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Abstract

The availability of a safe macrofilaricidal drug would help to accelerate onchocerciasis elimination. A trial was conducted in Cameroon to evaluate the effects of a subcutaneous injectable long-acting formulation of ivermectin (LAFI) on the microfilariae (mf) and adult stages of Onchocerca ochengi. ...

Author(s)
Boussinesq, M.; Enyong Peter; Chounna-Ndongmo, P.; Njouendou, A. J.; Pion, S. D.; Rech, A.; Roberge, C.; Gaudriault, G.; Wanji, S.
Publisher
EDP Sciences S.A., Les Ulis, France
Citation
Parasite, 2020, 27, 36,
Abstract

Background: The front line molecules from filarial worms and other nematodes or helminthes are their Excretory-Secretory (ES) products. Their interaction with the host cells, proteins and immune system accounts for the skin and eye pathology or hyposensitivity observed in human onchocerciasis. ES...

Author(s)
Boursou, D.; Ndjonka, D.; Eisenbarth, A.; Manchang, K.; Paguem, A.; Ngwasiri, N. N.; Vildina, J. D.; Abanda, B.; Krumkamp, R.; Hoorn, S. van; Renz, A.; Achukwi, M. D.; Liebau, E.; Brattig, N. W.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Infectious Diseases, 2018, 18, 200, pp (2 May 2018)
AbstractFull Text

A study was conducted to record the prevalence of aortic onchocercerciasis from February, 2015 to March, 2015 in different cattle slaughter houses at Guwahati. From its origin at heart, at least 8-10 cm long piece of aorta was collected randomly irrespective of age, breed and sex of the subjects....

Author(s)
Rabeya Begam; Saidul Islam; Munmi Saikia; Aditi Kalita; Bulbul, K. H.; Joken Bam; Pallabi Pathak
Publisher
Veterinary Practitioner, c/o Dr. A. K. Gahlot, Bikaner, India
Citation
Veterinary Practitioner, 2015, 16, 2, pp 225-227
Abstract

The presence of Onchocerca guturosa in cattle is responsible for lesions similar to those observed in cases suspected of brucellosis, however, Onchocerca sp. is not a trade barrier, although it is also responsible for economic losses due to the removal of the affected parts of the carcasses. ...

Author(s)
Soares Filho, P. M.; Dias, A. S.; Castro, I. S. P.; Souza, P. G. de; Galvão, M. de F.; Xavier, F. G.
Publisher
Springer, New Delhi, India
Citation
Journal of Parasitic Diseases, 2019, 43, 4, pp 730-732
Abstract

Parafilariosis, stephanofilariosis, melanosis, onchocerciasis and setariosis, whose names evoke more tropical disease than parasites of European cattle, are of varying importance in Europe. Some were well-known when cattle were used as draft animals because of the pathognomonic clinical signs,...

Author(s)
Dorchies, P.; Alzieu, J. P.
Publisher
Point Vétérinaire Italie s.r.l., Milano, Italy
Citation
Summa, Animali da Reddito, 2014, 9, 2, pp 55-59
AbstractFull Text

In this study, total of 400 aorta suspected with parasitic aortitis was investigated between the years 2011-2012 in slaughtered cattle in the Southeastern of Turkey. Particularly arcus aorta and its surroundings were investigated. Macroscopically 32 of 400 (8%), both macroscopically and...

Author(s)
Ozyİldİz, Z.; Yİlmaz, R.; Ozsoy, S. Y.; Ozkul, I. A.
Publisher
Kafkas Üniversitesi, Veteriner Fakültesi Dergisi, Kars, Turkey
Citation
Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 2013, 19, 4, pp 589-594
Abstract

Flubendazole (FLBZ) is a broad-spectrum benzimidazole anthelmintic used in pigs, poultry, and humans. It has been proposed as a candidate for development for use in elimination programmes for lymphatic filariasis and onchocerciasis in humans. Moreover, FLBZ has shown promise in cancer chemotherapy, ...

Author(s)
Maté, M. L.; Geary, T.; Mackenzie, C.; Lanusse, C.; Virkel, G.
Publisher
Wiley, Oxford, UK
Citation
Journal of Veterinary Pharmacology and Therapeutics, 2017, 40, 5, pp 493-499
Abstract

Onchocerciasis, a neglected tropical disease prevalent in western and central Africa, is a major health problem and has been targeted for elimination. The causative agent for this disease is the human parasite Onchocerca volvulus. Onchocerca ochengi and Litomosoides sigmodontis, infectious agents...

Author(s)
Wewer, V.; Makepeace, B. L.; Tanya, V. N.; Peisker, H.; Pfarr, K.; Hoerauf, A.; Dörmann, P.
Publisher
Elsevier Ltd, Oxford, UK
Citation
International Journal for Parasitology, 2017, 47, 14, pp 903-912
Abstract

Background: Recent reports of transmission interruption of Onchocerca volvulus, the causing agent of river blindness, in former endemic foci in the Americas, and more recently in West and East Africa, raise the question whether elimination of this debilitating disease is underway after long-term...

Author(s)
Eisenbarth, A.; Achukwi, M. D.; Renz, A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS Neglected Tropical Diseases, 2016, 10, 2, pp e0004392
Abstract

Background: microRNAs (miRNAs), a class of short, non-coding RNA can be found in a highly stable, cell-free form in mammalian body fluids. Specific miRNAs are secreted by parasitic nematodes in exosomes and have been detected in the serum of murine and dog hosts infected with the filarial nematodes ...

Author(s)
Quintana, J. F.; Makepeace, B. L.; Babayan, S. A.; Ivens, A.; Pfarr, K. M.; Blaxter, M.; Debrah, A.; Wanji, S.; Ngangyung, H. F.; Bah, G. S.; Tanya, V. N.; Taylor, D. W.; Hoerauf, A.; Buck, A. H.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2015, 8, 58, pp (27 January 2015)

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