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Abstract

Currently, foot-and-mouth disease (FMD) vaccine purity is tested in cattle to detect antibodies against the non-structural protein (NSP) after repeated immunization with the final vaccine product. In case of vaccine failure, the manufacturing company would suffer significant economic loss. To...

Author(s)
Kim HyeJin; Kim AhYoung; Kim JaeSeok; Lee JungMin; Lee HyeYoung; Cheong KwangMyun; Kim ByoungHan; Park ChoiKyu; Ko YoungJoon
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2019, 37, 29, pp 3825-3831
Abstract

To prepare foot-and-mouth disease (FMD) recombinant vaccines in response to newly emerging FMD virus (FMDV) field strains, we evaluated Modified Vaccinia virus Ankara-Bavarian Nordic (MVA-BN®) as an FMD vaccine vector platform. The MVA-BN vector has the capacity to carry and express numerous...

Author(s)
Steigerwald, R.; Brake, D. A.; Barrera, J.; Schutta, C. J.; Kalla, M.; Wennier, S. T.; Volkmann, A.; Hurtle, W.; Clark, B. A.; Zurita, M.; Pisano, M.; Kamicker, B. J.; Puckette, M. C.; Rasmussen, M. V.; Neilan, J. G.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2020, 38, 4, pp 769-778
Abstract

The role of foot-and-mouth disease virus (FMDV) persistently infected ruminants in initiating new outbreaks remains controversial, and the perceived threat posed by such animals hinders international trade in FMD-endemic countries. In this study we report longitudinal analyses of genetic and...

Author(s)
Biswal, J. K.; Rajeev Ranjan; Saravanan Subramaniam; Mohapatra, J. K.; Sanjay Patidar; Sharma, M. K.; Bertram, M. R.; Brito, B.; Rodriguez, L. L.; Bramhadev Pattnaik; Arzt, J.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2019, 14, 6, pp e0214832
Abstract

Foot-and-mouth-disease (FMD) is a highly contagious transboundary animal disease that has negative consequences on regional and international trade. Vaccination is an important approach for FMD control and an essential consideration is the degree of cross-protection conferred by the vaccine against ...

Author(s)
Sirdar, M. M.; Fosgate, G. T.; Blignaut, B.; Gummow, B.; Shileyi, B.; Lazarus, D. D.; Mutowembwa, P.; Merwe, D. van der; Heath, L.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2019, 37, 35, pp 5025-5034
Abstract

Foot-and-mouth disease virus (FMDV) is the cause of an economically devastating disease in major cloven-hoofed livestock. Although type C foot-and-mouth disease (FMD) has not occurred anywhere worldwide since 2004, the antigen bank should be preserved in preparation for an unexpected outbreak. We...

Author(s)
You SuHwa; Jo HyeEun; Choi JooHyung; Ko MiKyeong; Shin SungHo; Lee MinJa; Kim SuMi; Kim ByoungHan; Park JongHyeon
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2019, 234, pp 44-50
Abstract

Here, we report the results of a cross-sectional study designed to monitor the circulation and genetic diversity of foot and mouth disease virus (FMDV) in Uganda between 2014 and 2017. In this study, 13,614 sera and 2,068 oral-pharyngeal fluid samples were collected from cattle and analysed to...

Author(s)
Mwiine, F. N.; Velazquez-Salinas, L.; Ahmed, Z.; Ochwo, S.; Munsey, A.; Kenney, M.; Lutwama, J. J.; Maree, F. F.; Lobel, L.; Perez, A. M.; Rodriguez, L. L.; Vanderwaal, K.; Rieder, E.
Publisher
Wiley, Berlin, Germany
Citation
Transboundary and Emerging Diseases, 2019, 66, 5, pp 2011-2024
Abstract

Foot-and-mouth disease virus (FMDV) is a highly contagious virus that causes one of the most devastating diseases in cloven-hoofed animals. Disease symptoms develop within 2 to 3 days of exposure and include fever and vesicular lesions on the tongue and hooves. Dendritic cells (DC) play an...

Author(s)
Sei, J. J.; Waters, R. A.; Kenney, M.; Barlow, J. W.; Golde, W. T.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2016, 11, 3, pp e0152192
Abstract

Foot-and-mouth disease virus (FMDV) causes a highly contagious vesicular disease in livestock, with serious consequences for international trade. The virus persists in the nasopharynx of cattle and this slows down the process to obtain an FMDV-free status after an outbreak. To study biological...

Author(s)
Hägglund, S.; Laloy, E.; Näslund, K.; Pfaff, F.; Eschbaumer, M.; Romey, A.; Relmy, A.; Rikberg, A.; Svensson, A.; Huet, H.; Gorna, K.; Zühlke, D.; Riedel, K.; Beer, M.; Zientara, S.; Bakkali-Kassimi, L.; Blaise-Boisseau, S.; Valarcher, J. F.
Publisher
Wiley, Berlin, Germany
Citation
Transboundary and Emerging Diseases, 2020, 67, 1, pp 133-148
Abstract

Foot-and-mouth disease virus (FMDV) is a highly variable RNA virus existing as seven different serotypes. The antigenic variability between and within serotypes can limit the cross-reactivity and therefore the in vivo cross-protection of vaccines. Selection of appropriate vaccine strains is crucial ...

Author(s)
Willems, T.; Vleeschauwer, A. de; Perez-Filgueira, M.; Li YanMin; Ludi, A.; Lefebvre, D.; Wilsden, G.; Statham, B.; Haas, B.; Mattion, N.; Robiolo, B.; Perez, C. B.; Maradei, E.; Smitsaart, E.; Torre, J. la; Clercq, K. de
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Journal of Virological Methods, 2020, 276, pp 113786
Abstract

Background: Ethiopian livestock production and productivity is still very low due to widespread of diseases. Among the diseases, foot-and-mouth disease (FMD) is an extremely contagious and acute viral disease that causes significant economic problems in the country. A cross sectional study design...

Author(s)
Mishamo Sulayeman; Fufa Dawo; Bedaso Mammo; Daniel Gizaw; Dereje Shegu
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2018, 14, 110, pp (27 March 2018)

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