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Abstract

For 19 F & M disease viruses (16 cattle strains representing all seven types) the approximate minimum infective dose (MID) expressed in bovine ID50 units, varied: from 0.01 to 2.0 units for tongue route of inoculation in cattle: from 0.01 to 6.0 units for i/p inoculation in mice; and from 0.002 to...

Author(s)
Cottral, G. E.; Patty, R. E.; Gailiunas, P.; Scott, F. W.
Publisher
Office International des Epizooties, Paris, France
Citation
Bulletin de l'Office International des Epizooties, 1965, 63, pp 1607-1625
Abstract

It is concluded that g.-pigs are suitable for assay provided they weigh about 500 g. each, are in good health, come from known breeding establishments and are kept under constant conditions of husbandry during experiments. A good immune response was elicited by i/m injection; antibody titres...

Author(s)
Roumiantzeff, M.; Fontaine, J.; Stellman, C.; Mackowiak, C.
Publisher
Institut de la Fièvre Aphteuse, Lyon.,
Citation
Revue de Medicine Veterinaire, 1965, 116, pp 597-607
Abstract

A method for assessing the cross-vaccinating dose 50 (CVD50) in g.pigs is described. By this technique it is possible to differentiate variants, which it is not possible to do in a statistically significant manner by the qualitative test in cattle. It is possible to express, by coefficients, the...

Author(s)
Fontaine, J.; Terre, J.; Roumiantzeff, M.; Dubouclard, C.; Bornarel, P.; Favre, H.
Publisher
Societe des Sciences Veterinaires de Lyon, Lyon, France
Citation
Bulletin de la Societe des Sciences Veterinaires de Lyon, 1966, 68, pp 161-172
Abstract

Foot-and-mouth disease virus (FMDV) gives two precipitin bands with agar gel diffusion techniques. One band is attributed to 23 mµ infectious particles, the other to 7 mµ, protein subunits. A third antigenic material produced upon infection with FMDV is described here. Infectious baby hamster...

Author(s)
Cowan, K. M.; Graves, J. H.
Citation
Federation Proceedings. Federation of American Societies for Experimental Biology, 1966, 25, pp 615
Abstract

The same techniques were used for the selection of cold mutants as those described for neuroîropic viruses. Type A, O and C were subcultured at 25° C. on calf kidney cells. From the three subcultures clonal selections were made by the plaque method. The viruses obtained did not cause vesicle...

Author(s)
Prunet, P.
Citation
Ann. Inst. Pasteur, 1964, 106, pp 18-28
Abstract

A detailed account is given of: attenuation of the F. & M. disease virus (by passage in white mice, and in 14-day chick embryos); tests for attenuation (in cattle, guineapigs and adult mice); cattle innocuity tests and small animal experiments; storage of attenuated strains and preparation of...

Author(s)
Skinner, H. H.
Publisher
Office International des Epizooties, Paris, France
Citation
Bulletin de l'Office International des Epizooties, 1960, 53, pp 634-650
Abstract

SWINE FEVER: a trial of the Chinese strain of lapinized virus showed that it was safe to use as a vaccine in Belgium. Antibodies to porcine picorna-virus (SMEDI virus) were found in at least 59 of 194 serum samples; their incidence did not seem to be related to abortion and sterility. A comparison...

Publisher
INRV, 99 Groeselenberg, 1180 Bruxelles,
Citation
Institut National de Recherches Veterinaires, Uccle. Rapport d'activite 1969., 1970, pp 125 pp.
Abstract

Type A4 virus was passaged 450 times in kidney cultures of the pig, calf and mouse.
This greatly changed its virulence for ox, pig and infant mouse (the guineapig was not investigated), its cytopathic action on heterologous cultures, its contagiousness for ox and pig, and its immunizing properties. ...

Author(s)
Mayr, A.; Wittmann, G.
Citation
Zentralblatt fur Veterinarmedizin, 1960, 7, pp 829-840
Abstract

It is concluded that g.-pigs are suitable for assay provided they weigh about 500 g. each, are in good health, come from known breeding establishments and are kept under constant conditions of husbandry during experiments. A good immune response was elicited by i/m injection; antibody titres...

Author(s)
Mackowiak, C.; Lang, R.; Petermann, H. G.; Roumiantzeff, M.; Fontaine, J.; Stellman, C.
Publisher
Institut de la Fièvre Aphteuse, Lyon.,
Citation
Revue de Medicine Veterinaire, 1965, 116, pp 497-507
Abstract

A third antigen was produced in tissue cultures of baby hamster kidney (BHK) cells and tissues of g.pigs and cattle infected with type A virus. This antigen is distinct from the recognized 140 S and 12 S antigenic components of the virus. It does not appear to be a virus constituent but is produced ...

Author(s)
Cowan, K. M.; Graves, J. H.
Citation
Virology, 1966, 30, pp 528-540

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