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Abstract

The presence of protective antibodies to Babesia bovis has been demonstrated by the passive transfer of immunity with serum from carriers to highly susceptible splenectomized calves. The effector mechanism was mediated by antibodies which reacted with the parasitized erythrocytes and emerging...

Author(s)
Mahoney, D. F.
Publisher
Cambridge University Press, Cambridge, UK
Citation
The ruminant immune system in health and disease., 1986, pp 539-554
Abstract

Author(s)
Mahoney, D. F.
Publisher
University of Queensland Press, St. Lucia, Queensland, Australia
Citation
Parasite lives. Papers on parasites, their hosts and their associations. To honour J. F. A. Sprent., 1986, pp 136-147
Abstract

The role of antibodies in protection against B. bovis infection in cattle is reviewed and it is shown that they are an important effector mechanism. The use of protective antigens for vaccine production is also discussed and it is concluded that prospects are good provided techniques for obtaining...

Author(s)
Mahoney, D. F.
Publisher
World Association for the Advancement of Veterinary Parasitology, Perth, W., Australia
Citation
Tropical parasitoses and parasitic zoonoses. (10th Meet. of the WAAVP, Perth, W. Australia, Aug. 1983)., 1983, pp 93-104
Abstract

The circumstances under which protective antibody activity can be demonstrated in cattle infected with B. bovis are discussed.

Author(s)
Mahoney, D. F.
Publisher
Department of Veterinary Medicine, Haryana Agricultural University, Hissar 125004, Haryana, India
Citation
Haemoprotozoan diseases of domestic animals. (Proc. seminar (CwVA Asian/Australian regions), Haryana Agric. Univ., Hissar, India, 27 Oct. to 1 Nov. 1980.), 1983, pp 145-146
Abstract

A review is given of attempts to produce protection against babesial infection by means of antigens derived from infected blood. So far it has been difficult to identify or isolate the antigens involved.

Author(s)
Mahoney, D. F.
Publisher
Academic Press, Inc., New York, USA & London, UK
Citation
Babesiosis. (Internat. Conf. on malaria and babesiosis, Mexico City, 30 Apr. -- 4 May 1979)., 1981, pp 475-483
Abstract

Splenectomized calves and intact cattle were immunized with virulent B. bovis exposed to various levels of irradiation, or with dead lyophilized material. The greatest degree of protection against virulent heterologous challenge was obtained with parasites exposed to 35 krad: this dose reduced the...

Author(s)
Wright, I. G.; Mahoney, D. F.
Publisher
Australian Veterinary Association., Artarmon, NSW, Australia
Citation
Ticks and tick-borne diseases. (Proc. Symp., 56th Ann. Conf., Australian Vet. Ass., Townsville, 14-18 May 1979.), 1980, pp 11-14
Abstract

Further pathophysiological studies of the hypotensive shock syndrome associated with acute B. bovis infection in cattle demonstrated changes in the plasma concentrations of conglutinin, complement C3, fibronectin and immunoconglutinin. Decreases in the first three components are presumably due to...

Author(s)
Goodger, B. V.; Wright, I. G.; Mahoney, D. F.
Publisher
University of Adelaide, Adelaide, Australia
Citation
Australian Journal of Experimental Biology and Medical Science, 1981, 59, 5, pp 531-538
Abstract

Soluble antigen which protected susceptible cattle against challenge with B. bovis was extracted from B. bovis-infected erythrocytes by sonic disintegration and ultracentrifugation. The material was then fractionated by the precipitation of fibrinogen-like proteins. The precipitate contained the...

Author(s)
Mahoney, D. F.; Wright, I. G.; Goodger, B. V.
Citation
Veterinary Immunology and Immunopathology, 1981, 2, 2, pp 145-156
Abstract

The haemolytic activity of serum complement was measured in cattle during B. bovis infection. It fell significantly on the 5th day after infection and was not detectable by the 10th day. After clinical recovery between 15 and 20 days after infection it was again detected in serum and gradually...

Author(s)
Mahoney, D. F.; Wright, I. G.; Goodger, B. V.
Citation
Zeitschrift fur Parasitenkunde, 1980, 62, 1, pp 39-45
Abstract

The plasma of 4 cattle recovering from severe B. bovis infection contained cold precipitable protein which consisted of immune complexes formed in antibody excess. The major immunoglobulin in the complexes was IgM although IgG1 and IgG2 were also present at lower concentrations. In addition,...

Author(s)
Goodger, B. V.; Wright, I. G,; Mahoney, D. F.
Publisher
University of Adelaide, Adelaide, Australia
Citation
Australian Journal of Experimental Biology and Medical Science, 1981, 59, 5, pp 521-529

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