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Abstract

Serum from 87 cattle was tested before and 14 days after vaccination against F & M virus type O2 in the plaque method of the neutralization test. The neutralization titres were compared with the results of direct challenge of immunity performed 14 days after vaccination. In most of the 87 cattle, a ...

Author(s)
Rüting, E.; Seils, R.; Weyhe, D.; Benndorf, E.
Publisher
Loefflcr Inst., X-2201 Insel Riems, E. Germany,
Citation
Archiv fur Experimentelle Veterinarmedizin, 1969, 23, pp 827-838
Abstract

Bovine potency, 50% protective dose and protection percentages of three trivalent F & M vaccines have been compared with neutralizing and precipitating antibody titres induced in vaccinated cattle and in rabbits. The results of the in vivo and in vitro potency tests were compared to the amounts of...

Author(s)
Leunen, J.; Strobbe, R.; Debecq, J.
Citation
Ann. Med. vet., 1971, 115, pp 209-244
Abstract

In studies on survival of F & M disease virus in various tissues of infected animals and in route-dose experiments, 301 cattle were inoculated to detect virus. Of these, 138 became infected and had clinical signs and lesions while 163 were clinically refractory. To determine if the refractory ...

Author(s)
Cottral, G. E.; Gailiunas, P.; Seibold, H. R.; Campion, R.
Publisher
Plum Island Anim. Dis. Lab. Greenport, Long Island, N.Y.,
Citation
Proceedings. United States Live Stock Sanitary Association, 1964, 1965, pp 360-374 pp.
Abstract

The strength of the immunity in sheep vaccinated with inactivated trivalent vaccine can be measured either by the titration of neutralizing antibodies in cell culture or by the resistance to challenge inoculation. Virus titrations can be carried out in vaccinated sheep by multiple tongue...

Author(s)
FéDida, M.; Dannacher, G.; Thomas, J. P.; Peillon, M.; Coudert, M.
Publisher
Office International des Epizooties, Paris, France
Citation
Bulletin de l'Office International des Epizooties, 1970, 73, pp 653-686
Abstract

Innocuity can be controlled in cultures of calf kidney cells after neutralization with formalin and elution of the virus. The neutralization of formalin by bisulphite does not adversely affect the virus, and the elution technique allows the recovery of minute quantities of virus added to a vaccine. ...

Author(s)
Dannacher, G.; Fedida, M.; Thomas, J. -P.; Coudert, M.; Peilion, M.
Citation
Recueil de Medecine Veterinaire, 1970, 146, pp 1395-1414
Abstract

A method of attenuating FMD virus without loss of immunogenicity consisted of subjecting type A22 virus (strain No. 663) to 84 serial passages in primary bovine kidney tissue cultures incubated at 24 °C. A vaccine prepared from the strain further attenuated by a further 6-10 passages in primary...

Author(s)
Urvantsev, N. M.; Syusyukin, A. A.; Sergeev, V. A.; Prokhorov, V. V.
Publisher
Moscow,
Citation
Veterinariya, 1971, 1, pp 37-39 pp.
Abstract

The authors prepared eight trivalent (O, A, and C) vaccines, corresponding to incubation times of 6, 12, 18, 24, 36, 48, 72 and 120 hours. The properties of the virus have been established for these different times and the vaccines prepared with them have been checked on 216 cattle from Ireland....

Author(s)
Mammerickx, M.; Leunen, J.
Publisher
Uccle, Brussels: Institut National de Recherches Vétérinaires [F.e.fl.,
Citation
Prolonged culture of foot and mouth disease virus types O, A and C in bovine foetal kidney cells in rolling flasks., 1966, pp 93 pp.
Abstract

The test was performed by a micro-method, using g.pig hyperimmune serum and virus antigen of high titre produced in tissue culture Two hours at room temp. or one hour at 37°C gave the best results. The test was suitable for measuring the antibody response to a vaccine.-RM.

Author(s)
Roumiantzeff, M.; Salvatori, J.; CaillèRe, F.
Citation
Recueil de Medecine Veterinaire, 1969, 145, pp 455-463
Abstract

A detailed account of the method of preparation of F & M disease vaccine in the Netherlands is given. The method is based on that of Frenkel, and vaccine is prepared against A, O and C types of the virus. Sufficient vaccine is prepared to enable the whole cattle population of over 4 million animals ...

Author(s)
van Bekkum, J. G.
Citation
Tijdschrift voor Diergeneeskunde, 1969, 94, pp 758-767
Abstract

Two experimental batches of killed vaccine were prepared from each of five strains of type O virus (Ardennes, Bruges, Espagne, Lausanne, Vienne) cultured in expiants of bovine lingual epithelium. The complement fixation titre of the live untreated vaccine virus after fluorocarbon treatment proved...

Author(s)
Strobbe, R.; Debecq, J.; Leunen, J.
Publisher
Office International des Epizooties, Paris, France
Citation
Bulletin de l'Office International des Epizooties, 1969, 71, pp 397-404

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