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Abstract

The duration of a single isometamidium chloride (Samorin) prophylactic treatment against T. congolense ILNat 3.1 and T. congolense IL 285 was examined in 24 Boran steers. The cattle were repeatedly challenged at monthly intervals between 2 and 7 months following treatment, either by 5 infected ...

Author(s)
Peregrine, A. S.; Ogunyemi, O.; Whitelaw, D. D.; Holmes, P. H.; Moloo, S. K.; Hirumi, H.; Urquhart, G. M.; Murray, M.
Citation
Veterinary Parasitology, 1988, 28, 1-2, pp 53-64
Abstract

Bloodstream trypomastigotes (BSFs) of 2 clones (IL 1392 and IL 3671) of Trypanosoma vivax were cultured without feeder layers in 3 systems. System I: metacyclic-producing cultures of T. vivax IL 1392 were initiated with BSFs derived from infected mice at 27°C in the presence of feeder layers using...

Author(s)
Hirumi, H.; Hirumi, K.; Moloo, S. K.; Shaw, M. K.
Citation
Journal of Protozoology Research, 1991, 1, 15, pp 1-12
Abstract

Twenty-four Boran cattle were injected with isometamidium chloride (1 mg/kg body weight) to investigate the duration of drug-induced prophylaxis against infection by metacyclic forms of T. congolense and to determine if specific antibody responses to the organism were mounted by animals under...

Author(s)
Whitelaw, D. D.; Bell, I. R.; Holmes, P. H.; Moloo, S. K.; Hirumi, H.; Urquhart, G. M.; Murray, M.
Citation
Veterinary Record, 1986, 118, 26, pp 722-726
Abstract

Boran, Hereford, and Guernsey cattle (8 in all) given inocula of 2 × 10 to 4 × 105in vitro-propagated T. congolense, which morphologically resembled metacyclic trypanosomes, had skin reactions in 46 of 48 sites. Parasites cultured in vitro at 28°C and purified through columns of diethylaminoethyl...

Author(s)
Akol, G. W. O.; Murray, M.; Hirumi, H.; Hirumi, K.; Moloo, S. K.
Citation
Acta Tropica, 1986, 43, 3, pp 207-214
Abstract

The residual chemoprophylactic action of Samorin (isometamidium chloride), injected into 18-month-old Boran cattle at 1 mg/kg body weight, was tested by exposing groups of 4 animals at monthly intervals for 5 months to 5 adults of Glossina morsitans centralis infected with Trypanosoma congolense IL ...

Author(s)
Holmes, P. H.; Whitelaw, D. D.; Bell, I.; Moloo, S. K.; Hirumi, H.; Murray, M.; Urquhart, G. M.
Publisher
Organization of African Unity/Scientific, Technical and Research Commission, Nairobi, Kenya
Citation
International Scientific Council for Trypanosomiasis Research and Control. Eighteenth Meeting, Harare (Zimbabwe), 1985., 1985, pp 213-218
Abstract

Six groups of 4 Boran steers each were administered isometamidium chloride (Samorin) at either 0.5 or 1.0 mg/kg bwt. The animals in 4 of these groups were then challenged (at monthly intervals from 2-7 months after treatment) by 5 Glossina morsitans centralis infected with either Trypanosoma...

Author(s)
Peregrine, A. S.; Ogunyemi, O.; Bell, I. R.; Holmes, P. H.; Moloo, S. K.; Hirumi, H.; Murray, M.; Urquhart, G. M.; Whitelaw, D. D.
Citation
Kenya Veterinarian, 1986, 10, 2, pp 27

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