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Abstract

Serum from 87 cattle was tested before and 14 days after vaccination against F & M virus type O2 in the plaque method of the neutralization test. The neutralization titres were compared with the results of direct challenge of immunity performed 14 days after vaccination. In most of the 87 cattle, a ...

Author(s)
Rüting, E.; Seils, R.; Weyhe, D.; Benndorf, E.
Publisher
Loefflcr Inst., X-2201 Insel Riems, E. Germany,
Citation
Archiv fur Experimentelle Veterinarmedizin, 1969, 23, pp 827-838
Abstract

Bovine potency, 50% protective dose and protection percentages of three trivalent F & M vaccines have been compared with neutralizing and precipitating antibody titres induced in vaccinated cattle and in rabbits. The results of the in vivo and in vitro potency tests were compared to the amounts of...

Author(s)
Leunen, J.; Strobbe, R.; Debecq, J.
Citation
Ann. Med. vet., 1971, 115, pp 209-244
Abstract

The strength of the immunity in sheep vaccinated with inactivated trivalent vaccine can be measured either by the titration of neutralizing antibodies in cell culture or by the resistance to challenge inoculation. Virus titrations can be carried out in vaccinated sheep by multiple tongue...

Author(s)
FéDida, M.; Dannacher, G.; Thomas, J. P.; Peillon, M.; Coudert, M.
Publisher
Office International des Epizooties, Paris, France
Citation
Bulletin de l'Office International des Epizooties, 1970, 73, pp 653-686
Abstract

A method of attenuating FMD virus without loss of immunogenicity consisted of subjecting type A22 virus (strain No. 663) to 84 serial passages in primary bovine kidney tissue cultures incubated at 24 °C. A vaccine prepared from the strain further attenuated by a further 6-10 passages in primary...

Author(s)
Urvantsev, N. M.; Syusyukin, A. A.; Sergeev, V. A.; Prokhorov, V. V.
Publisher
Moscow,
Citation
Veterinariya, 1971, 1, pp 37-39 pp.
Abstract

The test was performed by a micro-method, using g.pig hyperimmune serum and virus antigen of high titre produced in tissue culture Two hours at room temp. or one hour at 37°C gave the best results. The test was suitable for measuring the antibody response to a vaccine.-RM.

Author(s)
Roumiantzeff, M.; Salvatori, J.; CaillèRe, F.
Citation
Recueil de Medecine Veterinaire, 1969, 145, pp 455-463
Abstract

A detailed account of the method of preparation of F & M disease vaccine in the Netherlands is given. The method is based on that of Frenkel, and vaccine is prepared against A, O and C types of the virus. Sufficient vaccine is prepared to enable the whole cattle population of over 4 million animals ...

Author(s)
van Bekkum, J. G.
Citation
Tijdschrift voor Diergeneeskunde, 1969, 94, pp 758-767
Abstract

Two experimental batches of killed vaccine were prepared from each of five strains of type O virus (Ardennes, Bruges, Espagne, Lausanne, Vienne) cultured in expiants of bovine lingual epithelium. The complement fixation titre of the live untreated vaccine virus after fluorocarbon treatment proved...

Author(s)
Strobbe, R.; Debecq, J.; Leunen, J.
Publisher
Office International des Epizooties, Paris, France
Citation
Bulletin de l'Office International des Epizooties, 1969, 71, pp 397-404
Abstract

It is concluded that g.-pigs are suitable for assay provided they weigh about 500 g. each, are in good health, come from known breeding establishments and are kept under constant conditions of husbandry during experiments. A good immune response was elicited by i/m injection; antibody titres...

Author(s)
Roumiantzeff, M.; Fontaine, J.; Stellman, C.; Mackowiak, C.
Publisher
Institut de la Fièvre Aphteuse, Lyon.,
Citation
Revue de Medicine Veterinaire, 1965, 116, pp 597-607
Abstract

It is concluded that g.-pigs are suitable for assay provided they weigh about 500 g. each, are in good health, come from known breeding establishments and are kept under constant conditions of husbandry during experiments. A good immune response was elicited by i/m injection; antibody titres...

Author(s)
Stellmann, C.; Terre, J.; Roumiantzeff, M.; Bornarel, P.
Publisher
Institut de la Fièvre Aphteuse, Lyon.,
Citation
Revue de Medicine Veterinaire, 1965, 116, pp 609-615
Abstract

A method for assessing the cross-vaccinating dose 50 (CVD50) in g.pigs is described. By this technique it is possible to differentiate variants, which it is not possible to do in a statistically significant manner by the qualitative test in cattle. It is possible to express, by coefficients, the...

Author(s)
Fontaine, J.; Terre, J.; Roumiantzeff, M.; Dubouclard, C.; Bornarel, P.; Favre, H.
Publisher
Societe des Sciences Veterinaires de Lyon, Lyon, France
Citation
Bulletin de la Societe des Sciences Veterinaires de Lyon, 1966, 68, pp 161-172

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