Cookies on VetMed Resource

Like most websites we use cookies. This is to ensure that we give you the best experience possible.

 

Continuing to use www.cabi.org  means you agree to our use of cookies. If you would like to, you can learn more about the cookies we use.

VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

Sign up to receive our Veterinary & Animal Sciences e-newsletter, book alerts and offers direct to your inbox.

Results per page:

Search results

Abstract

An infection and treatment protocol involving infection with a mixture of three parasite isolates and simultaneous treatment with oxytetracycline is currently used to vaccinate cattle against Theileria parva. While vaccination results in high levels of protection in some regions, little or no...

Author(s)
Hemmink, J. D.; Sitt, T.; Pelle, R.; Klerk-Lorist, L. M. de; Shiels, B.; Toye, P. G.; Morrison, W. I.; Weir, W.
Publisher
Elsevier Ltd, Oxford, UK
Citation
International Journal for Parasitology, 2018, 48, 3/4, pp 287-296
Abstract

Immunity against Theileria parva is associated with CD8 T-cell responses that exhibit immunodominance, focusing the response against limited numbers of epitopes. As candidates for inclusion in vaccines, characterization of responses against immunodominant epitopes is a key component in novel...

Author(s)
Connelley, T. K.; Li XiaoYing; MacHugh, N.; Colau, D.; Graham, S. P.; Bruggen, P. van der; Taracha, E. L.; Gill, A.; Morrison, W. I.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Immunology, 2016, 149, 2, pp 172-185
Abstract

Theileria parva is a tick-transmitted, apicomplexan protozoan found in buffalo (Syncerus caffer) and cattle in eastern, central and southern Africa. The parasite causes a fatal, lymphoproliferative disease in susceptible cattle. Previous studies have shown that the parasites in buffalo comprise a...

Author(s)
Sitt, T.; Henson, S.; Morrison, W. I.; Toye, P.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2019, 269, pp 21-27
Abstract

An infection and treatment protocol is used to vaccinate cattle against Theileria parva infection. Due to incomplete cross-protection between different parasite isolates, a mixture of three isolates, termed the Muguga cocktail, is used for vaccination. While vaccination of cattle in some regions...

Author(s)
Hemmink, J. D.; Weir, W.; MacHugh, N. D.; Graham, S. P.; Ekta Patel; Paxton, E.; Shiels, B.; Toye, P. G.; Morrison, W. I.; Pelle, R.
Publisher
Elsevier Ltd, Oxford, UK
Citation
International Journal for Parasitology, 2016, 46, 8, pp 495-506
Abstract

The extent of sequence diversity among the genes encoding 10 antigens (Tp1-10) known to be recognized by CD8+ T lymphocytes from cattle immune to Theileria parva was analysed. The sequences were derived from parasites in 23 buffalo-derived cell lines, three cattle-derived isolates and one cloned...

Author(s)
Sitt, T.; Pelle, R.; Chepkwony, M.; Morrison, W. I.; Toye, P.
Publisher
Cambridge University Press, Cambridge, UK
Citation
Parasitology, 2018, 145, 11, pp 1430-1439
Abstract

The Theileria genus includes a large number of species of tick-borne parasites that infect domestic animals and wildlife species, predominantly ruminants. These range from species, such as T. parva and T. annulata, which cause acute lymphoproliferative diseases in cattle resulting in high levels of ...

Author(s)
Morrison, W. I.
Publisher
Office International des Épizooties, Paris, France
Citation
Revue Scientifique et Technique - Office International des Épizooties, 2015, 34, 2, pp 599-611
Abstract

Infection with Theileria parva is asymptomatic in African buffalo but results in severe disease in cattle. Currently, vaccination relies on infection and treatment, using a mixture of three parasite isolates to overcome the strain specificity of immunity. Genotypic analyses of field populations of ...

Author(s)
Morrison, W. I.; Connelley, T.; Hemmink, J. D.; MacHugh, N. D.
Publisher
Annual Reviews, Palo Alto, USA
Citation
Annual Review of Animal Biosciences, 2015, 3, pp 397-418
Abstract

Respiratory failure and death in East Coast Fever (ECF), a clinical syndrome of African cattle caused by the apicomplexan parasite Theileria parva, has historically been attributed to pulmonary infiltration by infected lymphocytes. However, immunohistochemical staining of tissue from T. parva...

Author(s)
Fry, L. M.; Schneider, D. A.; Frevert, C. W.; Nelson, D. D.; Morrison, W. I.; Knowles, D. P.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2016, 11, 5, pp e0156004
Abstract

Integrative management of wildlife and livestock requires a clear understanding of the diseases transmitted between the two populations. The tick-borne protozoan parasite Theileria parva causes two distinct diseases in cattle, East Coast fever and Corridor disease, following infection with...

Author(s)
Sitt, T.; Poole, E. J.; Ndambuki, G.; Mwaura, S.; Njoroge, T.; Omondi, G. P.; Mutinda, M.; Mathenge, J.; Prettejohn, G.; Morrison, W. I.; Toye, P.
Publisher
Elsevier Ltd, Amsterdam, Netherlands
Citation
International Journal for Parasitology: Parasites and Wildlife, 2015, 4, 2, pp 244-251
Abstract

The NKp46 receptor demonstrates a high degree of lineage specificity, being expressed almost exclusively in NK cells. Previous studies have demonstrated NKp46 expression by T cells, but NKp46+CD3+ cells are rare and almost universally associated with NKp46 acquisition by T cells following...

Author(s)
Connelley, T. K.; Longhi, C.; Burrells, A.; Degnan, K.; Hope, J.; Allan, A. J.; Hammond, J. A.; Storset, A. K.; Morrison, W. I.
Publisher
American Association of Immunologists, Bethesda, USA
Citation
Journal of Immunology, 2014, 192, 8, pp 3868-3880

Refine Results

Sort Order
Author
Geographical Location
Item Type
Organisms
Subject Topics