal drug isometamidium in the serum of treated cattle. The assay requires only 5 µl of test serum, is sensitive to a level of 0.5 pg/ml and is highly specific. Cross reactivity does not occur with the two other widely used...

Author(s)
Whitelaw, D. D.; Gault, E. A.; Holmes, P. H.; Sutherland, I. A.; Rowell, F. J.; Phillips, A.; Urquhart, G. M.
Citation
Research in Veterinary Science, 1991, 50, 2, pp 185-189
Abstract

Author(s)
Whitelaw, D. D.; Gault, E. A.; Sutherland, I. A.; Holmes, P. H.; Rowell, F. J.; Phillips, A.; Urquhart, G. M.
Citation
Publication - International Scientific Council for Trypanosomiasis Research and Control, 1991, No.115, pp 341-346