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Abstract

Genetic polymorphism has great influences on the improvement of cattle traits. The polymorphism of the same gene family will greatly change the growth traits of cattle, such as the pleomorphic adenoma gene (PLAG) family. Many studies have shown that the PLAG family proteins are the transcription...

Author(s)
Zhong JiaLin; Xu JiaWei; Wang Jian; Wen YiFan; Niu Hui; Zheng Li; He Hua; Peng Kun; He Pan; Shi ShuYue; Huang YinQi; Lei ChuZhao; Dang RuiHua; Lan XianYong; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2019, 689, pp 166-171
Abstract

We report genome characterization of three native Chinese cattle breeds discovering ∼34.3 M SNPs and ∼3.8 M InDels using whole genome resequencing. On average, 10.4 M SNPs were shared amongst the three cattle breeds, whereas, 3.0 M, 4.9 M and 5.8 M were specific to LQ, WN and WS breeds,...

Author(s)
Zhang FengWei; Qu KaiXing; Chen NingBo; Hanif, Q.; Jia YuTang; Huang YongZhen; Dang RuiHua; Zhang JiCai; Lan XianYong; Chen Hong; Huang BiZhi; Lei ChuZhao
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2019, 9, 9, pp 596
Abstract

Polymorphisms in the prion protein gene (PRNP) have been linked with the occurrence of transmissible spongiform encephalopathies and the expression of some phenotypic traits in healthy animals including cattle. The aim of this study was to verify the 23-bp insertion/deletion (indel) within promoter ...

Author(s)
Yang Qing; Zhang SiHuan; Liu LiangLiang; Lei ChuZhao; Qi XingLei; Lin FengPeng; Qu WeiDong; Qi XingShan; Liu JiMing; Wang RongMin; Chen Hong; Lan XianYong
Publisher
Taylor & Francis, Abingdon, UK
Citation
Journal of Applied Animal Research, 2018, 46, 1, pp 505-511
Abstract

Author(s)
Zeng LuLan; Huang BiZhi; Li FangYu; Chen NingBo; Ma ZhiJie; Qu KaiXing; Chen Hong; Lei ChuZhao
Publisher
Wiley, Oxford, UK
Citation
Animal Genetics, 2018, 49, 6, pp 655-656
Abstract

Copy number variation is a large genome variation which usually happens in the noncoding-region, and it may occur at the locus associated with the functional gene to further influence the phenotype. Potassium inwardly-rectifying channel, subfamily J 12 (KCNJ12) gene expressed widely in...

Author(s)
Zheng Li; Xu JiaWei; Li JiChao; Wang DaHui; An QingMing; Xu LinNa; Ma YiLei; Wang Jian; Peng ShuJun; Lei ChuZhao; Lan XianYong; Chen Hong; Huo LiJun; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2019, 689, pp 90-96
Abstract

Eukaryotic translation initiation factor 2-alpha kinase 4 (EIF2AK4, also known as GCN2), which pertains to the family of serine-threonine kinase, is involved in oxidative stress and DNA damage repair. A missense single-nucleotide polymorphism (SNP) (NC_037337.1 g.35615224 T > G) in exon 6 of the ...

Author(s)
Wang KaiYue; Cao YanHong; Rong Yu; Ning QingQing; Jia Peng; Huang YongZhen; Lan XianYong; Dang RuiHua; Chen Hong; Lei ChuZhao
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2019, 9, 6, pp 375
Abstract

Chinese indigenous cattle breeds have abundant genetic resources, which are valuable for the molecular breeding of cattle around the world. Thus, identifying important candidate genes and their genetic markers is very important for cattle molecular breeding. A previous study found that a nonsense...

Author(s)
Zhang SiHuan; Peng Kun; Zhang GuoLiang; Cao Yang; Zhang Meng; Chen Hong; Lei ChuZhao; Lan XianYong; Zhao YuMin
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2019, 9, 7, pp 444
Abstract

Identification of polymorphisms associated with economic traits is important for successful marker-assisted selection in cattle breeding. The family of mammalian sirtuin regulates many biological functions, such as life span extension and energy metabolism. SIRT2, a most abundant sirtuin in...

Author(s)
Sun XiaoMei; Li MingXun; Hao Dan; Hua LiuShuai; Lan XianYong; Lei ChuZhao; Hu ShenRong; Qi XingLei; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2015, 42, 3, pp 729-736
Abstract

Myocyte enhancer factor 2C (MEF2C) gene was annotated for its potential phenotypic effects on bovine stature including body dimensions and body weight. The aim of this study was the analysis of MEF2C as a candidate for bovine stature. Four SNPs including two novel SNPs were identified and the...

Author(s)
Cao XiuKai; Zhan ZhaoYang; Huang YongZhen; Lan XianYong; Lei ChuZhao; Qi XingLei; Chen Hong
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Livestock Science, 2016, 185, pp 106-109
Abstract

Copy number variations (CNVs) recently have been recognized as another important genetic variability followed single nucleotide polymorphisms (SNPs). The guanylate binding protein 2 (GBP2) gene plays an important role in cell proliferation. This study was performed to determine the presence of GBP2 ...

Author(s)
Zhang GuiMin; Zheng Li; He Hua; Song ChengChuang; Zhang ZiJing; Cao XiuKai; Lei ChuZhao; Lan XianYong; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2018, 647, pp 101-106

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