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Abstract

Immunization of cattle with in vitro propagated Theileria annulata-infected cell lines induces a protective immune response in the draining lymph node (DLN), which is the site of immune failure in sporozoite infection. The activation status of DLN cells was examined to determine how the response...

Author(s)
Goel, P.; Preston, P. M.; Spooner, R. L.
Publisher
Society for Immunology & Immunopathology, Pantnagar, India
Citation
Journal of Immunology & Immunopathology, 2006, 8, 2, pp article 2
Abstract

Current methods for control of tropical theileriosis in cattle suffer from several disadvantages that could be circumvented by development of an effective sub-unit vaccine. Previous work has utilised two major surface antigens (SPAG-1 and Tams1) and conventional adjuvants to provide partial...

Author(s)
Gharbi, M.; Darghouth, M. A.; Weir, W.; Katzer, F.; Boulter, N.; Adamson, R.; Gilbert, S. C.; Jongejan, F.; Westbroek, I.; Hall, R.; Tait, A.; Shiels, B.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2011, 29, 38, pp 6620-6628
Abstract

The pathogenesis of tropical theileriosis is still unclear. However, it is known that the draining lymph nodes (DLN) are the site for aberrant T cell activation in the diseased animals, whereas it is the site for initiation of immune response in case of vaccinated animals. The DLN responded to the ...

Author(s)
Goel, P.; Campbell, J. D. M.; Nichani, A.; Glass, E. J.; Preston, P. M.; Spooner, R. L.
Publisher
Society for Immunology & Immunopathology, Pantnagar, India
Citation
Journal of Immunology & Immunopathology, 2006, 8, 1, pp article 3
Abstract

The sporozoite surface antigen, SPAG-1 and the attenuated schizont infected Tunisian line CL1 of Theileria annulata have been shown, in previous studies, to induce variable levels of protection against homologous and heterologous sporozoite challenge, respectively. We report here the result of a...

Author(s)
Darghouth, M. A.; Boulter, N. R.; Gharbi, M.; Sassi, L.; Tait, A.; Hall, R.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2006, 142, 1/2, pp 54-62
Abstract

The objective of this study was to investigate the duration of immunity generated by a live vaccine against Theileria annulata infection. Three groups of animals were used. The 1st group was immunized and then challenged 13 months after vaccination. The 2nd group was immunized twice at 16-month...

Author(s)
Ouhelli, H.; Kachani, M.; El-Haj, N.; Raiss, S.
Publisher
École Nationale Vétérinaire de Toulouse, Toulouse, France
Citation
Revue de Médecine Vétérinaire, 2004, 155, 10, pp 472-475
Abstract

A study using a structured questionnaire was conducted to assess the perception of cattle farmers of the efficacy of East Coast fever (ECF) immunization in southern Zambia. One hundred and seventy-nine farmers from five districts in southern Zambia were interviewed. The majority of farmers (85%)...

Author(s)
Fandamu, P.; Thys, E.; Duchateau, L.; Berkvens, D.
Publisher
Springer Science + Business Media, Dordrecht, Netherlands
Citation
Tropical Animal Health and Production, 2006, 38, 1, pp 9-16
Abstract

To evaluate the role of colostral antibodies in the protection of newborn calves against tropical theileriosis, ten pregnant cows were immunized against Theileria annulata. Immunization was done with repeated injections of sporozoites at doses of 0.4, 0.4, 0.4 and 0.8 tick-equivalents. In parallel, ...

Author(s)
El-Haj, N.; Kachani, M.; El-Hasnaoui, M.; Williamson, S.; Ahami, A. T.; Ouhelli, H.
Publisher
École Nationale Vétérinaire de Toulouse, Toulouse, France
Citation
Revue de Médecine Vétérinaire, 2003, 154, 2, pp 97-104
Abstract

Friesian calves were immunized with a recombinant form of the Theileria annulata major sporozoite surface antigen SPAG-1 or the related T. parva antigen p67, which have previously been shown to induce a degree of homologous protection (they also share sequence homology and are serologically...

Author(s)
Hall, R.; Boulter, N. R.; Brown, C. G. D.; Wilkie, G.; Kirvar, E.; Nene, V.; Musoke, A. J.; Glass, E. J.; Morzaria, S. P.
Citation
Parasite Immunology, 2000, 22, 5, pp 223-230
Abstract

Haematological and biochemical changes were studied in 10 Friesian calves after immunization with attenuated T. annulata vaccine and after challenge with virulent strain. 21 naturally infected animals were controls. No significant changes were observed in vaccinated after challenge. However, in...

Author(s)
Farah, A. W.; Soliman, F. A.; El-Din, H. Y. G.; El-Abdin, A. M. Z.
Citation
Veterinary Medical Journal Giza, 1999, 47, 2, pp 255-266
Abstract

The p67 sporozoite antigen of T. parva was fused to the C-terminal secretion signal of Escherichia coli haemolysin and expressed in secreted form by attenuated S. dublin aroA strain SL5631. The recombinant p67 antigen was detected in the supernatant of transformed bacterial cultures. Immunization...

Author(s)
Gentschev, I.; Glaser, I.; Goebel, W.; McKeever, D. J.; Musoke, A.; Heussler, V. T.
Citation
Infection and Immunity, 1998, 66, 5, pp 2060-2064

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