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Abstract

The growth and development of muscle is a complex and multistage process, which is regulated by many factors. In particular, genes related to muscle development play a very important role. Studies have shown that there are two kinds of regulatory functions of genes affecting muscle development. One ...

Author(s)
Wen YiFan; He Hua; Song ChengChuang; Peng ShuJun; Lei ChuChao; Chen Hong; Huang YongZhen
Publisher
Guangxi University, Guangxi, China
Citation
Genomics and Applied Biology, 2018, 37, 7, pp 2825-2831
Abstract

The insulin-like growth factor 1 receptor (IGF1R) plays a vital role in immunomodulation and muscle and bone growth. The copy number variation (CNV) is believed to the reason for many complex phenotypic variations. In this paper, we statistically analyzed the copy number and the expression...

Author(s)
Ma YiLei; Wen YiFan; Cao XiuKai; Cheng Jie; Huang YongZhen; Ma Yun; Hu LinYong; Lei ChuZhao; Qi XingLei; Cao Hui; Chen Hong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2019, 62, 1, pp 171-179
Abstract

The LIM-homeobox gene 3 (LHX3) plays an essential role in pituitary gland and nervous system development. Sequence variants (SVs) in coding and non-coding regions of LHX3 gene have an impact on LHX3 transcription and growth traits in cattle. Previously, we have identified 3 single nucleotide...

Author(s)
Huang YongZhen; Jing YongJie; Sun YuJia; Lan XianYong; Zhang ChunLei; Song EnLiang; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2015, 561, 2, pp 219-224
Abstract

LIM homeobox transcription factor 4 (LHX4) is a LIM homeodomain transcription factor involved in pituitary gland and nervous system development. The aim of this study was to examine the association of the LHX4 polymorphisms with growth traits in beef cattle breed. A total of 7 single nucleotide...

Author(s)
Ren Gang; Huang YongZhen; Wei TianBao; Liu JunXia; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Zhang ZhiYing; Qi XingLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 538, 2, pp 354-360
Abstract

Acyl-CoA dehydrogenase, very long chain (ACADVL), encoding ACADVL protein, targets the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway and plays an important role in body metabolism and oxidation of long chain fatty acid...

Author(s)
Zhang SiHuan; Dang YongLong; Zhang QingFeng; Qin QiaoMei; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2015, 559, 2, pp 184-188
Abstract

AT motif binding factor 1 (ATBF1) gene can promote the expression level of the growth hormone 1 (GH1) gene by binding to the enhancers of the POU1F1 and PROP1 genes; thus, it affects the growth and development of livestock. Considering that the ATBF1 gene also has a close relationship with the...

Author(s)
Xu Han; Zhang SiHuan; Zhang XiaoYan; Dang RuiHua; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2017, 60, 3, pp 285-296
Abstract

As an adaptor protein, SH2B1 is a key regulator of leptin sensitivity, energy balance, growth, and body weight. In this study, we identified three SNPs (snp796, snp823 and snp4368) of the SH2B1 gene in 1028 individuals from five Chinese cattle breeds by PCR-RFLP and sequencing, and investigated...

Author(s)
Yang MingJuan; Qu Lian; Liu JunXia; Lan XianYong; Zhang LiangZhi; Wang Jing; Lei ChuZhao; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Livestock Science, 2012, 143, 2/3, pp 283-288
Abstract

Angiopoietin-like protein 6 (ANGPTL6), which plays an important role in angiogenesis and energy metabolism as a circulating orphan peptide secreted by liver, could produce a potential effect on growth and development of animals. The objective of this study was to detect genetic variations of...

Author(s)
Li AiMin; Lan XianYong; Sun XiaoMei; Gao Yuan; Ma Wei; Ma Yun; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2012, 39, 9, pp 9223-9232
Abstract

The study was conducted to analyse Pit-1 gene as a candidate for genetic markers of growth traits in different Chinese cattle. The single-strand conformation polymorphism method was used to detect genetic polymorphism in the Pit-1 gene and intron 5. Results showed that one single nucleotide...

Author(s)
Yang DongYing; Chen Hong; Lan XianYong; Zhang ZhengFeng; Tang LiGang; Zhang LiangZhi; Wang XinZhuang; Wang YiMin; Niu Hui
Publisher
Asian Network for Biotechnology in Animal Production and Health, Haidian, China
Citation
Animal Biotechnology Bulletin, 2006, 10, 1, pp 356-359
Abstract

The PROP1 protein, encoded by the prophet of Pit-1 (PROP1) gene, exhibits both DNA-binding and transcriptional activation abilities. Its expression leads to the ontogenesis of growth hormone (GH), prolactin (PRL), thyroid-stimulating hormone (TSH), and pituitary hormone. The missense mutation H173R ...

Author(s)
Pan ChuanYing; Wu ChongYang; Jia WenChao; Xu Yao; Lei ChuZhao; Hu ShenRong; Lan XianYong; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 531, 2, pp 398-402

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