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Abstract

Copy number variation (CNV) related to complex traits, such as disease and quantitative phenotype, is considered an important and wealthy source of genetic and phenotypic diversity. It suggests that the copy number variation of function gene maybe leads to the phenotypic changes. Kupple like factor ...

Author(s)
Xu JiaWei; Zheng Li; Li LiJuan; Yao YuFei; Hua He; Yang ShiZhen; Wen YiFan; Song ChengChuang; Cao XiuKai; Liu KunPeng; Zhang GuiMin; Yang JiaMeng; Hao Dan; Dang RuiHua; Lan XianYong; Lei ChuZhao; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2019, 680, pp 99-104
Abstract

WNT-β-Catenin-TCF pathway is involved in carcinogenesis and foetal development. As a member of the WNT gene family, Wnt8A encodes secreted signalling proteins and responds to many biological processes. However, similar research on the effects of genetic variations of Wnt8A gene on growth traits is...

Author(s)
Huang YongZhen; Zou Yong; Lin Qing; He Hua; Zheng Li; Zhang ZiJing; Dang YongLong; Lei ChuZhao; Lan XianYong; Qi XingShan; Chen Hong
Publisher
Indian Academy of Sciences, Bangalore, India
Citation
Journal of Genetics, 2017, 96, 4, pp 535-544
Abstract

NPC1 gene is an important gene closely related to the Niemann-Pick type C (NPC). Mutations in the NPC1 gene tend to cause Niemann-Pick type C, a lysosomal storage disorder. Previous studies have shown that NPC1 protein plays an important role in subcellular lipid transport, homeostasis, platelet...

Author(s)
Dang YongLong; Li MingXun; Yang MingJuan; Cao XiuKai; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Lin Qing; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 540, 2, pp 153-160
Abstract

As an adaptor protein, apart from potentiating Janus kinase 2 (JAK2) activation and promoting the insulin signaling pathway, Src homology 2 B 2 (SH2B2) indirectly takes part in the regulation of glucose uptake through the c-Cb1/CAP/TC10 pathway, which can in turn affect growth. In this study, we...

Author(s)
Yang MingJuan; Fu JunHui; Lan XianYong; Sun YuJia; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 528, 2, pp 314-319
Abstract

Patatin-like phospholipase domain-containing protein 3 (PNPLA3), a member of the patatin like phospholipase domain-containing (PNPLA) family, plays an important role in energy balance, fat metabolism regulation, glucose metabolism and fatty liver disease. Tetra-primer amplification refractory...

Author(s)
Wang ZiNian; Cai HanFang; Li MingXun; Cao XiuKai; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2016, 575, 2 Part 1, pp 191-198
Abstract

Genetic variability and genetic relationships were investigated among eight Chinese cattle breeds using 12 microsatellite markers. Three hundred and fifty-two alleles were detected and the average number of alleles per locus ranged from 8.33±1.67 in the Jiaxian breed to 21.33±5.60 in the Qinchuan...

Author(s)
Sun WeiBin; Chen Hong; Lei ChuZhao; Lei XueQin; Zhang YingHan
Publisher
EDP Sciences, Les Ulis, France
Citation
Genetics, Selection, Evolution, 2008, 40, 6, pp 681-692
Abstract

Four microsatellite loci including BM1824, BM2113, CSSM66 and ETH152 were used to analyze the genetic structure and genetic variation in Chinese Holstein cattle of the Shaanxi district. The result showed that Hardy-Weinburg disequilibrium is significantly high over the four loci. Polymorphism...

Author(s)
Zhang RunFeng; Chen Hong; Zhang ZhengFeng; Zhang YongDe; Lan XianYong
Publisher
Asian Network for Biotechnology in Animal Production and Health, Haidian, China
Citation
Animal Biotechnology Bulletin, 2004, 9, 1, pp 56-59

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