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Abstract

Control of helminth infections is a major task in livestock production to prevent health constraints and economic losses. However, resistance to established anthelmintic substances already impedes effective anthelmintic treatment in many regions worldwide. Thus, there is an obvious need for...

Author(s)
Demeler, J.; Krüger, N.; Krücken, J.; Heyden, V. C. von der; Ramünke, S.; Küttler, U.; Miltsch, S.; López Cepeda, M.; Knox, M.; Vercruysse, J.; Geldhof, P.; Harder, A.; Samson-Himmelstjerna, G. von
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2013, 8, 8, pp e70212
Abstract

Recent reports of suspected ivermectin (IVM) resistance in Ostertagia ostertagi have highlighted the need for research into the mechanisms of IVM resistance. However, there are no reports of resistant field isolates of O. ostertagi, which have been characterized for molecular research. Therefore,...

Author(s)
Zeveren, A. M. van; Casaert, S.; Alvinerie, M.; Geldhof, P.; Claerebout, E.; Vercruysse, J.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2007, 150, 1/2, pp 104-110
Abstract

Previous vaccination trials with calves have shown that intramuscular immunization with natively purified activation-associated secreted proteins (ASPs) of Ostertagia ostertagi induces protection against a homologous challenge infection with a 74% reduction in cumulative faecal egg counts and a...

Author(s)
Meyvis, Y.; Callewaert, N.; Gevaert, K.; Timmerman, E.; Durme, J. van; Schymkowitz, J.; Rousseau, F.; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
Elsevier, Oxford, UK
Citation
Molecular and Biochemical Parasitology, 2008, 161, 1, pp 67-71
Abstract

The cysteine-rich secretory/antigen 5/pathogenesis-related 1 (CAP) protein superfamily is composed of a functionally diverse group of members that are found in both eukaryotes and prokaryotes. The excretome/secretome of numerous helminths (parasitic nematodes) contains abundant amounts of CAP...

Author(s)
Borloo, J.; Geldhof, P.; Peelaers, I.; Meulder, F. van; Ameloot, P.; Callewaert, N.; Vercruysse, J.; Claerebout, E.; Strelkov, S. V.; Weeks, S. D.
Publisher
Wiley-Blackwell, Copenhagen, Denmark
Citation
Acta Crystallographica Section D, Biological Crystallography, 2013, 69, 4, pp 493-503
Abstract

Infections in cattle with the gastric nematode Ostertagia ostertagi are associated with decreased acid secretion and profound physio-morphological changes of the gastric mucosa. The purpose of the current study was to investigate the mechanisms triggering these pathophysiological changes. O....

Author(s)
Mihi, B.; Meulder, F. van; Rinaldi, M.; Coppernolle, S. van; Chiers, K.; Broeck, W. van den; Goddeeris, B.; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
BioMed Central Ltd, London, UK
Citation
Veterinary Research, 2013, 44, 121, pp (11 December 2013)
Abstract

Ostertagia ostertagi is considered one of the most economically important bovine parasites. As an alternative to anthelmintic treatment, an experimental host-protective vaccine was previously developed on the basis of ASP proteins derived from adult worms. Intramuscular injection of this vaccine,...

Author(s)
Meulder, F. van; Coppernolle, S. van; Borloo, J.; Rinaldi, M.; Li, R. W.; Chiers, K.; Broeck, W. van den; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
American Society for Microbiology (ASM), Washington, USA
Citation
Infection and Immunity, 2013, 81, 5, pp 1798-1809
Abstract

The impact of gastrointestinal (GI) nematode infections in dairy farming has traditionally been assessed using partial productivity indicators. But such approaches ignore the impact of infection on the performance of the whole farm. In this study, efficiency analysis was used to study the...

Author(s)
Voort, M. van der; Meensel, J. van; Lauwers, L.; Vercruysse, J.; Huylenbroeck, G. van; Charlier, J.
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Journal of Dairy Science, 2014, 97, 6, pp 3498-3508
Abstract

The main objective of the present study was to evaluate the accuracy of the faecal egg count reduction test (FECRT) to assess the resistance status of ivermectin (IVM)-resistant isolates of the cattle nematodes Ostertagia ostertagi and Cooperia oncophora, using the controlled efficacy test (worm...

Author(s)
Graef, J. de; Sarre, C.; Mills, B. J.; Mahabir, S.; Casaert, S.; Wilde, N. de; Weyenberg, M. van; Geldhof, P.; Marchiondo, A.; Vercruysse, J.; Meeus, P.; Claerebout, E.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Parasitology, 2012, 189, 2/4, pp 378-382
AbstractFull Text

Author(s)
Vercruysse, J.; Charlier, J.; Dorny, P.; Claerebout, E.
Publisher
World Association for Buiatrics, Paris, France
Citation
24th World Buiatrics Congress, Nice, France, 15-19 October, 2006, 2006, pp 354-360
Abstract

This paper compares 2 methods, the coefficient of variation and the geNorm software programme, for the evaluation of 5 potential reference genes in the cattle parasite Ostertagia ostertagi to be used for quantitative real-time polymerase chain reaction (PCR) analysis. Both methods identified Tubb...

Author(s)
Zeveren, A. M. van; Visser, A.; Hoorens, P. R.; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
Elsevier, Oxford, UK
Citation
Molecular and Biochemical Parasitology, 2007, 153, 2, pp 224-227

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