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Abstract

A method of attenuating FMD virus without loss of immunogenicity consisted of subjecting type A22 virus (strain No. 663) to 84 serial passages in primary bovine kidney tissue cultures incubated at 24 °C. A vaccine prepared from the strain further attenuated by a further 6-10 passages in primary...

Author(s)
Urvantsev, N. M.; Syusyukin, A. A.; Sergeev, V. A.; Prokhorov, V. V.
Publisher
Moscow,
Citation
Veterinariya, 1971, 1, pp 37-39 pp.
Abstract

Two experimental batches of killed vaccine were prepared from each of five strains of type O virus (Ardennes, Bruges, Espagne, Lausanne, Vienne) cultured in expiants of bovine lingual epithelium. The complement fixation titre of the live untreated vaccine virus after fluorocarbon treatment proved...

Author(s)
Strobbe, R.; Debecq, J.; Leunen, J.
Publisher
Office International des Epizooties, Paris, France
Citation
Bulletin de l'Office International des Epizooties, 1969, 71, pp 397-404
Abstract

Ten strains modified for cattle were tested in pigs by injection into muscle, tongue and snout, coronary band, and bulb of the heel. Eight strains produced clinical lesions in a proportion of pigs, and seven of these were transmissible to in-contact controls, in which the ratio of subclinical to...

Author(s)
Burrows, R.
Publisher
Office International des Epizooties, Paris, France
Citation
Bulletin de l'Office International des Epizooties, 1964, 61, pp 1251-1275
Abstract

The method, for monovalent vaccines, consists in: vaccinating cattle with varying doses; administering challenge dose-criterion of protection being absence of secondary foot lesions up to 5 days after challenge; and estimation of the D50, by Litchfield's method. Thus, the efficacy of a vaccine can...

Author(s)
Terré, J.; Bornarel, P.; Stellmann, C.; Soulebot, J.
Citation
Recueil de Medecine Veterinaire, 1965, 141, pp 1109-1130
Abstract

This method eliminates the permanent focus of infection created by infected cattle; it is of value for studies of the different factors of virus multiplication; it requires relatively simple equipment and enables large-scale production of vaccine in case of epidemics caused by new strains of the...

Author(s)
Dubouclard, C.; Roumiantzeff, M.; Fontaine, J.; Mackowiak, C.
Publisher
Societe des Sciences Veterinaires de Lyon, Lyon, France
Citation
Bulletin de la Societe des Sciences Veterinaires de Lyon, 1966, 68, pp 243-253
Abstract

A type O and a type C virus strain were used to compare the results of titration in live cattle using Henderson's method of i/d tongue inj. [see V.B. 20, abst. 350] and of titration in pig kidney tissue cultures. Higher titres were obtained with the tissue culture method; with the type O virus the...

Author(s)
Kobusiewicz, T.; Wisniewski, J.
Citation
Medycyna weterynaryjna, 1965, 21, pp 16-18
Abstract

Type O virus grew better in day-old chicks than in embryonated eggs. After 101 to 103 passages it caused mild post-vaccinal lesions in some cattle. There was good immunity in 70% after 2-4 weeks. In the field incidence of lesions was lower (0.05%). Preparation of the vaccine is described; storage...

Author(s)
Palacios Garcia, C.
Publisher
Office International des Epizooties, Paris, France
Citation
Bulletin de l'Office International des Epizooties, 1964, 61, pp 757-800
Abstract

Various techniques are discussed and a plan is proposed for centralization, unification and standardization of the process. The basis would be testing of cattle; difficulties are discussed and recommendations made for the provision and allocation of the estimated requirement of 4, 000-5, 000...

Author(s)
Rivenson, S.
Citation
Revista de Investigaciones Ganaderas, 1962, 13, pp 3-45 pp.
Abstract

SWINE FEVER: a trial of the Chinese strain of lapinized virus showed that it was safe to use as a vaccine in Belgium. Antibodies to porcine picorna-virus (SMEDI virus) were found in at least 59 of 194 serum samples; their incidence did not seem to be related to abortion and sterility. A comparison...

Publisher
INRV, 99 Groeselenberg, 1180 Bruxelles,
Citation
Institut National de Recherches Veterinaires, Uccle. Rapport d'activite 1969., 1970, pp 125 pp.
Abstract

Of 26 strains isolated directly from the tongue of infected cattle, 7 were not cytopathic for calf kidney cells, and 19 were cytopathic in different degrees. A strain undergoing passages in tongue epithelium according to Frenkel's method was initially non-pathogenic for calf kidney cells, but after ...

Author(s)
Bindrich, H.; Kuwert, E.
Citation
Archiv fur Experimentelle Veterinarmedizin, 1960, 14, pp 142-150

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