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Abstract

Theileria parva is a tick-transmitted protozoan parasite that causes a disease called East Coast fever (ECF) in cattle. This important tick borne-disease (TBD) causes significant economic losses in cattle in many sub-Saharan countries, including Tanzania. Cattle immunization using Muguga cocktail...

Author(s)
Kerario, I. I.; Chenyambuga, S. W.; Mwega, E. D.; Rukambile, E.; Simulundu, E.; Simuunza, M. C.
Publisher
Elsevier GmbH, München, Germany
Citation
Ticks and Tick-borne Diseases, 2019, 10, 5, pp 1003-1017
Abstract

Tropical theileriosis is a tick-borne haemoparasitic disease of cattle caused by the protozoan parasite Theileria annulata. Globally, the economic impact of the disease is immense and enhanced control measures would improve livestock production in endemic regions. Immunisation with a live...

Author(s)
Bİlgİc, H. B.; Aksulu, A.; Bakırcı, S.; Unlu, A. H.; Kose, O.; Hacılarlıoglu, S.; Weir, W.; Karagenc, T.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2019, 265, pp 63-73
Abstract

Objectives: The objective of this study was to assess whether cytotoxic T cells (CTL) generated by the live vaccine, known as "ITM Muguga cocktail", which is used for the cattle disease East Cost fever (ECF) in Sub-Saharan Africa, showed a broad reactivity against many different strains of the...

Author(s)
Steinaa, L.; Svitek, N.; Awino, E.; Saya, R.; Toye, P.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Research Notes, 2018, 11, 44, pp (17 January 2018)
Abstract

Background: The tick-borne protozoan parasite Theileria parva causes a usually fatal cattle disease known as East Coast fever in sub-Saharan Africa, with devastating consequences for poor small-holder farmers. Immunity to T. parva, believed to be mediated by a cytotoxic T lymphocyte (CTL) response, ...

Author(s)
Steinaa, L.; Svitek, N.; Awino, E.; Njoroge, T.; Saya, R.; Morrison, I.; Toye, P.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2018, 14, 145, pp (2 May 2018)
Abstract

In Tanzania, control of East Coast fever (ECF) has predominantly relied on tick control using acaricides and chemotherapy, little on ECF vaccination, and very little on dissemination regarding animal immunization. In this paper, the prevalence, control measure, and tolerance of Tanzania Shorthorn...

Author(s)
Laisser, E. L. K.; Chenyambuga, S. W.; Karimuribo, E. D.; Msalya, G.; Kipanyula, M. J.; Mwilawa, A. J.; Mdegela, R. H.; Kusiluka, L. J. M.
Publisher
Springer, Amsterdam, Netherlands
Citation
Tropical Animal Health and Production, 2017, 49, 4, pp 813-822
Abstract

East Coast fever (ECF), caused by Theileria parva infection, is a frequently fatal disease of cattle in eastern, central and southern Africa, and an emerging disease in South Sudan. Immunization using the infection and treatment method (ITM) is increasingly being used for control in countries...

Author(s)
Salih, D. A.; Pelle, R.; Mwacharo, J. M.; Njahira, M. N.; Marcellino, W. L.; Kiara, H.; Malak, A. K.; El-Hussein, A. R. M.; Bishop, R.; Skilton, R. A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2017, 12, 2, pp e0171426
Abstract

Theileria annulata merozoite surface protein (Tams1) and native soluble piroplasm antigen of an Indian isolate of T. annulata were used to optimize an enzyme linked immunosorbent assay (ELISA) to detect anti-Theileria antibodies in cross-bred cattle experimentally infected with sporozoites or...

Author(s)
Rajendran, C.; Ray, D. D.
Publisher
Springer, New Delhi, India
Citation
Journal of Parasitic Diseases, 2014, 38, 1, pp 41-45
Abstract

This study was conducted to assess the incremental effect of natural tick challenge on the infection and treatment method-induced immunity against T. parva under agro-pastoral systems in Simanjiro district, Northern Tanzania. T. parva specific antibody percent positivity and prevalence of T. parva...

Author(s)
Kazungu, Y. E. M.; Mwega, E.; Neselle, M. O.; Sallu, R.; Kimera, S. I.; Gwakisa, P.
Publisher
Elsevier GmbH, München, Germany
Citation
Ticks and Tick-borne Diseases, 2015, 6, 5, pp 587-591
AbstractFull Text

Bovine theileriosis is a tick-borne disease caused by obligate intracellular parasites related to the genus Theileria. Cellular immune responses protect cattle against pathogens through the activation of immune cells. Nowadays, live, attenuated vaccine of Theileria annulata (T. annulata) is being...

Author(s)
Habibi, G.
Publisher
Razi Vaccine and Serum Research Institute, Teheran, Iran
Citation
Archives of Razi Institute, 2016, 71, 2, pp 71-79
Abstract

Background: In this study, the pilot production of aerobic bioreactor tropical theileriosis vaccine was optimized with the aim of immunological assays for further mass production. Methods: We have shown earlier the delayed type hypersensitivity (DTH) assay could be used for evaluating the immunity...

Author(s)
Habibi, G.; Esmaeil-Nia, K.; Izadi, H.; Amarloie, O. A.; Afshari, A.; Bordbar, N.
Publisher
Tehran University of Medical Sciences, Tehran, Iran
Citation
Iranian Journal of Parasitology, 2014, 9, 3, pp 382-393

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