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Abstract

Neonatal calves possess a very immature and naïve immune system and are reliant on the intake of maternal colostrum for passive transfer of immunoglobulins. Variation in colostrum management of beef and dairy calves is thought to affect early immune development. Therefore, the objective of this...

Author(s)
Surlis, C.; Earley, B.; McGee, M.; Keogh, K.; Cormican, P.; Blackshields, G.; Tiernan, K.; Dunn, A.; Morrison, S.; Arguello, A.; Waters, S. M.
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2018, 8, 1, pp 15461
Abstract

In the present study, we standardized processes of cloning and purification of recombinant bovine interleukin-8 (rbIL-8) from bacterial culture and assessed its biological activity in Holstein cattle. Plasmid containing a subclone of bovine IL-8 was expressed using Escherichia coli BL21 and cell...

Author(s)
Bicalho, M. L. S.; Zinicola, M.; Machado, V. S.; Lima, F. S.; Teixeira, A. G. V.; Narbus, C.; Xavier, M. R.; Higgins, H.; Bicalho, R. C.
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Journal of Dairy Science, 2019, 102, 11, pp 10304-10315
Abstract

Cytokines are immune regulators that play an essential role in regulating immune response against various infections. The present study focused on the possible association between the expression level of Interleukin 10 (IL-10) in blood and milk samples of 25 healthy and 25 mastitic cows in Fars...

Author(s)
Varzandian, B.; Ghaderi-Zefrehei, M.; Hosseinzadeh, S.; Sayyadi, M.; Taghadosi, V.; Varzandian, S.
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2017, 28, 4, pp 294-300
Abstract

Paratuberculosis is chronic granulomatous enteritis of ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP). Whole RNA-sequencing (RNA-Seq) is a promising source of novel biomarkers for early MAP infection and disease progression in cattle. Since the blood transcriptome is widely...

Author(s)
Alonso-Hearn, M.; Canive, M.; Blanco-Vazquez, C.; Torremocha, R.; Balseiro, A.; Amado, J.; Varela-Martinez, E.; Ramos, R.; Jugo, B. M.; Casais, R.
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2019, 9, 10, pp 14845
Abstract

This study aimed to evaluate the effect of repeated intravenous lipopolysaccharide (LPS) infusions in nonlactating heifers on (1) the systemic proinflammatory state as measured by biomarkers in blood and plasma, and (2) endometrial gene expression of candidate transcripts on d 15 of gestation. Our...

Author(s)
Fernandes, A. C. C.; Davoodi, S.; Kaur, M.; Veira, D.; Melo, L. E. H.; Cerri, R. L. A.
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Journal of Dairy Science, 2019, 102, 4, pp 3531-3543
Abstract

Background: The objective of this research was to investigate the variation of gene expression in the blood transcriptome profile of Chinese Holstein cows associated to the milk yield traits. Results: We used RNA-seq to generate the bovine transcriptome from the blood of 23 lactating Chinese...

Author(s)
Bai Xue; Zheng ZhuQing; Liu Bin; Ji XiaoYang; Bai YongSheng; Zhang WenGuang
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2016, 17, Suppl. 7, pp 512
Abstract

Viral infections can play direct or indirect roles in the etiology of the bovine mastitis. Mx dynamin-like GTPase 2 (MX2) gene is a main effector of the antiviral innate immune defense mediated by type I interferon (IFN I), which was demonstrated to confer positive antiviral responses to many...

Author(s)
Chen NingBo; Wang FengQiao; Yu NongQi; Gao Yuan; Huang JiePing; Dang RuiHua; Huang YongZhen; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2018, 29, 2, pp 81-89
Abstract

Ketosis is a major metabolic disorder of high-yielding dairy cows during the transition period. Although metabolic adaptations of the adipose tissue are critical for a successful transition, beyond lipolysis, alterations within adipose tissue during ketosis are not well known. The objective of this ...

Author(s)
Xu QiuShi; Li XiaoBing; Ma Li; Loor, J. J.; Coleman, D. N.; Jia HongDou; Liu GuoWen; Xu Chuang; Wang YaZhe; Li XinWei
Publisher
Oxford University Press, Cary, USA
Citation
Journal of Animal Science, 2019, 97, 7, pp 2837-2849
Abstract

Toll-like receptor 4 (TLR4) mediated activation of the nuclear transcription factor κB (NF-κB) signaling pathway by mastitis initiates expression of genes associated with inflammation and the innate immune response. In this study, the profile of mastitis-induced differential gene expression in the...

Author(s)
Wu Jie; Li Lian; Sun Yu; Huang Shuai; Tang Juan; Yu Pan; Wang GenLin
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2015, 10, 2, pp e0118458
Abstract

Transition dairy cows experience a nutrient deficit, particularly in the immediate postpartum period. At the same time, the inflammatory balance is altered and cows exhibit an immune response primed for inflammatory response rather than tolerance. The mechanistic link that might be underlying the...

Author(s)
Mann, S.; Sipka, A.; Yepes, F. A. L.; Nydam, D. V.; Overton, T. R.; Wakshlag, J. J.
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Journal of Dairy Science, 2018, 101, 10, pp 9360-9370

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