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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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Abstract

Copy number variation (CNV) related to complex traits, such as disease and quantitative phenotype, is considered an important and wealthy source of genetic and phenotypic diversity. It suggests that the copy number variation of function gene maybe leads to the phenotypic changes. Kupple like factor ...

Author(s)
Xu JiaWei; Zheng Li; Li LiJuan; Yao YuFei; Hua He; Yang ShiZhen; Wen YiFan; Song ChengChuang; Cao XiuKai; Liu KunPeng; Zhang GuiMin; Yang JiaMeng; Hao Dan; Dang RuiHua; Lan XianYong; Lei ChuZhao; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2019, 680, pp 99-104
Abstract

The paired box 7 (Pax7) gene encoding for the transcription factor can regulate the conversion of stem cells into myogenic cells and participate in the development and regeneration of skeletal muscle. The aims of this study were to detect variations of the Pax7 gene by DNA pool sequencing and...

Author(s)
Xu Yao; Zhou Yang; Wang Ning; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2013, 56, 1, pp 9-15
Abstract

Muscle growth is a complex phenomenon regulated by many factors, whereby net growth results from the combined action of synthesis and turnover. Insulin-like growth factor 2 (IGF2) is a fetal growth and differentiation factor that plays an important role in muscle growth and in myoblast...

Author(s)
Huang YongZhen; Zhan ZhaoYang; Sun YuJia; Wang Jing; Li MingXun; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2013, 56, 6, pp 327-334
Abstract

Paired box 3 (PAX3) belongs to the PAX superfamily of transcription factors and plays essential roles in the embryogenesis and postnatal formation of limb musculature through affecting the survival of muscle progenitor cells. By genetic mapping, PAX3 gene is assigned in the interval of quantitative ...

Author(s)
Xu Yao; Cai HanFang; Zhou Yang; Shi Tao; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Jia YuTang; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2014, 41, 7, pp 4295-4303
Abstract

The transcription factor paired box 6 gene (PAX6) plays a key role during the early development of various organs. In this study, three single nucleotide polymorphisms (SNPs) have been identified in the introns 2, 8 and 11 of the bovine PAX6 gene. 8 haplotypes and 13 diplotypes were revealed and...

Author(s)
Huang YongZhen; Jing YongJie; Wei TianBao; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2013, 40, 12, pp 6775-6784
Abstract

The AT motif-binding factor (ATBF1) not only interacts with protein inhibitor of activated signal transducer and activator of transcription 3 (STAT3) (PIAS3) to suppress STAT3 signaling regulating embryo early development and cell differentiation, but is required for early activation of the...

Author(s)
Zhang XiaoYan; Wu XianFeng; Jia WenChao; Pan ChuanYing; Li XiangCheng; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Asian-Australasian Association of Animal Production Societies, Seoul, Korea Republic
Citation
Asian-Australasian Journal of Animal Sciences, 2015, 28, 10, pp 1394-1406
Abstract

The insulin-induced gene 1 (INSIG1) gene encodes a protein that blocks proteolytic activation of sterol regulatory element binding proteins, which are transcription factors that activate genes that regulate cholesterol, fatty acid, and glucose metabolism. However, similar research for the bovine ...

Author(s)
Sun JiaJie; Gao Yuan; Liu Dong; Ma Wei; Xue Jing; Zhang ChunLei; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2012, 55, 6, pp 429-436

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