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Abstract

Activation associated secreted proteins (ASP) are members of a nematode-specific protein family belonging to the SCP/Tpx-1/Ag5/PR-1/Sc7 family. Three different types of molecules have been identified in this family: two-domain ASPs and single-domain ASPs showing homology to either the C-terminal or ...

Author(s)
Visser, A.; Zeveren, A. M. van; Meyvis, Y.; Peelaers, I.; Broeck, W. van den; Gevaert, K.; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
Elsevier, Oxford, UK
Citation
International Journal for Parasitology, 2008, 38, 3/4, pp 455-465
Abstract

This paper compares 2 methods, the coefficient of variation and the geNorm software programme, for the evaluation of 5 potential reference genes in the cattle parasite Ostertagia ostertagi to be used for quantitative real-time polymerase chain reaction (PCR) analysis. Both methods identified Tubb...

Author(s)
Zeveren, A. M. van; Visser, A.; Hoorens, P. R.; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
Elsevier, Oxford, UK
Citation
Molecular and Biochemical Parasitology, 2007, 153, 2, pp 224-227
Abstract

The transthyretin-like (ttl) gene family is one of the largest conserved nematode-specific gene families, coding for a group of proteins with significant sequence similarity to transthyretins (TTR) and transthyretin-related proteins (TRP). In the present study, we investigated the ttl family in ...

Author(s)
Saverwyns, H.; Visser, A.; Durme, J. van; Power, D.; Morgado, I.; Kennedy, M. W.; Knox, D. P.; Schymkowitz, J.; Rousseau, F.; Gevaert, K.; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
Elsevier, Oxford, UK
Citation
International Journal for Parasitology, 2008, 38, 13, pp 1545-1556
Abstract

RNA interference (RNAi) on parasitic nematodes has been described as successful and useful for the identification of novel drug and vaccine candidates. In this study we have evaluated this technology on the cattle parasite Ostertagia ostertagi. Eight different genes were targeted in L1 and L3 O....

Author(s)
Visser, A.; Geldhof, P.; Maere, V. de; Knox, D. P.; Vercruysse, J.; Claerebout, E.
Publisher
Cambridge University Press, Cambridge, UK
Citation
Parasitology, 2006, 133, 6, pp 777-783
Abstract

The translationally controlled tumour protein (TCTP) is a conserved protein which has been described for a wide range of eukaryotic organisms including protozoa, yeasts, plants, nematodes and mammals. Several parasitic organisms have been shown to actively secrete TCTP during host infection as part ...

Author(s)
Meyvis, Y.; Houthoofd, W.; Visser, A.; Borgonie, G.; Gevaert, K.; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
Elsevier, Oxford, UK
Citation
International Journal for Parasitology, 2009, 39, 11, pp 1205-1213

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