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Abstract

Activation associated secreted proteins (ASP) are members of a nematode-specific protein family belonging to the SCP/Tpx-1/Ag5/PR-1/Sc7 family. Three different types of molecules have been identified in this family: two-domain ASPs and single-domain ASPs showing homology to either the C-terminal or ...

Author(s)
Visser, A.; Zeveren, A. M. van; Meyvis, Y.; Peelaers, I.; Broeck, W. van den; Gevaert, K.; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
Elsevier, Oxford, UK
Citation
International Journal for Parasitology, 2008, 38, 3/4, pp 455-465
Abstract

Anthelmintic resistance is emerging in dairy cattle and this can result in a lack of effective control and production losses. Therefore, sustainable control strategies, such as targeted treatments (TT) and targeted selected treatments (TST), should be adopted by the industry. TT and TST approaches...

Author(s)
Velde, F. V.; Claerebout, E.; Cauberghe, V.; Hudders, L.; Loo, H. van; Vercruysse, J.; Charlier, J.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2015, 212, 3/4, pp 308-317
Abstract

Livestock farming is central to global food security and to the sustainability of rural communities throughout Europe. Animal health management has a major impact on farming efficiency. Although animal health research has provided effective prevention strategies for the major endemic diseases of...

Author(s)
Charlier, J.; Velde, F. V.; Voort, M. van der; Meensel, J. van; Lauwers, L.; Cauberghe, V.; Vercruysse, J.; Claerebout, E.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2015, 212, 1/2, pp 62-67
Abstract

Recent reports of suspected ivermectin (IVM) resistance in Ostertagia ostertagi have highlighted the need for research into the mechanisms of IVM resistance. However, there are no reports of resistant field isolates of O. ostertagi, which have been characterized for molecular research. Therefore,...

Author(s)
Zeveren, A. M. van; Casaert, S.; Alvinerie, M.; Geldhof, P.; Claerebout, E.; Vercruysse, J.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2007, 150, 1/2, pp 104-110
Abstract

Previous vaccination trials with calves have shown that intramuscular immunization with natively purified activation-associated secreted proteins (ASPs) of Ostertagia ostertagi induces protection against a homologous challenge infection with a 74% reduction in cumulative faecal egg counts and a...

Author(s)
Meyvis, Y.; Callewaert, N.; Gevaert, K.; Timmerman, E.; Durme, J. van; Schymkowitz, J.; Rousseau, F.; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
Elsevier, Oxford, UK
Citation
Molecular and Biochemical Parasitology, 2008, 161, 1, pp 67-71
AbstractFull Text

Author(s)
Vercruysse, J.; Charlier, J.; Dorny, P.; Claerebout, E.
Publisher
World Association for Buiatrics, Paris, France
Citation
24th World Buiatrics Congress, Nice, France, 15-19 October, 2006, 2006, pp 354-360
Abstract

This paper compares 2 methods, the coefficient of variation and the geNorm software programme, for the evaluation of 5 potential reference genes in the cattle parasite Ostertagia ostertagi to be used for quantitative real-time polymerase chain reaction (PCR) analysis. Both methods identified Tubb...

Author(s)
Zeveren, A. M. van; Visser, A.; Hoorens, P. R.; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
Elsevier, Oxford, UK
Citation
Molecular and Biochemical Parasitology, 2007, 153, 2, pp 224-227
Abstract

In this study, we isolated and analysed a small heat shock protein (HSP) of Ostertagia ostertagi (Oo-HSP18). Oo-hsp18 is encoded by a single-copy gene and the full-length cDNA represents an 18-kDa protein. The expression of Oo-hsp18 is highly stage specific and restricted to the adult stage. The...

Author(s)
Vercauteren, I.; Maere, V. de; Vercruysse, J.; Stevens, M.; Gevaert, K.; Claerebout, E.
Publisher
American Society of Parasitologists, Lawrence, USA
Citation
Journal of Parasitology, 2006, 92, 6, pp 1244-1250
Abstract

The cysteine-rich secretory/antigen 5/pathogenesis-related 1 (CAP) protein superfamily is composed of a functionally diverse group of members that are found in both eukaryotes and prokaryotes. The excretome/secretome of numerous helminths (parasitic nematodes) contains abundant amounts of CAP...

Author(s)
Borloo, J.; Geldhof, P.; Peelaers, I.; Meulder, F. van; Ameloot, P.; Callewaert, N.; Vercruysse, J.; Claerebout, E.; Strelkov, S. V.; Weeks, S. D.
Publisher
Wiley-Blackwell, Copenhagen, Denmark
Citation
Acta Crystallographica Section D, Biological Crystallography, 2013, 69, 4, pp 493-503
Abstract

Infections in cattle with the gastric nematode Ostertagia ostertagi are associated with decreased acid secretion and profound physio-morphological changes of the gastric mucosa. The purpose of the current study was to investigate the mechanisms triggering these pathophysiological changes. O....

Author(s)
Mihi, B.; Meulder, F. van; Rinaldi, M.; Coppernolle, S. van; Chiers, K.; Broeck, W. van den; Goddeeris, B.; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
BioMed Central Ltd, London, UK
Citation
Veterinary Research, 2013, 44, 121, pp (11 December 2013)

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